{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:53:44Z","timestamp":1791384824567,"version":"4.3.3"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>In humans nevus lipomatosus cutaneous superficialis (NLCS) is a rare, benign dermal hamartoma characterized by aggregates of adipose tissue within the dermis without any connection to the subcutaneous tissue. Although NLCS is a well-recognized entity, it is considered a rare lesion with limited reports in the human literature. To date, no comparable cases have been reported in dogs and cats. Over the course of one and a half years, six cases (five in dogs, one in a cat), resembling NLCS-like lesions, were examined. In this report, we compare these cases to the human condition regarding macroscopic features, histopathology, sex, and age of the affected patients. In all cases, the dermal lesions were composed of aggregates of well-differentiated adipocytes within the dermis. Given the morphological similarity to the lesion in humans, the term \u201cnevus lipomatosus superficialis-like lesion\u201d might be appropriate. However, given the controversial use of the term \u2018nevus\u2019 in veterinary medicine and a potential for confusion with pigmented lesion, we propose the term \u201csuperficial lipomatous hamartoma\u201d for this entity.<\/jats:p>","DOI":"10.3389\/fvets.2026.1891605","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:08:42Z","timestamp":1791382122000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case series: Superficial lipomatous hamartoma in dogs and cats is a previously unreported NLCS-like dermal lesion"],"prefix":"10.3389","volume":"13","author":[{"given":"Laura","family":"K\u00e4stner","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Medicine, Institute of Veterinary-Pathology, Justus Liebig University Giessen","place":["Giessen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Marchewski","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, Institute of Veterinary-Pathology, Justus Liebig University Giessen","place":["Giessen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Henrich","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, Institute of Veterinary-Pathology, Justus Liebig University Giessen","place":["Giessen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,10,7]]},"reference":[{"key":"ref1","first-page":"304","article-title":"Nevus lipomatosus cutaneous superficialis: a rare case report","volume":"39","author":"Patil","year":"2014","journal-title":"Iran J Med Sci"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/BF01826150","article-title":"\u00dcber einen Naevus lipomatodes cutaneus superficialis der linken Glut\u00e4algegend","volume":"130","author":"Hoffmann","year":"1921","journal-title":"Arch Dermatol Syph"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"e41339","DOI":"10.1097\/MD.0000000000041339","article-title":"Nevus lipomatosus superficialis mimicking ectopic breast tissue: a rare case report","volume":"104","author":"Hwang","year":"2025","journal-title":"Medicine"},{"key":"ref4","first-page":"93103c","article-title":"Nevus lipomatosus cutaneous superficialis: a case report with histologic findings","volume":"3","author":"Ranjkesh","year":"2009","journal-title":"J Turk Acad Dermatol"},{"key":"ref5","first-page":"35","volume-title":"Histological Classification of Epithelial and Melanocytic Tumors of the Skin of Domestic Animals","author":"Goldschmidt","year":"1998"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1590\/abd1806-4841.20175217","article-title":"Nevus lipomatosus cutaneous superficialis","volume":"92","author":"Lima","year":"2017","journal-title":"An Bras Dermatol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1111\/j.1365-2133.2006.07622.x","article-title":"Naevus lipomatosus superficialis: a case report with a 2p24 deletion","volume":"156","author":"Cardot-Leccia","year":"2007","journal-title":"Br J Dermatol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1111\/j.1600-0560.1980.tb01198.x","article-title":"Nevus lipomatosus cutaneous superficialis: an electron microscopic study of four cases","volume":"7","author":"Reymond","year":"1980","journal-title":"J Cutan Pathol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s13555-011-0006-y","article-title":"Nevus lipomatosus cutaneous superficialis: report of eight cases","volume":"1","author":"Goucha","year":"2011","journal-title":"Dermatol Ther"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1111\/cup.14552","article-title":"Nevus lipomatosus superficialis: a series of six cases","volume":"51","author":"AbdullGaffar","year":"2024","journal-title":"J Cutan Pathol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1001\/archderm.1984.01650390098021","article-title":"Nevus lipomatosus cutaneus superficialis: a light and electron microscopic study","volume":"120","author":"Dotz","year":"1984","journal-title":"Arch Dermatol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"e102241","DOI":"10.7759\/cureus.102241","article-title":"Clinicopathological spectrum of nevus lipomatosus superficialis: insights from a single-center study","volume":"18","author":"Mawlong","year":"2026","journal-title":"Cureus"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"14","DOI":"10.22271\/veterinary.2025.v10.i7a.2371","article-title":"Cutaneous hamartomas in dogs: epidemiology and pathology","volume":"10","author":"Palekkodan","year":"2025","journal-title":"Int J Vet Sci Anim Husband"},{"key":"ref14","first-page":"e161","article-title":"Nevus lipomatosus superficialis","volume":"50","author":"Yap","year":"2009","journal-title":"Singapore Med J"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjad153","article-title":"Giant pedunculated lipofibroma of the thigh","author":"Suleiman","year":"2023","journal-title":"J Surg Case Rep"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1111\/j.1346-8138.2000.tb02168.x","article-title":"Pedunculated lipofibroma","volume":"27","author":"\u00d6zt\u00fcrkcan","year":"2000","journal-title":"J Dermatol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0190-9622(94)70154-7","article-title":"Pedunculated lipofibroma: a clinicopathologic study of 32 cases supporting a simplified nomenclature","volume":"31","author":"Nogita","year":"1994","journal-title":"J Am Acad Dermatol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1093\/ajcp\/aqab075","article-title":"Revisiting solitary pedunculated lipofibromas","volume":"156","author":"Adotama","year":"2021","journal-title":"Am J Clin Pathol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.mpsur.2021.11.021","article-title":"Surgical anatomy of the skin","volume":"40","author":"Mohamed","year":"2022","journal-title":"Surgery (Oxford)"}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2026.1891605\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:08:49Z","timestamp":1791382129000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2026.1891605\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,7]]},"references-count":19,"alternative-id":["10.3389\/fvets.2026.1891605"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2026.1891605","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,7]]},"article-number":"1891605"}}