{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:54:40Z","timestamp":1790747680443,"version":"4.1.0"},"reference-count":54,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Feedlot nutrition is formulated to maximize growth rate and feed efficiency for high-quality meat production; however, high-grain diets can disrupt rumen function and cause digestive disorders, the inclusion of non-nutritive feed additives helps counter these effects, thereby enhancing growth performance and overall feed efficiency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The present study was carried out to delineate the effect of feeding\n                      <jats:italic>Saccharomyces cerevisiae<\/jats:italic>\n                      strain 1,026 as probiotic and sodium bicarbonate as exogenous buffer on performance of feedlot crossbred lambs. Fifteen crossbred lambs were selected and divided equally into three treatment groups\n                      <jats:italic>viz<\/jats:italic>\n                      ., FT, FT-P and FT-SB. In FT group, animals were fed feedlot diet only; while in FT-P and FT-SB groups,\n                      <jats:italic>Saccharomyces cerevisiae<\/jats:italic>\n                      and sodium bicarbonate were offered as feed additives, respectively. A 74-days feeding trial was conducted, including 10-days metabolism trial at the end.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      No effect (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;gt;\u202f0.05) was observed in dry matter intake (DMI), body weight indices, feed conversion ratio (FCR), digestibility coefficients of nutrients and haemato-biochemical parameters. Rumen pH was significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05) higher in FT-P group than FT group. Dressing percentage showed significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05) higher values in FT-P group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The present experiment validates that feeding of\n                      <jats:italic>Saccharomyces cerevisiae<\/jats:italic>\n                      had more beneficial effect than sodium bicarbonate feeding on the performance of feedlot lambs.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fvets.2026.1964601","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:56:04Z","timestamp":1790744164000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative analysis of feeding probiotic and exogenous buffer on growth performance, nutrient utilization, blood biochemistry, rumen fermentation pattern and carcass characteristics of crossbred lambs reared under feedlot"],"prefix":"10.3389","volume":"13","author":[{"given":"Qazi Shehriyar","family":"Sahib","sequence":"first","affiliation":[{"name":"Division of Animal Nutrition, Faculty of Veterinary Sciences and Animal Husbandry, SKUAST-Kashmir","place":["Srinagar, Jammu and Kashmir, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haidar Ali","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Division of Animal Nutrition, Faculty of Veterinary Sciences and Animal Husbandry, SKUAST-Kashmir","place":["Srinagar, Jammu and Kashmir, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ifla","family":"Aafaq","sequence":"additional","affiliation":[{"name":"Division of Animal Nutrition, Faculty of Veterinary Sciences and Animal Husbandry","place":["Jammu, Jammu and Kashmir, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javid","family":"Farooq","sequence":"additional","affiliation":[{"name":"Division of Animal Nutrition, Faculty of Veterinary Sciences and Animal Husbandry, SKUAST-Kashmir","place":["Srinagar, Jammu and Kashmir, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahir","family":"Nazir","sequence":"additional","affiliation":[{"name":"Division of Livestock Products Technology, Faculty of Veterinary Sciences and Animal Husbandry, SKUAST-Kashmir","place":["Srinagar, Jammu and Kashmir, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubair Ahmad","family":"Akhoon","sequence":"additional","affiliation":[{"name":"Division of Clinical Veterinary Medicine, Ethics and Jurisprudence, Faculty of Veterinary Sciences and Animal Husbandry, SKUAST-Kashmir","place":["Srinagar, Jammu and Kashmir, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2270","DOI":"10.1590\/s1516-35982009001100029","article-title":"Rentabilidade da produ\u00e7\u00e3o de ovinos de corte em pastagem e em confinamento","volume":"38","author":"Barros","year":"2009","journal-title":"Rev Bras Zootec"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1080\/09291016.2019.1603688","article-title":"Immunological and plasma antioxidant response following protection of newborn lambs from cold by umbrella-type housing and lamb-jacket in winter","volume":"52","author":"Sahoo","year":"2021","journal-title":"Biol Rhythm Res"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"352","DOI":"10.33545\/26174693.2024.v8.i3se.765","article-title":"Effect of feeding high concentrate ration on blood-biochemistry and rumen fermentation pattern of sheep","volume":"8","author":"Sahib","year":"2024","journal-title":"Int J Adv Biochem Res"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2769","DOI":"10.1007\/s11250-020-02282-x","article-title":"Precision finishing of south African lambs in feedlots: a review","volume":"52","author":"Van Der Merwe","year":"2020","journal-title":"Trop Anim Health Prod"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.cvfa.2007.04.002","article-title":"Acidosis in feedlot cattle","volume":"23","author":"Nagaraja","year":"2007","journal-title":"Vet Clin North Am Food Anim Pract"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/s0749-0720(15)30814-8","article-title":"Nutritional and dietary interrelationships with diseases of feedlot cattle","volume":"7","author":"Johnson","year":"1991","journal-title":"Vet Clin North Am Food Anim Pract"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"E17","DOI":"10.3168\/jds.2006-478","article-title":"Ruminal acidosis in beef cattle: the current microbiological and nutritional outlook","volume":"90","author":"Nagaraja","year":"2007","journal-title":"J Dairy Sci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.cvfa.2017.06.003","article-title":"Diagnosis and treatment of clinical rumen acidosis","volume":"33","author":"Snyder","year":"2017","journal-title":"Vet Clin North Am Food Anim Pract"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"275","DOI":"10.2527\/1998.761275x","article-title":"Acidosis in cattle: a review","volume":"76","author":"Owens","year":"1998","journal-title":"J Anim Sci"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"85","DOI":"10.22034\/as.2020.11494","article-title":"Comparison of the effect of sodium bicarbonate buffer with Megasphaera elsdenii as a rumen-consuming acid on growth performance, digestibility, rumen and blood parameters of lambs in high concentrate","volume":"30","author":"Khorasani","year":"2020","journal-title":"Anim Sci Res"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.anifeedsci.2011.12.007","article-title":"Is subacute ruminal acidosis a pH related problem? Causes and tools for its control","volume":"172","author":"Calsamiglia","year":"2012","journal-title":"Anim Feed Sci Technol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"8564","DOI":"10.1128\/aem.02443-12","article-title":"Lactate and acrylate metabolism by Megasphaera elsdenii under batch and steady-state conditions","volume":"78","author":"Prabhu","year":"2012","journal-title":"Appl Environ Microbiol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1866","DOI":"10.3168\/jds.2018-15243","article-title":"Symposium review: the importance of the ruminal epithelial barrier for a healthy and productive cow","volume":"102","author":"Aschenbach","year":"2019","journal-title":"J Dairy Sci"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"3222","DOI":"10.3168\/jds.s0022-0302(98)75886-2","article-title":"The importance of pH in the regulation of ruminal acetate to propionate ratio and methane production in vitro","volume":"81","author":"Russell","year":"1998","journal-title":"J Dairy Sci"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"32","DOI":"10.56093\/IJAN.v42i1.5","article-title":"Effect of feeding exogenous buffer (sodium bicarbonate) as feed additive on the performance of feedlot lambs","volume":"42","author":"Sahib","year":"2025","journal-title":"Indian J Anim Nutr"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1590\/rbz4820180129","article-title":"Replacing sodium bicarbonate with half amount of calcareous marine algae in the diet of beef cattle","volume":"48","author":"Rossi","year":"2019","journal-title":"Rev Bras Zootec"},{"key":"ref17","volume-title":"Nutrient Requirements of Animals","year":"2013"},{"key":"ref18","volume-title":"Official Methods of Analysis, Association of Official Analytical Chemistry","year":"2012"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"3583","DOI":"10.3168\/jds.s0022-0302(91)78551-2","article-title":"Methods for dietary Fiber, neutral detergent Fiber, and nonstarch polysaccharides in relation to animal nutrition","volume":"74","author":"Van Soest","year":"1991","journal-title":"J Dairy Sci"},{"key":"ref20","article-title":"The analysis of mineral constituents in biological materials. 1. Estimation of phosphorus, chlorine, calcium, magnesium, sodium and potassium in food-stuffs.","volume-title":"Indian J Vet Sci","author":"Talapatra","year":"1940"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1017\/s0021859600036157","article-title":"Studies on the production of volatile fatty acids from grass by rumen liquor in an artificial rumen: II. The volatile fatty acid production from dried grass","volume":"49","author":"John","year":"1957","journal-title":"J Agric Sci"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"284","DOI":"10.2527\/jas1958.172284x","article-title":"Utilization and\/or synthesis of valeric acid during the digestion of glucose, starch and cellulose by rumen micro-organisms in vitro1","volume":"17","author":"Cline","year":"1958","journal-title":"J Anim Sci"},{"key":"ref23","first-page":"69","article-title":"Influence of yeast culture on productive performance of intensively fattened Pelibuey lambs in Colima, M\u00e9xico","volume":"10","author":"Macedo","year":"2006","journal-title":"Av En Investig Agropecu"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"265","DOI":"10.5455\/ijlr.20171123091936","article-title":"Postprandial changes in rumen microflora and fermentation pattern in sheep fed Paddy straw based complete feed supplemented with probiotics mix","volume":"8","author":"Sheikh","year":"2018","journal-title":"Int J Livest Res"},{"key":"ref25","first-page":"12","article-title":"DFMs improve health, performance of cattle","volume":"77","author":"McDonald","year":"2005","journal-title":"Feedstuffs"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.livsci.2010.06.007","article-title":"Effect of yeast cultures supplementation on live weight change, rumen fermentation, ciliate protozoa population, microbial hydrolytic enzymes status and slaughtering performance of growing lamb","volume":"135","author":"Tripathi","year":"2011","journal-title":"Livest Sci"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"2502","DOI":"10.2527\/jas.2010-3265","article-title":"Tolerance of cattle to increased dietary sulfur and effect of dietary cation-anion balance","volume":"89","author":"Spears","year":"2011","journal-title":"J Anim Sci"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"2664","DOI":"10.2527\/jas.2008-0906","article-title":"Immunobiochemical status of sheep exposed to periods of experimental protein deficit and realimentation","volume":"87","author":"Sahoo","year":"2009","journal-title":"J Anim Sci"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"145","DOI":"10.4141\/cjas95-019","article-title":"Effects of dietary cation\u2013anion concentrations on performance and acid\u2013base balance in growing lambs","volume":"75","author":"Fauchon","year":"1995","journal-title":"Can J Anim Sci"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/s0377-8401(99)00099-1","article-title":"Effect of sodium bicarbonate supplementation and variation in the proportion of barley and sugar beet pulp on growth performance and rumen, blood and carcass characteristics of young entire male lambs","volume":"82","author":"Mandebvu","year":"1999","journal-title":"Anim Feed Sci Technol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"723","DOI":"10.2527\/jas.2008-1031","article-title":"Use of a commercial probiotic supplement in meat goats1","volume":"87","author":"Whitley","year":"2009","journal-title":"J Anim Sci"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s11250-012-0257-3","article-title":"Effect of yeast supplementation on the growth performance of Malpura lambs","volume":"45","author":"Soren","year":"2013","journal-title":"Trop Anim Health Prod"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1093\/jas\/sky011","article-title":"Effects of a live yeast in natural-program finishing feedlot diets on growth performance, digestibility, carcass characteristics, and feeding behavior1","volume":"96","author":"Ovinge","year":"2018","journal-title":"J Anim Sci"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.5713\/ajas.2008.70735","article-title":"Effect of feed additives in growing lambs fed diets containing wet brewers grains","volume":"21","author":"Aguilera-Soto","year":"2008","journal-title":"Asian Australas J Anim Sci"},{"key":"ref35","article-title":"Effects of varying levels of DCAD with two levels of MG and K on acid base status, MG metabolism and productive performance of beetal goats","volume":"24","author":"Farooq","year":"2014","journal-title":"J Anim Plant Sci"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1017\/s1751731115001548","article-title":"Effect of dietary cation\u2013anion difference on ruminal metabolism, total apparent digestibility, blood and renal acid\u2013base regulation in lactating dairy cows","volume":"10","author":"Martins","year":"2016","journal-title":"Animal"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"403","DOI":"10.5958\/2231-6744.2018.00061.0","article-title":"Influence of dietary cation-anion difference based diet on nutrient intake and growth performance of crossbred calves in winter","volume":"35","author":"Suman","year":"2018","journal-title":"Indian J Anim Nutr"},{"key":"ref38","first-page":"597","article-title":"Effect of biological additives on growth indices and physiological responses of weaned Najdi ram lambs","volume":"2","author":"Hussein","year":"2014","journal-title":"J Exp Biol Agric Sci"},{"key":"ref39","first-page":"175","article-title":"Probiotic application in lambs nutrition","volume":"48","author":"Antunovi\u0107","year":"2006","journal-title":"Krmiva Casopis O Hranidbi Zivotinja Proizv Tehnol Krme"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"547","DOI":"10.5713\/ajas.2008.70353","article-title":"Effect of monensin and live yeast supplementation on growth performance, nutrient digestibility, carcass characteristics and ruminal fermentation parameters in lambs fed steam-flaked corn-based diets","volume":"21","author":"Ding","year":"2008","journal-title":"Asian Australas J Anim Sci"},{"key":"ref41","article-title":"Biological Treatments of poor Quality Roughage and its effect on Productive Performance of Ruminants","author":"El-Marakby","year":"2003","journal-title":"Sci Thesis Anim Prod Depart Fac Agric Zagazeg Univ"},{"key":"ref42","volume-title":"Milchwissenschaft","author":"El-Nor","year":"1998"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"2533","DOI":"10.3168\/jds.s0022-0302(98)70146-8","article-title":"Review: effect of protein nutrition on ovarian and uterine physiology in dairy cattle","volume":"81","author":"Butler","year":"1998","journal-title":"J Dairy Sci"},{"key":"ref44","first-page":"26","volume-title":"The Evolution of Yeast Cultures-20 Years of Research","author":"Dawson","year":"2002"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s12917-017-1264-4","article-title":"Comparative assessment of probiotics and monensin in the prophylaxis of acute ruminal lactic acidosis in sheep","volume":"14","author":"Reis","year":"2018","journal-title":"BMC Vet Res"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/0921-4488(88)90042-9","article-title":"Effect of sodium bicarbonate on milk yield and milk composition of goats and on rumen fermentation of kids","volume":"1","author":"Hadjipanayiotou","year":"1988","journal-title":"Small Rumin Res"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1017\/s1751731108001675","article-title":"Increasing sodium bicarbonate level in high-concentrate diets for heifers. I. Effects on intake, water consumption and ruminal fermentation","volume":"2","author":"Gonz\u00e1lez","year":"2008","journal-title":"Animal"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"4196","DOI":"10.3168\/jds.2009-2975","article-title":"Effects of dietary cation-anion difference on ruminal metabolism and blood acid-base regulation in dairy cows receiving 2 contrasting levels of concentrate in diets","volume":"93","author":"Apper-Bossard","year":"2010","journal-title":"J Dairy Sci"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1111\/jpn.12173","article-title":"Use of NaHCO3 and MgO as additives for sheep fed only pasture for a restricted period of time per day: effects on intake, digestion and the rumen environment","volume":"98","author":"P\u00e9rez-Ruchel","year":"2014","journal-title":"J Anim Physiol Anim Nutr"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.smallrumres.2005.09.010","article-title":"Effects of sodium bicarbonate and yeast on nutrient intake, digestibility, and ruminal fermentation of light-weight lambs fed finishing diets","volume":"67","author":"Kawas","year":"2007","journal-title":"Small Rumin Res"},{"key":"ref51","first-page":"137","article-title":"Evaluation of groundnut straw based complete feed blocks alone and in combination with yeast in ration of sheep","volume":"9","author":"Garg","year":"2009","journal-title":"Anim Nutr Feed Technol"},{"key":"ref52","first-page":"40","article-title":"Effect of yeast and fungi culture on in vitro ruminal fermentation","volume":"26","author":"Malik","year":"2009","journal-title":"Indian J Anim Nutr"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/j.meatsci.2012.10.012","article-title":"Effect of concentrate level and slaughter body weight on growth performances, carcass traits and meat quality of Barbarine lambs fed oat hay based diet","volume":"93","author":"Majdoub-Mathlouthi","year":"2013","journal-title":"Meat Sci"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.4314\/sajas.v42i5.4","article-title":"The effects of an active live yeast product on the growth performance of finishing lambs","volume":"42","author":"Pienaar","year":"2012","journal-title":"S Afr J Anim Sci"}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2026.1964601\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:56:07Z","timestamp":1790744167000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2026.1964601\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":54,"alternative-id":["10.3389\/fvets.2026.1964601"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2026.1964601","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]},"article-number":"1964601"}}