{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:46:52Z","timestamp":1773967612344,"version":"3.50.1"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Oncol. Rev."],"abstract":"\n Objective<\/jats:title>\n \n To Compare the effects between thulium laser\n en bloc<\/jats:italic>\n resection of bladder tumor (ERBT) and conventional transurethral resection of bladder tumor (TURBT) on catheter-related bladder discomfort (CRBD) in patients with bladder cancer.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Between January 2022 and December 2024, we retrospectively collected the demographic and clinical data for patients with bladder cancer. A total of 79 patients in the conventional TURBT group and 58 patients in the thulium laser ERBT group completed the study. Both demographic and outcome variables were recorded; and we compared the incidence and severity of CRBD at 1, 6 and 24\u00a0h postoperatively, score of postoperative pain at 1, 6 and 24\u00a0h and patient satisfaction at 24\u00a0h following the surgery.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n There were no significant differences in age, gender proportion, tumor multiplicity, tumor size and location, and duration of surgery between the two groups (\n P &gt;<\/jats:italic>\n 0.05). Pathological examination revealed that the ERBT had a higher rate of detrusor presence than TURBT (\n P<\/jats:italic>\n = 0.04). The incidence and severity of postoperative CRBD were lower in ERBT group than TURBT group at 1 and 6h (\n P<\/jats:italic>\n &lt; 0.001), while there were no statistically significant difference between the two groups (\n P<\/jats:italic>\n = 0.17) at 24\u00a0h. The VAS scores of postoperative pain were significantly lower in ERBT group than in TURBT group at 1 and 6\u00a0h postoperatively (\n P<\/jats:italic>\n = 0.001 and\n P<\/jats:italic>\n = 0.02, respectively). But at 24\u00a0h, there was no statistically significant difference (\n P<\/jats:italic>\n = 0.08). As to postoperative patient satisfaction at 24\u00a0h, the result of ERBT group was significantly lower than TURBT group (\n P<\/jats:italic>\n = 0.02). Additionally, the ERBT group had significantly less intraoperative blood loss and shorter postoperative irrigation duration (\n P<\/jats:italic>\n = 0.001). No significant difference was found in the duration of indwelling catheter between the two groups (\n P<\/jats:italic>\n = 0.07).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The results suggest that compared to conventional TURBT, thulium laser ERBT significantly reduce CRBD incidence and severity, lower postoperative pain, and improve postoperative patient satisfaction. However, as a single-center retrospective study, these findings require further validation by large-scale, prospective, multicenter trials.<\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/or.2025.1653825","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T05:20:05Z","timestamp":1762924805000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of thulium laser en bloc resection of bladder tumor and transurethral resection of bladder tumor on catheter-related bladder discomfort- a single center 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