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Res."],"abstract":"<jats:p>Hairy cell leukaemia (HCL) is a rare B cell malignancy with an indolent course leading to pancytopaenia due to bone marrow infiltration. It has been proposed that HCL patients are at risk of developing a secondary malignancy, with a marked likelihood of the development of other hematologic malignancies including Hodgkin lymphoma and high-grade non-Hodgkin lymphomas. Here, we present the case of two patients who developed diffuse large B cell lymphoma after a long course of hairy cell leukaemia. In the case of the female patient, we report on the occurrence of a third malignant disease, which is very uncommon. With our case descriptions we contribute to the very small number of similar cases reported.<\/jats:p>","DOI":"10.3389\/pore.2022.1610338","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T04:11:23Z","timestamp":1651205483000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Development of Diffuse Large B Cell Lymphoma a Long Time After Hairy Cell Leukemia"],"prefix":"10.3389","volume":"28","author":[{"given":"Zs\u00f3fia 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