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Radiotherapy after breast-conserving surgery (BCS) is indicated in ductal carcinoma <jats:italic>in situ<\/jats:italic> (stage 0), as RT decreases the risk of local recurrence (LR) by 50\u201360%. In early stage (stage I-II) invasive breast cancer RT remains a standard treatment following BCS. However, in elderly (\u226570\u00a0years) patients with stage I, hormone receptor-positive tumour, hormonal therapy without RT can be considered. Hypofractionated whole breast irradiation (WBI) and for selected cases accelerated partial breast irradiation are validated treatment alternatives to conventional WBI administered for 5\u00a0weeks. Following mastectomy, RT significantly decreases the risk of LR and improves overall survival of patients who have 1 to 3 or \u22654 positive axillary lymph nodes. In selected cases of patients with 1 to 2 positive sentinel lymph nodes axillary dissection can be substituted with axillary RT. 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