{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:15:37Z","timestamp":1790784937094,"version":"4.1.0"},"reference-count":35,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["por-journal.com"],"crossmark-restriction":true},"short-container-title":["Pathol. Oncol. Res."],"abstract":"<jats:p>Herein, we detail a multidisciplinary approach and sequential treatment for two infants with congenital granular cell epulis (CGCE). Ultrasonic examinations at 34\u00a0weeks of gestation revealed prominent oral masses in both fetuses. To devise a carefully considered treatment strategy, a comprehensive multidisciplinary consultation including oral and maxillofacial surgeons, pediatricians, obstetricians, and anesthesiologists was convened. Following cesarean sections, the lesions were successfully removed, measuring approximately 30 \u00d7 15\u00a0mm and 30 \u00d7 20\u00a0mm in size, respectively. Immunohistochemical analysis showed that vimentin was positive, S-100 protein was negative, and NSE protein and CD68 protein were negative. These findings underscore the importance of prenatal diagnosis of congenital granular cell epulis for the effective management of these rare benign conditions.<\/jats:p>","DOI":"10.3389\/pore.2024.1611834","type":"journal-article","created":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T04:11:16Z","timestamp":1720584676000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["From prenatal diagnosis to surgical treatment: two case reports of congenital granular cell epulis"],"prefix":"10.3389","volume":"30","author":[{"given":"Yibing","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengmeng","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaohua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuoqing","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,7,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.bjoms.2008.04.007","article-title":"Prenatal and postnatal management of congenital granular cell tumours: a case report","volume":"47","author":"Williams","year":"2009","journal-title":"Br J Oral Maxillofac Surg"},{"key":"B2","doi-asserted-by":"publisher","first-page":"bcr0120125483","DOI":"10.1136\/bcr.01.2012.5483","article-title":"Congenital epulis","volume":"2012","author":"Merglov\u00e1","year":"2012","journal-title":"BMJ Case Rep"},{"key":"B3","first-page":"189","article-title":"Ein von congenital epulis","volume":"12","author":"Neumann","year":"1871","journal-title":"Arch Heilkd"},{"key":"B4","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1159\/000016880","article-title":"Ingested foreign bodies within the appendix: a 100-year review of the literature","volume":"16","author":"Klingler","year":"1998","journal-title":"Dig Dis"},{"key":"B5","doi-asserted-by":"publisher","first-page":"508780","DOI":"10.1155\/2009\/508780","article-title":"Congenital epulis: a case report and estimation of incidence","volume":"2009","author":"Bosanquet","year":"2009","journal-title":"Int J Otolaryngol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/0030-4220(93)90206-j","article-title":"Investigation into the histogenesis of congenital epulis of the newborn","volume":"76","author":"Damm","year":"1993","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"B7","first-page":"739","article-title":"Congenital epulis","volume":"18","author":"Koch","year":"1997","journal-title":"AJNR"},{"key":"B8","doi-asserted-by":"publisher","first-page":"17","DOI":"10.47338\/jns.v4.170","article-title":"Congenital granular cell tumor - a rare entity","volume":"4","author":"Yuwanati","year":"2015","journal-title":"J Neonatal Surg"},{"key":"B9","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1007\/BF00734843","article-title":"Ultrastructure of the congenital epulis","volume":"401","author":"Kameyama","year":"1983","journal-title":"Virchows Arch A Pathol Anat Histopathol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1002\/1097-0142(19840501)53:9<1845::aid-cncr2820530908>3.0.co;2-l","article-title":"Congenital granular cell epulis. 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