{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T20:49:58Z","timestamp":1789591798040,"version":"build-2803163510"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011074","name":"Liver Center, University of California, San Francisco","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011074","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontierspartnerships.org"],"crossmark-restriction":true},"short-container-title":["Transpl Int"],"abstract":"<jats:p>Donation-after-circulatory-death (DCD), donation-after-brain-death (DBD), and living-donation (LD) are the three possible options for liver transplantation (LT), each with unique benefits and complication rates. We aimed to compare DCD-, DBD-, and LD-LT-specific graft survival and biliary complications (BC). We collected data on 138 DCD-, 3,027 DBD- and 318 LD-LTs adult recipients from a single center and analyzed patient\/graft survival. BC (leak and anastomotic\/non-anastomotic stricture (AS\/NAS)) were analyzed in a subset of 414 patients. One-\/five-year graft survival were 88.6%\/70.0% for DCD-LT, 92.6%\/79.9% for DBD-LT, and, 91.7%\/82.9% for LD-LT. DCD-LTs had a 1.7-\/1.3-fold adjusted risk of losing their graft compared to DBD-LT and LD-LT, respectively (<jats:italic>p<\/jats:italic> &amp;lt; 0.010\/0.403). Bile leaks were present in 10.1% (DCD-LTs), 7.2% (DBD-LTs), and 36.2% (LD-LTs) (ORs, DBD\/LD vs. DCD: 0.7\/4.2, <jats:italic>p<\/jats:italic> = 0.402\/&amp;lt;0.001). AS developed in 28.3% DCD-LTs, 18.1% DBD-LTs, and 43.5% LD-LTs (ORs, DBD\/LD vs. DCD: 0.5\/1.8, <jats:italic>p<\/jats:italic> = 0.018\/0.006). NAS was present in 15.2% DCD-LTs, 1.4% DBDs-LT, and 4.3% LD-LTs (ORs, DBD\/LD vs. DCD: 0.1\/0.3, <jats:italic>p<\/jats:italic> = 0.001\/0.005). LTs w\/o BC had better liver graft survival compared to any other groups with BC. DCD-LT and LD-LT had excellent graft survival despite significantly higher BC rates compared to DBD-LT. DCD-LT represents a valid alternative whose importance should increase further with machine\/perfusion systems.<\/jats:p>","DOI":"10.3389\/ti.2022.10855","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T04:11:22Z","timestamp":1670559082000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":31,"title":["Comparison of Biliary Complications Rates After Brain Death, Donation After Circulatory Death, and Living-Donor Liver Transplantation: A Single-Center Cohort Study"],"prefix":"10.3389","volume":"35","author":[{"given":"Raphael Pascal Henri","family":"Meier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hillary","family":"Braun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Maluf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Freise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Ascher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garrett","family":"Roll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,12,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1914","DOI":"10.1111\/tri.13960","article-title":"Assessment 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