{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T21:55:02Z","timestamp":1788731702151,"version":"build-2803163510"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["no. 82400893"],"award-info":[{"award-number":["no. 82400893"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontierspartnerships.org"],"crossmark-restriction":true},"short-container-title":["Transpl. Int."],"abstract":"<jats:p><jats:italic>En-bloc<\/jats:italic> kidney transplantation from low-weight pediatric donors (\u22645\u00a0kg) is a challenging procedure performed only in limited transplant centers. We retrospectively analyzed the data from 42 <jats:italic>en-bloc<\/jats:italic> kidney transplants from donors weighing less than 5\u00a0kg between September 2014 and September 2023. The mean donor body weight was found to be 3.1 \u00b1 1.0\u00a0kg, and the minimum weight was 0.9\u00a0kg. At a mean follow-up period of 1,481\u00a0days, the graft survival rate was 76.2% and the recipient survival rate was 100.0%. Thrombosis and acute rejection were the major complications responsible for the short-term graft loss. Male recipients were more likely to experience graft loss than female ones (P &amp;lt; 0.05). Recipients with long-term (&amp;gt;1\u00a0year) graft survival were observed to have a high prevalence (31.3%) of delayed graft function. However, they still had satisfactory long-term graft function and limited proteinuria. Continuous graft volume growth took more than 1 year to reach a stable level. Lower donor\/recipient body surface area may lead to higher delayed graft function and slower estimated glomerular filtration rate recovery (P &amp;lt; 0.05). Kidney transplant from low-weight pediatric donors is associated with a high incidence of short-term graft loss, while long-term outcomes are generally acceptable.<\/jats:p>","DOI":"10.3389\/ti.2025.14451","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T15:59:37Z","timestamp":1748275177000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["En-Bloc Kidney Transplantation From Extremely Low-Weight (0.9\u20135.0\u00a0kg) Pediatric Donors: A Decade of Single-Center Experience"],"prefix":"10.3389","volume":"38","author":[{"given":"Xianpeng","family":"Zeng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuxiang","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhendi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,5,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1111\/j.1600-6143.2006.01353.x","article-title":"Recovery 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