{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T06:14:59Z","timestamp":1763446499175,"version":"3.45.0"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontierspartnerships.org"],"crossmark-restriction":true},"short-container-title":["Transpl. Int."],"abstract":"<jats:p>This study explores the impact of using kidneys from very-aged donors to address the organ shortage, focusing on risk factors for graft loss and delayed graft function (DGF), independent of recipient factors. Data were sourced from the French multicentric prospective DIVAT cohort and retrospectively analyzed. The study included adult recipients transplanted between 2007 and 2018 receiving kidneys from brain-deceased donors over 70. The primary endpoint was death-censored graft survival, and secondary endpoint DGF. Among 1036 patients with a median follow-up of 3.96\u00a0years (2.01\u20136.31), donor hypertension (HR 1.46 95% CI (1.09\u20131.95), cold ischemia time (HR 1.03 per hour 95% CI (1.01\u20131.06) and HLA mismatches (after adjustment on DGF, HR 1.98 (1.45\u20132.71)) were significant risk factors for graft loss. Considering DGF, donor serum creatinine (HR 1.01 95% CI (1.01\u20131.01) per \u03bcmol\/L), warm and cold ischemia times (HR 1.01 95% CI (1.0\u20131.01) per minute and HR 1.05 95% CI (1.02\u20131.08) per hour) and the use of SCOT preservation solution (HR 3.90 95% CI (1.26\u201311.84)) were deleterious, while hypothermic perfusion machine was protective (HR 0.65 95% CI (0.43\u20130.99)). The findings emphasize the paucity of modifiable variables associated with long-term outcomes in very-aged donors and the need for peri-transplant preservation strategies.<\/jats:p>","DOI":"10.3389\/ti.2025.14862","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T06:10:10Z","timestamp":1763446210000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Donor Characteristics Associated With Graft Loss and Delayed Graft Function in Very-Aged Kidney Donors: An Observational Multicentric Study"],"prefix":"10.3389","volume":"38","author":[{"given":"Mehdi","family":"Maanaoui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9mi","family":"Lenain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivien","family":"Petit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amaury","family":"Dujardin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Morelon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Charmetant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moglie","family":"Le Quintrec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Emmanuel","family":"Serre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Ladri\u00e8re","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Girerd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Masset","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Sicard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9ment","family":"Gosset","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aghil\u00e8s","family":"Hamroun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clarisse","family":"Kerleau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Garandeau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Prov\u00f4t","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magali","family":"Giral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Hazzan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Aarnink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Abdo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laetitia","family":"Albano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asma","family":"Alla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damien","family":"Ambrosetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laetitia","family":"Anquetil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lionel","family":"Badet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Ben Hassen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles","family":"Blancho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathilde","family":"Blois","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Branchereau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fanny","family":"Buron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Cantarovich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agn\u00e8s","family":"Chapelet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Charmetant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Chauvelot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Codas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Cremoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Dantal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameh","family":"Daoud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Delmas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9ment","family":"Deltombe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val\u00e9rie","family":"Dubois","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthieu","family":"Durand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Eschwege","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucile","family":"Figueres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Frimat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Garandeau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magali","family":"Giral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Girerd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Goldis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9ment","family":"Gosset","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Gourraud-Vercel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manon","family":"Gu\u00e9zennec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Hubert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Kandel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatimaezzahra","family":"Karimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clarisse","family":"Kerleau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Koenig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rapha\u00ebl","family":"Kormann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Ladriere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Lagrange","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuelle","family":"Laurain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Lecoanet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Louis","family":"Lemelle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moglie","family":"Le Quintrec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thibault","family":"Letellier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Claire","family":"Lukaszewicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Mannuguerra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Masset","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Mazeaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aur\u00e9lie","family":"Meurette","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Moreau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Morelon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Pernin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9l\u00e8ne","family":"Perrochia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Peres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maud","family":"Rabeyrin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karine","family":"Renaudin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Emmanuel","family":"Serre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Sicard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilan","family":"Szwarc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Thaunat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgo","family":"Toni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Ville","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Walencik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,11,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1920","DOI":"10.1056\/NEJMra1507080","article-title":"Improving the Supply and Quality of Deceased-Donor Organs for Transplantation","volume":"378","author":"Tullius","year":"2018","journal-title":"N Engl J Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1001\/jamainternmed.2019.2322","article-title":"Disparities in Acceptance of Deceased Donor Kidneys Between the United States and France and Estimated Effects of Increased US Acceptance","volume":"179","author":"Aubert","year":"2019","journal-title":"JAMA Intern Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1007\/s00345-023-04311-4","article-title":"Kidney Transplantation from Elderly Donors (>70 Years): A Systematic Review","volume":"41","author":"Mesnard","year":"2023","journal-title":"World J Urol"},{"key":"B4","doi-asserted-by":"crossref","DOI":"10.1002\/9780470316696","volume-title":"Multiple Imputation for Nonresponse in Surveys","author":"Rubin","year":"1987"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.3390\/jcm11051392","article-title":"Risk Factors of Rejection in Renal Transplant Recipients: A Narrative Review","volume":"11","author":"Oweira","year":"2022","journal-title":"JCM"},{"key":"B6","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/s0041-1345(02)03767-3","article-title":"Factors Affecting the Graft Survival in Cadaver Donor Kidney Transplantation","volume":"35","author":"Chon","year":"2003","journal-title":"Transplant Proc"},{"key":"B7","first-page":"397","article-title":"The UNOS Scientific Renal Transplant Registry: Multistep Regression Models on Kidney Graft Survival","author":"Cho","year":"1990","journal-title":"Clin Transpl"},{"key":"B8","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1016\/j.kint.2018.05.018","article-title":"Analyses of the Short- and Long-Term Graft Survival After Kidney Transplantation in Europe Between 1986 and 2015","volume":"94","author":"Coemans","year":"2018","journal-title":"Kidney Int"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1846","DOI":"10.1093\/ndt\/gfae081","article-title":"Better Kidney Allograft Survival Despite Higher-Risk Donor and Recipient Characteristics Between 1995 and 2014","volume":"39","author":"Ng","year":"2024","journal-title":"Nephrol Dial Transplant"},{"key":"B10","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1186\/s12882-022-02777-9","article-title":"Duration of Delayed Graft Function and Its Impact on Graft Outcomes in Deceased Donor Kidney Transplantation","volume":"23","author":"Budhiraja","year":"2022","journal-title":"BMC Nephrol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1159\/000520055","article-title":"Predictors of Delayed Graft Function in Renal Transplantation","volume":"106","author":"Kernig","year":"2022","journal-title":"Urol Int"},{"key":"B12","doi-asserted-by":"publisher","first-page":"1130","DOI":"10.1038\/ki.2014.188","article-title":"A Useful Scoring System for the Prediction and Management of Delayed Graft Function Following Kidney Transplantation from Cadaveric Donors","volume":"86","author":"Chapal","year":"2014","journal-title":"Kidney Int"},{"key":"B13","doi-asserted-by":"publisher","first-page":"3087","DOI":"10.1111\/ajt.17197","article-title":"Deceased Donor Kidneys Are Discarded at Higher Rates when Labeled as High Kidney Donor Profile Index","volume":"22","author":"Crannell","year":"2022","journal-title":"Am J Transplant"},{"key":"B14","article-title":"Rapport Rein 2021","year":"2021"},{"key":"B15","doi-asserted-by":"publisher","first-page":"S22","DOI":"10.1016\/j.ajt.2025.01.020","article-title":"OPTN\/SRTR 2023 Annual Data Report: Kidney","volume":"25","author":"Lentine","year":"2025","journal-title":"Am J Transplant"},{"key":"B16","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/j.kint.2023.05.025","article-title":"A Paired-Kidney Allocation Study Found Superior Survival with HLA-DR Compatible Kidney Transplants in the Eurotransplant Senior Program","volume":"104","author":"de Fijter","year":"2023","journal-title":"Kidney Int"},{"key":"B17","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1080\/0886022X.2021.1895838","article-title":"A Prediction Model of Delayed Graft Function in Deceased Donor for Renal Transplant: A Multi-Center Study from China","volume":"43","author":"Xue","year":"2021","journal-title":"Ren Fail"},{"key":"B18","doi-asserted-by":"publisher","first-page":"2967","DOI":"10.1097\/01.asn.0000093254.31868.85","article-title":"Nomogram for Predicting the Likelihood of Delayed Graft Function in Adult Cadaveric Renal Transplant Recipients","volume":"14","author":"Irish","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1038\/ki.2014.304","article-title":"Each Additional Hour of Cold Ischemia Time Significantly Increases the Risk of Graft Failure and Mortality Following Renal Transplantation","volume":"87","author":"Debout","year":"2015","journal-title":"Kidney Int"},{"key":"B20","doi-asserted-by":"publisher","first-page":"h3557","DOI":"10.1136\/bmj.h3557","article-title":"Long Term Outcomes of Transplantation Using Kidneys from Expanded Criteria Donors: Prospective, Population Based Cohort Study","author":"Aubert","year":"2015","journal-title":"BMJ"},{"key":"B21","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1097\/TP.0000000000003629","article-title":"Influence of Cold Ischemia Time on the Outcome of Kidney Transplants from Donors Aged 70 Years and Above\u2014A Collaborative Transplant Study Report","volume":"105","author":"Echterdiek","year":"2021","journal-title":"Transplantation"},{"key":"B22","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1016\/j.kint.2021.04.020","article-title":"Trends and Impact on Cold Ischemia Time and Clinical Outcomes Using Virtual Crossmatch for Deceased Donor Kidney Transplantation in the United States","volume":"100","author":"Puttarajappa","year":"2021","journal-title":"Kidney Int"},{"key":"B23","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1097\/TP.0000000000000844","article-title":"Logistical Factors Influencing Cold Ischemia Times in Deceased Donor Kidney Transplants","volume":"100","author":"Shrestha","year":"2016","journal-title":"Transplantation"},{"key":"B24","doi-asserted-by":"publisher","first-page":"e936514","DOI":"10.12659\/aot.936514","article-title":"Evaluation of Deceased Donor Kidney Transplantation in the Eurotransplant Senior Program in Comparison to Standard Allocation","volume":"27","author":"Eklou","year":"2022","journal-title":"Ann Transpl"},{"key":"B25","doi-asserted-by":"publisher","first-page":"e0235680","DOI":"10.1371\/journal.pone.0235680","article-title":"Comparison of Kidney Allograft Survival in the Eurotransplant Senior Program After Changing the Allocation Criteria in 2010\u2014A Single Center Experience","volume":"15","author":"Mehdorn","year":"2020","journal-title":"PLoS ONE"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.6002\/ect.2021.0129","article-title":"The New UK National Kidney Allocation Scheme with Maximized \u201cR4-D4\u201d Kidney Transplants: Better Patient-to-Graft Longevity Matching May Be at the Cost of More Resources","volume":"19","author":"Pearson","year":"2021","journal-title":"Exp Clin Transpl"},{"key":"B27","article-title":"POL186\/21 \u2013 Kidney Transplantation: Deceased Donor Organ Allocation","year":"2025"},{"key":"B28","doi-asserted-by":"publisher","first-page":"2647","DOI":"10.1111\/j.1600-6143.2011.03741.x","article-title":"Impact of Cold Ischemia Time on Graft Survival Among ECD Transplant Recipients: A Paired Kidney Analysis","volume":"11","author":"Kayler","year":"2011","journal-title":"Am J Transplant"},{"key":"B29","doi-asserted-by":"publisher","first-page":"20543581231178960","DOI":"10.1177\/20543581231178960","article-title":"The Impact of Combined Warm and Cold Ischemia Time on Post-Transplant Outcomes","volume":"10","author":"Foley","year":"2023","journal-title":"Can J Kidney Health Dis"},{"key":"B30","doi-asserted-by":"publisher","first-page":"4395","DOI":"10.3390\/jcm10194395","article-title":"Influence of Multiple Donor Renal Arteries on the Outcome and Graft Survival in Deceased Donor Kidney Transplantation","volume":"10","author":"Scheuermann","year":"2021","journal-title":"JCM"},{"key":"B31","doi-asserted-by":"publisher","first-page":"432","DOI":"10.12659\/AOT.916012","article-title":"Implantation Warm Ischemia Time in Kidney Transplant Recipients: Defining Its Limits and Impact on Early Graft Function","volume":"24","author":"Khan","year":"2019","journal-title":"Ann Transpl"},{"key":"B32","doi-asserted-by":"publisher","first-page":"12226","DOI":"10.1038\/s41598-021-91843-7","article-title":"Impaired Renal Function Before Kidney Procurement Has a Deleterious Impact on Allograft Survival in Very Old Deceased Kidney Donors","volume":"11","author":"Maanaoui","year":"2021","journal-title":"Sci Rep"},{"key":"B33","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1053\/j.ajkd.2021.06.022","article-title":"Association Between Deceased Donor Acute Kidney Injury Assessed Using Baseline Serum Creatinine Back-Estimation and Graft Survival: Results from the French National CRISTAL Registry","volume":"79","author":"Lenain","year":"2022","journal-title":"Am J Kidney Dis"},{"key":"B34","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1056\/NEJMoa0802289","article-title":"Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation","volume":"360","author":"Moers","year":"2009","journal-title":"N Engl J Med"},{"key":"B35","doi-asserted-by":"publisher","first-page":"3426","DOI":"10.1111\/ajt.15995","article-title":"Effect of Preservation Solutions for Static Cold Storage on Kidney Transplantation Outcomes: A National Registry Study","volume":"20","author":"Legeai","year":"2020","journal-title":"Am J Transplant"},{"key":"B36","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1038\/s41591-023-02376-7","article-title":"Normothermic Machine Perfusion Versus Static Cold Storage in Donation After Circulatory Death Kidney Transplantation: A Randomized Controlled Trial","volume":"29","author":"Hosgood","year":"2023","journal-title":"Nat Med"},{"key":"B37","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1056\/nejmoa2118265","article-title":"Hypothermia or Machine Perfusion in Kidney Donors","volume":"388","author":"Malinoski","year":"2023","journal-title":"N Engl J Med"},{"key":"B38","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/S0140-6736(23)00642-6","article-title":"Balanced Crystalloid Solution Versus Saline in Deceased Donor Kidney Transplantation (BEST-Fluids): A Pragmatic, Double-Blind, Randomised, Controlled Trial","volume":"402","author":"Collins","year":"2023","journal-title":"The Lancet"}],"container-title":["Transplant International"],"original-title":[],"link":[{"URL":"https:\/\/www.frontierspartnerships.org\/articles\/10.3389\/ti.2025.14862\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T06:10:11Z","timestamp":1763446211000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontierspartnerships.org\/articles\/10.3389\/ti.2025.14862\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,18]]},"references-count":38,"alternative-id":["10.3389\/ti.2025.14862"],"URL":"https:\/\/doi.org\/10.3389\/ti.2025.14862","relation":{},"ISSN":["1432-2277"],"issn-type":[{"value":"1432-2277","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,18]]},"article-number":"14862"}}