{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:08:09Z","timestamp":1792523289465,"version":"4.5.0"},"reference-count":106,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontierspartnerships.org"],"crossmark-restriction":true},"short-container-title":["Transpl. Int."],"abstract":"<jats:p>Since the first live birth in 2014 after uterus transplantation, the procedure has become a viable fertility treatment worldwide for the 1 in 500 women affected by absolute uterine factor infertility. In this review, we provide insight on Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH) and the other conditions that lead to the development of AUFI. Additionally, we provide a comprehensive overview of the evolution of uterus transplantation from the first sporadic cases to the current clinical status of the procedure, and detail multiple aspects that go into a successful UTx. 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