{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:21:48Z","timestamp":1787808108611,"version":"build-2784847793"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontierspartnerships.org"],"crossmark-restriction":true},"short-container-title":["Transpl. Int."],"abstract":"<jats:p>Outcomes of kidney-alone transplantation (KAT) in former simultaneous liver-kidney (SLK) transplant candidates after liver waitlist delisting are not well defined. Using Scientific Registry of Transplant Recipients (SRTR) data, we identified adult recipients who underwent KAT between 2005 and 2025 after prior SLK listing (RLD-KAT), which was matched 1:5 to primary KAT recipients without liver disease by age, transplant year, and diabetes status. Patient and graft survival were evaluated using the Kaplan-Meier method and multivariable Cox proportional hazards models. We identified 163 RLD-KAT recipients matched to 815 controls. Unadjusted Kaplan-Meier analyses demonstrated lower patient survival in RLD-KAT (p = 0.020), whereas death-censored and overall graft survival were similar (p &amp;gt; 0.05). In multivariable models, death-censored graft survival (HR 0.89; 95% CI 0.51\u20131.53), overall graft survival (HR 1.00; 95% CI 0.73\u20131.36), and patient survival (HR 1.07; 95% CI 0.76\u20131.5) did not differ significantly. Six RLD-KAT recipients (3.7%) subsequently underwent liver transplantation. Kidney-alone transplantation in prior SLK candidates was associated with acceptable patient and graft outcomes and a low incidence of subsequent liver transplantation.<\/jats:p>","DOI":"10.3389\/ti.2026.16834","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:10:08Z","timestamp":1787807408000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Kidney-alone transplantation in prior SLK candidates: a national registry analysis"],"prefix":"10.3389","volume":"39","author":[{"given":"Beat","family":"Moeckli","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Geneva","place":["Geneva, Switzerland"]},{"name":"Division of Gastroenterology, Department of Medicine, Henry Ford Health","place":["Detroit, MI, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin B.","family":"Harris","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Medicine, Henry Ford Health","place":["Detroit, MI, United States"]},{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byron","family":"Smith","sequence":"additional","affiliation":[{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Pereyra","sequence":"additional","affiliation":[{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiomara","family":"Benavides","sequence":"additional","affiliation":[{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jody","family":"Olson","sequence":"additional","affiliation":[{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander R.","family":"Cortez","sequence":"additional","affiliation":[{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timucin","family":"Taner","sequence":"additional","affiliation":[{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie K.","family":"Heimbach","sequence":"additional","affiliation":[{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas A.","family":"Simonetto","sequence":"additional","affiliation":[{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samy M.","family":"Riad","sequence":"additional","affiliation":[{"name":"Transplant Center, Mayo Clinic Minnesota","place":["Rochester, MN, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1002\/lt.25694","article-title":"Chronic kidney disease in liver transplant candidates: a rising burden impacting post-liver transplant outcomes","volume":"26","author":"Cullaro","year":"2020","journal-title":"Liver Transpl"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2515","DOI":"10.1111\/tri.14158","article-title":"A meta-analysis on the prevalence of chronic kidney disease in liver transplant candidates and its associated risk factors and outcomes","volume":"34","author":"Teo","year":"2021","journal-title":"Transpl Int"},{"key":"B3","doi-asserted-by":"publisher","first-page":"S193","DOI":"10.1016\/j.ajt.2025.01.022","article-title":"OPTN\/SRTR 2023 annual data report: liver","volume":"25","author":"Kwong","year":"2025","journal-title":"Am J Transpl"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.1111\/liv.13151","article-title":"The clinical course of alcoholic cirrhosis: development of comorbid diseases. 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