{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T20:31:24Z","timestamp":1776976284851,"version":"3.51.4"},"reference-count":237,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:00:00Z","timestamp":1670457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"<jats:p>Over the past few decades, natural-origin polysaccharides have received increasing attention across different fields of application, including biomedicine and biotechnology, because of their specific physicochemical and biological properties that have afforded the fabrication of a plethora of multifunctional devices for healthcare applications. More recently, marine raw materials from fisheries and aquaculture have emerged as a highly sustainable approach to convert marine biomass into added-value polysaccharides for human benefit. Nowadays, significant efforts have been made to combine such circular bio-based approach with cost-effective and environmentally-friendly technologies that enable the isolation of marine-origin polysaccharides up to the final construction of a biomedical device, thus developing an entirely sustainable pipeline. In this regard, the present review intends to provide an up-to-date outlook on the current green extraction methodologies of marine-origin polysaccharides and their molecular engineering toolbox for designing a multitude of biomaterial platforms for healthcare. Furthermore, we discuss how to foster circular bio-based approaches to pursue the further development of added-value biomedical devices, while preserving the marine ecosystem.<\/jats:p>","DOI":"10.3389\/fbioe.2022.1041102","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T12:03:44Z","timestamp":1670501024000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":35,"title":["Green approaches for extraction, chemical modification and processing of marine polysaccharides for biomedical applications"],"prefix":"10.3389","volume":"10","author":[{"given":"Margarida M. A.","family":"Sacramento","sequence":"first","affiliation":[]},{"given":"Jo\u00e3o","family":"Borges","sequence":"additional","affiliation":[]},{"given":"Fernando J. S.","family":"Correia","sequence":"additional","affiliation":[]},{"given":"Ricardo","family":"Calado","sequence":"additional","affiliation":[]},{"given":"Jo\u00e3o M. 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