{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:24:12Z","timestamp":1762161852146,"version":"3.41.2"},"reference-count":72,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T00:00:00Z","timestamp":1722297600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Biomater. Sci."],"abstract":"<jats:p>Correlated Multimodal Imaging (CMI) gathers information about the same specimen with two or more modalities that\u2013combined\u2013create a composite and complementary view of the sample (including insights into structure, function, dynamics and molecular composition). CMI allows one to reach beyond what is possible with a single modality and describe biomedical processes within their overall spatio-temporal context and gain a mechanistic understanding of cells, tissues, and organisms in health and disease by untangling their molecular mechanisms within their native environment. The field of CMI has grown substantially over the last decade and previously unanswerable biological questions have been solved by applying novel CMI workflows. To disseminate these workflows and comprehensively share the scattered knowledge present within the CMI community, an initiative was started to bring together imaging, image analysis, and biomedical scientists and work towards an open community that promotes and disseminates the field of CMI. This community project was funded for the last 4 years by an EU COST Action called COMULIS (COrrelated MUltimodal imaging in the LIfe Sciences). In this review we share some of the showcases and lessons learnt from the action. We also briefly look ahead at how we anticipate building on this initial initiative.<\/jats:p>","DOI":"10.3389\/fbiom.2024.1338115","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T04:21:06Z","timestamp":1722313266000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Correlated multimodal imaging in life sciences: lessons learnt"],"prefix":"10.3389","volume":"3","author":[{"given":"Pavitra Sokke","family":"Rudraiah","sequence":"first","affiliation":[]},{"given":"Rafael","family":"Camacho","sequence":"additional","affiliation":[]},{"given":"Julia","family":"Fernandez-Rodriguez","sequence":"additional","affiliation":[]},{"given":"Dror","family":"Fixler","sequence":"additional","affiliation":[]},{"given":"Jan","family":"Grimm","sequence":"additional","affiliation":[]},{"given":"Florian","family":"Gruber","sequence":"additional","affiliation":[]},{"given":"Mat\u00fa\u0161","family":"Kala\u0161","sequence":"additional","affiliation":[]},{"given":"Christopher","family":"Kremslehner","sequence":"additional","affiliation":[]},{"given":"Claudia","family":"Kuntner","sequence":"additional","affiliation":[]},{"given":"Daniela","family":"Kuzdas-Wood","sequence":"additional","affiliation":[]},{"given":"Joakim","family":"Lindblad","sequence":"additional","affiliation":[]},{"given":"Julia G.","family":"Mannheim","sequence":"additional","affiliation":[]},{"given":"Martina","family":"Marchetti-Deschmann","sequence":"additional","affiliation":[]},{"given":"Perrine","family":"Paul-Gilloteaux","sequence":"additional","affiliation":[]},{"given":"Paula","family":"Sampaio","sequence":"additional","affiliation":[]},{"given":"Peter","family":"Sandbichler","sequence":"additional","affiliation":[]},{"given":"Anna","family":"Sartori-Rupp","sequence":"additional","affiliation":[]},{"given":"Nata\u0161a","family":"Sladoje","sequence":"additional","affiliation":[]},{"given":"Paul","family":"Verkade","sequence":"additional","affiliation":[]},{"given":"Andreas","family":"Walter","sequence":"additional","affiliation":[]},{"given":"Samuele","family":"Zoratto","sequence":"additional","affiliation":[]}],"member":"1965","published-online":{"date-parts":[[2024,7,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jmsacl.2021.12.006","article-title":"An overview of image registration for aligning mass spectrometry imaging with clinically relevant imaging modalities","volume":"23","author":"Balluff","year":"2022","journal-title":"J. Mass Spectrom. Adv. Clin. Lab"},{"key":"B2","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1142\/S1793545811001319","article-title":"Optical properties of skin, subcutaneous and muscle tissues: a review","volume":"4","author":"Bashkatov","year":"2011","journal-title":"J. Innov. Opt. Health Sci."},{"key":"B3","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1111\/j.1747-4949.2009.00386.x","article-title":"Emulating multicentre clinical stroke trials: a new paradigm for studying novel interventions in experimental models of stroke","volume":"4","author":"Bath","year":"2009","journal-title":"Int. J. Stroke"},{"key":"B4","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.dyepig.2019.04.018","article-title":"Unraveling the real pigment composition of tattoo inks: the case of bi-components phthalocyanine based greens","volume":"167","author":"Bauer","year":"2019","journal-title":"Dyes Pigments"},{"key":"B5","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1161\/CIRCRESAHA.114.303819","article-title":"Reproducibility in science: improving the standard for basic and preclinical research","volume":"116","author":"Begley","year":"2015","journal-title":"Circ. Res."},{"key":"B6","doi-asserted-by":"publisher","first-page":"377","DOI":"10.12968\/joan.2019.8.8.377","article-title":"An insight into laser tattoo removal: reasoning, methods and limitations","volume":"8","author":"Boardman","year":"2019","journal-title":"J Aesthetic Nurs."},{"key":"B7","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1039\/C6JA00210B","article-title":"Size and metal composition characterization of nano-and microparticles in tattoo inks by a combination of analytical techniques","volume":"32","author":"Bocca","year":"2017","journal-title":"J. Anal. A. T. Spectrom."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1109\/ISBI.2016.7493463","article-title":"Robust registration of calcium images by learned contrast synthesis","author":"Bogovic","year":"2016","journal-title":"Biomed. Imaging (ISBI)"},{"key":"B9","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1007\/s10103-023-03842-x","article-title":"Selected abstracts from the 40th annual conference of the British medical laser association: BMLA 2023 annual conference","volume":"38","year":"2023","journal-title":"Lasers Med. Sci."},{"key":"B10","doi-asserted-by":"publisher","first-page":"2166","DOI":"10.1109\/3.64354","article-title":"A review of the optical properties of biological tissues","volume":"26","author":"Cheong","year":"1990","journal-title":"IEEE J. Quant. Electr."},{"key":"B11","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1038\/s41592-023-01861-8","article-title":"Volume EM: a quiet revolution takes shape","volume":"20","author":"Collinson","year":"2023","journal-title":"Nat. Methods"},{"key":"B12","doi-asserted-by":"publisher","first-page":"2322","DOI":"10.1007\/s10278-023-00800-5","article-title":"Correction to: lossy image compression in a preclinical multimodal imaging study","volume":"36","author":"Cunha","year":"2023","journal-title":"J. Digit. Imaging"},{"key":"B13","doi-asserted-by":"publisher","first-page":"4990","DOI":"10.1039\/c8an01213j","article-title":"Confocal Raman microscopy combined with optical clearing for identification of inks in multicolored tattooed skin in vivo","volume":"143","author":"Darvin","year":"2018","journal-title":"Analyst"},{"key":"B14","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1038\/d41586-023-00178-y","article-title":"Seven technologies to watch in 2023","volume":"613","author":"Eisenstein","year":"2023","journal-title":"Nature"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1080\/00032719.2023.2237141","article-title":"Determination of selected elements in commercially available tattoo inks of the Greek market using atomic absorption spectrometry","volume":"57","author":"Evgenakis","year":"2023","journal-title":"At. Spectrosc."},{"key":"B16","doi-asserted-by":"publisher","first-page":"155011","DOI":"10.1088\/1361-6560\/ac7e17","article-title":"Deformable image registration with deep network priors: a study on longitudinal PET images","volume":"67","author":"Fourcade","year":"2022","journal-title":"Phys. Med. Biol."},{"key":"B17","first-page":"999","article-title":"Impact of animal handling on the results of 18F-FDG PET studies in mice","volume":"47","author":"Fueger","year":"2006","journal-title":"J. Nucl. Med."},{"key":"B18","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s11307-019-01368-9","article-title":"Quantitative rodent brain receptor imaging","volume":"22","author":"Herfert","year":"2020","journal-title":"Mol. Imaging Biol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"eaaz5357","DOI":"10.1126\/science.aaz5357","article-title":"Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells","volume":"367","author":"Hoffman","year":"2020","journal-title":"Science"},{"key":"B20","doi-asserted-by":"publisher","first-page":"8831","DOI":"10.1021\/acs.analchem.8b00816","article-title":"Multisensor imaging\u2014from sample preparation to integrated multimodal interpretation of LA-ICPMS and MALDI MS imaging data","volume":"90","author":"Holzlechner","year":"2018","journal-title":"Anal. Chem."},{"key":"B21","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1093\/bioinformatics\/btt113","article-title":"EDAM: an ontology of bioinformatics operations, types of data and identifiers, topics and formats","volume":"29","author":"Ison","year":"2013","journal-title":"Bioinformatics"},{"key":"B22","doi-asserted-by":"publisher","first-page":"100722","DOI":"10.1016\/j.xpro.2021.100722","article-title":"Visualizing murine breast and melanoma tumor microenvironment using intravital multiphoton microscopy","volume":"2","author":"Jain","year":"2023","journal-title":"Star. Protoc."},{"key":"B23","doi-asserted-by":"publisher","first-page":"162","DOI":"10.7490\/f1000research.1117826.1","article-title":"EDAM-bioimaging: the ontology of bioimage informatics operations, topics, data, and formats (update 2020) [version 1; not peer reviewed]","volume":"9","author":"Kala\u0161","year":"2020","journal-title":"F1000Research"},{"key":"B24","doi-asserted-by":"publisher","first-page":"1918","DOI":"10.3390\/biomedicines9121918","article-title":"High-resolution episcopic microscopy (HREM) in multimodal imaging approaches","volume":"9","author":"Keuenhof","year":"2021","journal-title":"Biomedicines"},{"key":"B25","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/bs.mcb.2020.10.002","article-title":"Multimodality imaging beyond CLEM: showcases of combined in-vivo preclinical imaging and ex-vivo microscopy to detect murine mural vascular lesions","volume":"162","author":"Keuenhofer","year":"2021","journal-title":"Meth Cell Biol."},{"key":"B26","article-title":"Synchronization to visualization: dissecting myogenesis and regeneration using correlative light and electron microscopy (CLEM)","volume-title":"Bioimaging in tissue engineering and regeneration. Reference series in biomedical engineering","author":"Khan","year":"2023"},{"key":"B27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1109\/SIU55565.2022.9864739","article-title":"Pigment boundary and depth determination technique for photoacoustic microscopy image of tissue","volume-title":"2022 30th signal processing and communications applications conference (SIU)","author":"K\u00f6ksal","year":"2022"},{"key":"B28","doi-asserted-by":"publisher","first-page":"101583","DOI":"10.1016\/j.redox.2020.101583","article-title":"Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents - implications for oxidative UV damage","volume":"37","author":"Kremslehner","year":"2020","journal-title":"Redox Biol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"026004","DOI":"10.1117\/1.JBO.27.2.026004","article-title":"Skin chromophore mapping by smartphone RGB camera under spectral band and spectral line illumination","volume":"27","author":"Kuzmina","year":"2022","journal-title":"J. Biomed. Opt."},{"key":"B30","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1111\/j.1365-4362.1987.tb00590.x","article-title":"Human tattoo electron microscopic assessment of epidermis, epidermal-dermal junction, and dermis","volume":"26","author":"Lea","year":"1987","journal-title":"Int. J. Dermatol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/bs.mcb.2017.03.007","article-title":"Correlative two-photon and serial block face scanning electron microscopy in neuronal tissue using 3D near-infrared branding maps","volume":"140","author":"Lees","year":"2017","journal-title":"Methods Cell Biol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1093\/jnci\/djt209","article-title":"From bench to bedside: lessons learned in translating preclinical studies in cancer drug development","volume":"105","author":"Lieu","year":"2013","journal-title":"J. Natl. Cancer Inst."},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.7490\/f1000research.1117826.1","article-title":"EDAM Bioimaging: the ontology of (bio-)image informatics and machine learning","volume":"6","author":"Lindblad","year":"2020","journal-title":"Zenodo Versions alpha"},{"key":"B34","doi-asserted-by":"publisher","first-page":"e0276196","DOI":"10.1371\/journal.pone.0276196","article-title":"Is image-to-image translation the panacea for multimodal image registration? A comparative study","volume":"17","author":"Lu","year":"2022","journal-title":"PLoS One"},{"key":"B35","doi-asserted-by":"publisher","first-page":"e202000097","DOI":"10.1002\/jbio.202000097","article-title":"STED nanoscopy of KK114-stained pathogenic bacteria","volume":"13","author":"Lucidi","year":"2020","journal-title":"J. Biophot."},{"key":"B36","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.2967\/jnumed.118.221994","article-title":"Reproducibility and comparability of preclinical PET imaging data: a multicenter small-animal PET study","volume":"60","author":"Mannheim","year":"2019","journal-title":"J. Nucl. Med."},{"key":"B37","doi-asserted-by":"publisher","first-page":"p1395","DOI":"10.1093\/bioinformatics\/btw013","article-title":"Collaborative analysis of multi-gigapixel imaging data using Cytomine","volume":"32","author":"Mar\u00e9e","year":"2016","journal-title":"Bioinformatics"},{"key":"B38","doi-asserted-by":"publisher","first-page":"jnumed.119.231308","DOI":"10.1007\/s11307-018-01305-2","article-title":"Standardization of preclinical PET\/CT imaging to improve quantitative accuracy, precision and reproducibility: a multi-center study","author":"McDougald","year":"2019","journal-title":"J. Nucl. Med."},{"key":"B39","doi-asserted-by":"publisher","first-page":"2286","DOI":"10.1038\/jid.2010.115","article-title":"Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model","volume":"130","author":"Mildner","year":"2010","journal-title":"J. Invest. Dermatol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"1496","DOI":"10.1038\/s41592-021-01326-w","article-title":"OME-NGFF: a next-generation file format for expanding bioimaging data-access strategies","volume":"18","author":"Moore","year":"2021","journal-title":"Nat. Methods"},{"key":"B41","doi-asserted-by":"publisher","first-page":"3906","DOI":"10.1021\/acs.analchem.3c05687","article-title":"What\u2019s in my ink: an analysis of commercial tattoo ink on the US market","volume":"96","author":"Moseman","year":"2024","journal-title":"Anal. Chem."},{"key":"B42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/jemt.24548","article-title":"Automated segmentation of cell organelles in volume electron microscopy using deep learning","author":"Ne\u0161ic","year":"2024","journal-title":"Microsc. Res. Tech."},{"key":"B43","first-page":"1","article-title":"Contrastive learning of equivariant image representations for multimodal deformable registration","volume-title":"IEEE 20th international symposium on biomedical imaging","author":"Nordling","year":"2023"},{"key":"B44","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.patrec.2022.05.022","article-title":"Fast computation of mutual information in the frequency domain with applications to global multimodal image alignment","volume":"159","author":"\u00d6fverstedt","year":"2022","journal-title":"Pattern Recognit. Lett."},{"key":"B45","first-page":"128","article-title":"Deep learning vs. Traditional computer vision","volume-title":"Advances in computer vision. CVC. Advances in intelligent systems and computing","author":"O\u2019Mahony","year":"2019"},{"key":"B46","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1038\/s41584-021-00627-w","article-title":"Striking a balance in rheumatoid arthritis prevention trials","volume":"17","author":"O\u2019Neil","year":"2021","journal-title":"Nat. Rev. Rheumat"},{"key":"B47","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1007\/s11307-016-1012-3","article-title":"Guidance for efficient small animal imaging quality control","volume":"19","author":"Osborne","year":"2017","journal-title":"Mol. Imaging Biol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/s41592-023-01776-4","article-title":"MoBIE: a Fiji plugin for sharing and exploration of multi-modal cloud-hosted big image data","volume":"20","author":"Pape","year":"2023","journal-title":"Nat. Methods"},{"key":"B49","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1038\/nmeth.4170","article-title":"eC-CLEM: flexible multidimensional registration software for correlative microscopies","volume":"14","author":"Paul-Gilloteaux","year":"2017","journal-title":"Nat. Methods"},{"key":"B50","doi-asserted-by":"publisher","first-page":"320","DOI":"10.12688\/f1000research.52569.1","article-title":"Bioimage analysis workflows: community resources to navigate through a complex ecosystem","volume":"10","author":"Paul-Gilloteaux","year":"2021","journal-title":"F1000Res"},{"key":"B51","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1038\/s43586-022-00131-9","article-title":"Volume electron microscopy","volume":"2","author":"Peddie","year":"2022","journal-title":"Nat. Rev. Methods Prim."},{"key":"B52","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1038\/nrd3849","article-title":"In search of preclinical robustness","volume":"11","author":"Peers","year":"2012","journal-title":"Nat. Rev. Drug Discov."},{"key":"B53","doi-asserted-by":"publisher","first-page":"18433","DOI":"10.48550\/arXiv.2006.06325","article-title":"CoMIR: contrastive multimodal image representation for registration","volume":"33","author":"Pielawski","year":"2020","journal-title":"Adv. Neural Inf. Process. Syst."},{"key":"B54","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1083\/jcb.148.1.45","article-title":"Correlative light-electron microscopy reveals the tubular-saccular ultrastructure of carriers operating between Golgi apparatus and plasma membrane","volume":"148","author":"Polishchuk","year":"2000","journal-title":"J. Cell Biol."},{"key":"B55","doi-asserted-by":"publisher","first-page":"4683","DOI":"10.1039\/D0AN02373F","article-title":"Cross-modality imaging of bisphosphonate-treated murine jawbones","volume":"14","author":"Reier","year":"2021","journal-title":"Analyst"},{"key":"B56","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.remn.2016.06.001","article-title":"Simultaneous PET\/MRI vs PET\/CT in oncology. A systematic review","volume":"35","author":"Riola-Parada","year":"2016","journal-title":"Rev. Esp. Med. Nucl. Imagen Mol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"117001","DOI":"10.1117\/1.JBO.26.11.117001","article-title":"Bottom layer absorption coefficients extraction from two-layer phantoms based on crossover point in diffuse reflectance","volume":"26","author":"Rudraiah","year":"2021","journal-title":"J. Biomed. Opt."},{"key":"B58","doi-asserted-by":"crossref","DOI":"10.1117\/12.2608530","article-title":"Extraction of absorption coefficients from two-layer phantoms based on crossover point in diffuse reflectance","volume-title":"Proceedings volume 11976, nanoscale imaging, sensing and actuation for biomedical applications XIX","author":"Rudraiah","year":""},{"key":"B59","doi-asserted-by":"publisher","first-page":"e202200003","DOI":"10.1002\/jbio.202200003","article-title":"Diffused reflectance measurements to detect tattoo ink location in skin using the crossover point","volume":"15","author":"Rudraiah","year":"","journal-title":"J. Biophot."},{"key":"B60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1109\/JSTQE.2022.3208570","article-title":"Deep tattoo ink depth profiling in ex vivo porcine skin using diffuse reflectance spectroscopy","volume":"29","author":"Rudraiah","year":"","journal-title":"IEEE Xplore"},{"key":"B61","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"B62","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.freeradbiomed.2017.01.029","article-title":"Sunlight damage to cellular DNA: focus on oxidatively generated lesions","volume":"107","author":"Schuch","year":"2017","journal-title":"Free Radic. Biol. Med."},{"key":"B63","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/bs.mcb.2020.12.001","article-title":"The Histo-CLEM Workflow for tissues of model organisms","volume":"162","author":"Sousa","year":"2021","journal-title":"Methods Cell Biol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"5007","DOI":"10.1088\/0031-9155\/58\/14\/5007","article-title":"Corrigendum: optical properties of biological tissues: a review","volume":"58","author":"Steven","year":"2013","journal-title":"Phys. Med. Biol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1935","DOI":"10.1016\/j.bpj.2019.10.001","article-title":"Homo- and heteroassociations drive activation of ErbB3","volume":"117","author":"V\u00e1radi","year":"2019","journal-title":"Biophysical J."},{"key":"B66","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/bs.mcb.2020.12.010","article-title":"Correlated multimodal imaging: building a community","volume":"162","author":"Walter","year":"","journal-title":"Methods Cell Biol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"541p","DOI":"10.1088\/978-0-7503-3059-6","article-title":"Imaging modalities for biological and preclinical research: a compendium, volume 1, Part I: ex vivo biological imaging","author":"Walter","year":"","journal-title":"IOP Sci."},{"key":"B68","doi-asserted-by":"crossref","DOI":"10.1088\/978-0-7503-3747-2ch31","article-title":"Emerging technologies and outlook","volume-title":"Imaging modalities for biological and preclinical research: a compendium, volume 2, parts II-IV","author":"Walter","year":""},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.3389\/fphy.2020.00047","article-title":"Correlated multimodal imaging in life sciences: expanding the biomedical horizon","volume":"8","author":"Walter","year":"2020","journal-title":"Front. Phys."},{"key":"B70","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1007\/978-3-030-42618-7_22","article-title":"Clinical PET\/MR","volume":"216","author":"Weber","year":"2020","journal-title":"Recent Results Cancer Res."},{"key":"B71","doi-asserted-by":"publisher","first-page":"dmm043091","DOI":"10.1242\/dmm.043091","article-title":"The zebrafish as a novel model for the in vivo study of Toxoplasma gondii replication and interaction with macrophages","volume":"20","author":"Yoshida","year":"2020","journal-title":"Dis. Model Mech."},{"key":"B72","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1002\/lsm.23720","article-title":"Objective monitoring of laser tattoo removal in human volunteers using an innovative optical technique: a proof of principle","volume":"55","author":"Zima","year":"2023","journal-title":"Lasers Surg. Med."}],"container-title":["Frontiers in Biomaterials Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fbiom.2024.1338115\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T04:21:17Z","timestamp":1722313277000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fbiom.2024.1338115\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,30]]},"references-count":72,"alternative-id":["10.3389\/fbiom.2024.1338115"],"URL":"https:\/\/doi.org\/10.3389\/fbiom.2024.1338115","relation":{},"ISSN":["2813-3749"],"issn-type":[{"type":"electronic","value":"2813-3749"}],"subject":[],"published":{"date-parts":[[2024,7,30]]},"article-number":"1338115"}}