{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T20:41:39Z","timestamp":1774471299437,"version":"3.50.1"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T00:00:00Z","timestamp":1743638400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Digit. Health"],"abstract":"<jats:p>Artificial intelligence (AI) 's rapid integration into healthcare transforms medical decision-making, preventive strategies, and patient engagement. AI-driven technologies, including real-time health monitoring and predictive analytics, offer new personalized preventive care possibilities. However, concerns regarding ethical implications, data security, and equitable access remain unresolved. This paper addresses the critical gap in AI integration in preventive healthcare, highlighting statistical evidence of its impact. It also explores the intersection of AI, preventive medicine, and ethical challenges in future healthcare, envisioning the evolving roles of physicians and patients in an AI-integrated ecosystem. A fictional case study projected for 2040, illustrating an entirely digitized, AI-supported healthcare system, frames the discussion about digital health technologies, privacy regulations, and AI's ethical implications in the future of preventive medicine. Digital health interventions powered by AI will facilitate real-time preventive strategies, strengthen patient autonomy, and enhance precision medicine. However, algorithmic bias, data privacy, and healthcare equity challenges must be addressed to ensure AI fosters inclusivity rather than exacerbating disparities. Regulatory frameworks, such as GDPR, provide foundational protections, but further adaptations are required to govern AI's expanding role in medicine. This digital-assisted preventive medicine has the potential to redefine patient-provider interactions, enhance healthcare efficiency, and promote proactive health management. However, achieving this vision requires a multidisciplinary approach involving health professionals, policymakers, and technology developers. Future research should focus on regulatory strategies, digital literacy, and ethical AI implementation to balance innovation with equity, ensuring that digital healthcare remains patient-centered and inclusive.<\/jats:p>","DOI":"10.3389\/fdgth.2025.1588479","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T05:57:39Z","timestamp":1743659859000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["The doctor and patient of tomorrow: exploring the intersection of artificial intelligence, preventive medicine, and ethical challenges in future healthcare"],"prefix":"10.3389","volume":"7","author":[{"given":"Paulo","family":"Santos","sequence":"first","affiliation":[]},{"given":"Isabel","family":"Nazar\u00e9","sequence":"additional","affiliation":[]}],"member":"1965","published-online":{"date-parts":[[2025,4,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2024.101145","article-title":"Benefits and harms associated with the use of AI-related algorithmic decision-making systems by healthcare professionals: a systematic review","volume":"48","author":"Wilhelm","year":"2025","journal-title":"Lancet Reg Health Eur"},{"key":"B2","article-title":"Regulation (EU) 2021\/2282 of the European Parliament and of the Council of 15 December 2021 on health technology assessment and amending Directive 2011\/24\/EU (OJ L 458, 22.12.2021, pp. 1\u201332)","year":""},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.40969","article-title":"Large language model influence on diagnostic reasoning","volume":"7","author":"Goh","year":"2024","journal-title":"JAMA Netw Open"},{"key":"B4","volume-title":"Health at a Glance: Europe 2024: State of Health in the EU Cycle","year":"2024"},{"key":"B5","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1080\/09540121.2021.1948499","article-title":"Utilizing big data analytics and electronic health record data in HIV prevention, treatment, and care research: a literature review","volume":"36","author":"Qiao","year":"2021","journal-title":"AIDS Care"},{"key":"B6","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.trecan.2023.10.006","article-title":"Big data and artificial intelligence in cancer research","volume":"10","author":"Wu","year":"2024","journal-title":"Trends Cancer"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-024-01103-x","article-title":"A systematic review and meta-analysis of artificial intelligence versus clinicians for skin cancer diagnosis","volume":"7","author":"Salinas","year":"2024","journal-title":"NPJ Digit Med"},{"key":"B8","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1038\/s41746-021-00418-3","article-title":"The emerging clinical role of wearables: factors for successful implementation in healthcare","volume":"4","author":"Smuck","year":"2021","journal-title":"NPJ Digit Med"},{"key":"B9","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1007\/s11606-011-1931-2","article-title":"Why does patient activation matter? 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