{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T12:16:38Z","timestamp":1752668198635,"version":"3.37.3"},"reference-count":50,"publisher":"Frontiers Media SA","funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["PEst-OE\/BIA\/UI4046\/2014; UID\/MULTI\/04046\/2013; SFRH\/BPD\/63619\/2009; SFRH\/BPD\/81635\/2011"],"award-info":[{"award-number":["PEst-OE\/BIA\/UI4046\/2014; UID\/MULTI\/04046\/2013; SFRH\/BPD\/63619\/2009; SFRH\/BPD\/81635\/2011"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Plant Sci."],"DOI":"10.3389\/fpls.2015.00816","type":"journal-article","created":{"date-parts":[[2015,10,6]],"date-time":"2015-10-06T12:51:52Z","timestamp":1444135912000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Ion and lipid signaling in apical growth\u2014a dynamic machinery responding to extracellular cues"],"prefix":"10.3389","volume":"6","author":[{"given":"Rui","family":"Malh\u00f3","sequence":"first","affiliation":[]},{"given":"Susana","family":"Serrazina","sequence":"additional","affiliation":[]},{"given":"Laura","family":"Saavedra","sequence":"additional","affiliation":[]},{"given":"Fernando V.","family":"Dias","sequence":"additional","affiliation":[]},{"given":"Reiaz","family":"Ul-Rehman","sequence":"additional","affiliation":[]}],"member":"1965","published-online":{"date-parts":[[2015,10,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2202","DOI":"10.1105\/tpc.113.110411","article-title":"Rapid structural changes and acidification of guard cell vacuoles during stomatal closure require phosphatidylinositol 3,5-bisphosphate","volume":"25","author":"Bak","year":"2013","journal-title":"Plant Cell"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1104\/pp.108.120212","article-title":"Magnitude and direction of vesicle dynamics in growing pollen tubes using spatiotemporal image correlation spectroscopy and fluorescence recovery after photobleaching","volume":"147","author":"Bove","year":"2008","journal-title":"Plant Physiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1093\/jxb\/erg043","article-title":"Endo-exocytosis in the pollen tube apex is differentially regulated by Ca2+ and GTPases","volume":"54","author":"Camacho","year":"2003","journal-title":"J. Exp. Bot."},{"key":"B4","doi-asserted-by":"publisher","first-page":"152","DOI":"10.4161\/psb.1.3.2999","article-title":"Correlative analysis of apical secretion and [Ca2+]c in pollen tube growth and reorientation","volume":"1","author":"Castanho Coelho","year":"2006","journal-title":"Plant Signal. Behav."},{"key":"B5","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1146\/annurev.arplant.59.032607.092921","article-title":"Structural and signaling networks for the polar cell growth machinery in pollen tubes","volume":"59","author":"Cheung","year":"2008","journal-title":"Annu. Rev. Plant Biol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1042\/BJ20081950","article-title":"Phosphatidylinositol 3,5-bisphosphate and Fab1p\/PIKfyve under PPIn endo-lysosome function","volume":"419","author":"Dove","year":"2009","journal-title":"Biochem. J."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1438","DOI":"10.1105\/tpc.106.041582","article-title":"Petunia phospholipase C1 is involved in pollen tube growth","volume":"18","author":"Dowd","year":"2006","journal-title":"Plant Cell"},{"key":"B8","doi-asserted-by":"publisher","first-page":"14531","DOI":"10.1073\/pnas.0701781104","article-title":"A cyclic nucleotide-gated channel is essential for polarized tip growth of pollen","volume":"104","author":"Frietsch","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B9","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1083\/jcb.143.1.65","article-title":"Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis","volume":"143","author":"Gary","year":"1998","journal-title":"J. Cell Biol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"3538","DOI":"10.1105\/tpc.114.127381","article-title":"Overexpression of the tomato pollen receptor kinase LePRK1 rewires pollen tube growth to a blebbing mode","volume":"26","author":"Gui","year":"2014","journal-title":"Plant Cell"},{"key":"B11","doi-asserted-by":"publisher","first-page":"3083","DOI":"10.1093\/jxb\/ers023","article-title":"The pollen-specific R-SNARE\/longin PiVAMP726 mediates fusion of endo- and exocytic compartments in pollen tube tip growth","volume":"63","author":"Guo","year":"2012","journal-title":"J. Exp. Bot."},{"key":"B12","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1016\/j.bbalip.2014.09.018","article-title":"Plant phosphoinositides-complex networks controlling growth and adaptation","volume":"1851","author":"Heilmann","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"B13","doi-asserted-by":"publisher","first-page":"3519","DOI":"10.1105\/tpc.106.047373","article-title":"Pollen tube tip growth depends on plasma membrane polarization mediated by tobacco PLC3 activity and endocytic membrane recycling","volume":"18","author":"Helling","year":"2006","journal-title":"Plant Cell"},{"key":"B14","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.tplants.2011.10.007","article-title":"Calcium entry into pollen tubes","volume":"17","author":"Hepler","year":"2012","journal-title":"Trends Plant Sci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1104\/pp.110.167981","article-title":"Loss-of-function and gain-of-function mutations in FAB1A\/B impair endomembrane homeostasis, conferring pleiotropic developmental abnormalities in Arabidopsis","volume":"155","author":"Hirano","year":"2011","journal-title":"Plant Physiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"4181","DOI":"10.1021\/bi00436a009","article-title":"Phospholipid asymmetry in large unilamellar vesicles induced by transmembrane pH gradients","volume":"28","author":"Hope","year":"1989","journal-title":"Biochemistry"},{"key":"B17","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1038\/ncb1348","article-title":"V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway","volume":"8","author":"Hurtado-Lorenzo","year":"2006","journal-title":"Nat. Cell Biol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"3312","DOI":"10.1105\/tpc.108.059568","article-title":"Type B phosphatidylinositol-4-phosphate 5-kinases mediate Arabidopsis and Nicotiana tabacum pollen tube growth by regulating apical pectin secretion","volume":"20","author":"Ischebeck","year":"2008","journal-title":"Plant Cell"},{"key":"B19","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1111\/j.1365-313X.2010.04435.x","article-title":"Phosphatidylinositol-4,5-bisphosphate influences Nt-Rac5-mediated cell expansion in pollen tubes of Nicotiana tabacum","volume":"65","author":"Ischebeck","year":"2010","journal-title":"Plant J."},{"key":"B20","doi-asserted-by":"publisher","first-page":"2519","DOI":"10.1091\/mbc.E14-11-1527","article-title":"A quantitative imaging-based screen reveals the exocyst as a network hub connecting endocytosis and exocytosis","volume":"26","author":"Jose","year":"2015","journal-title":"Mol. Biol. Cell"},{"key":"B21","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1083\/jcb.145.2.317","article-title":"Rac homologues and compartmentalized phosphatidylinositol 4, 5-bisphosphate act in a common pathway to regulate polar pollen tube growth","volume":"145","author":"Kost","year":"1999","journal-title":"J. Cell Biol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1105\/tpc.107.056119","article-title":"The Arabidopsis phosphatidylinositol phosphate 5-kinase PIP5K3 is a key regulator of root hair tip growth","volume":"20","author":"Kusano","year":"2008","journal-title":"Plant Cell"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1083\/jcb.200801086","article-title":"Rho-GTPase-dependent filamentous actin dynamics coordinate vesicle targeting and exocytosis during tip growth","volume":"181","author":"Lee","year":"2008","journal-title":"J. Cell Biol."},{"issue":"Suppl. A","key":"B24","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1006\/anbo.1999.0991","article-title":"Signaling pathways in pollen tube growth and reorientation","volume":"85","author":"Malh\u00f3","year":"2000","journal-title":"Ann. Bot."},{"key":"B25","doi-asserted-by":"publisher","first-page":"3026","DOI":"10.1105\/tpc.109.069260","article-title":"Exocytosis precedes and predicts the increase in growth in oscillating pollen tubes","volume":"21","author":"McKenna","year":"2009","journal-title":"Plant Cell"},{"key":"B26","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1126\/science.1201101","article-title":"Glutamate receptor-like genes form Ca2+ channels in pollen tubes and are regulated by pistil D-serine","volume":"332","author":"Michard","year":"2011","journal-title":"Science"},{"key":"B27","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1104\/pp.109.152686","article-title":"A dibasic amino acid pair conserved in the activation loop directs plasma membrane localization and is necessary for activity of plant type I\/II phosphatidylinositol phosphate kinase","volume":"153","author":"Mikami","year":"2010","journal-title":"Plant Physiol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1093\/jxb\/eri163","article-title":"Phosphoinositides and phosphatidic acid regulate pollen tube growth and reorientation through modulation of [Ca2+]c and membrane secretion","volume":"56","author":"Monteiro","year":"2005","journal-title":"J. Exp. Bot."},{"key":"B29","doi-asserted-by":"publisher","first-page":"3804","DOI":"10.1242\/jcs.012138","article-title":"Distinct endocytic pathways identified in tobacco pollen tubes using charged nanogold","volume":"120","author":"Moscatelli","year":"2007","journal-title":"J. Cell Sci."},{"key":"B30","doi-asserted-by":"publisher","first-page":"211","DOI":"10.3390\/plants2020211","article-title":"Endocytic pathways and recycling in growing pollen tubes","volume":"2","author":"Onelli","year":"2013","journal-title":"Plants"},{"key":"B31","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1007\/s00709-005-0103-9","article-title":"Endocytosis and vesicle trafficking during tip growth of root hairs","volume":"226","author":"Ovecka","year":"2005","journal-title":"Protoplasma"},{"key":"B32","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1242\/jcs.49.1.261","article-title":"Determination of secretory vesicle production rates by dictyossomes in pollen tubes of Tradescantia using cytochalasin D","volume":"49","author":"Picton","year":"1981","journal-title":"J. Cell Sci."},{"key":"B33","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1111\/j.1365-313X.2011.04623.x","article-title":"PIPKs are essential for rhizoid elongation and caulonemal cell development in the moss Physcomitrella patens","volume":"67","author":"Saavedra","year":"2011","journal-title":"Plant J."},{"key":"B34","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.4161\/psb.21547","article-title":"PIP kinases and their role in plant tip growing cells","volume":"7","author":"Saavedra","year":"2012","journal-title":"Plant Signal. Behav."},{"key":"B35","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1093\/jxb\/erv052","article-title":"The song of lipids and proteins: dynamic lipid\u2013protein interfaces in the regulation of plant cell polarity at different scales","volume":"66","author":"Sekere\u0161","year":"2015","journal-title":"J. Exp. Bot."},{"key":"B36","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1111\/nph.12836","article-title":"Characterization of FAB1 phosphatidylinositol kinases in Arabidopsis pollen tube growth and fertilization","volume":"203","author":"Serrazina","year":"2014","journal-title":"New Phytol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1186\/1471-2229-10-179","article-title":"Asymmetric localization of Arabidopsis syntaxins at the pollen tube apical and sub-apical zones is involved in tip growth","volume":"10","author":"Silva","year":"2010","journal-title":"BMC Plant Biol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"3050","DOI":"10.1105\/tpc.108.058826","article-title":"Arabidopsis phosphatidylinositol-4-monophosphate 5-kinase 4 regulates pollen tube growth and polarity by modulating membrane recycling","volume":"20","author":"Sousa","year":"2008","journal-title":"Plant Cell"},{"key":"B39","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1016\/j.pbi.2011.08.001","article-title":"The ins and outs of cellular Ca2+ transport","volume":"14","author":"Spalding","year":"2011","journal-title":"Curr. Opin. Plant Biol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1105\/tpc.107.052852","article-title":"The type B phosphatidylinositol-4-phosphate 5-kinase 3 is essential for root hair formation in Arabidopsis thaliana","volume":"20","author":"Stenzel","year":"2008","journal-title":"Plant Cell"},{"key":"B41","doi-asserted-by":"publisher","first-page":"114","DOI":"10.3389\/fpls.2011.00114","article-title":"Variable regions of PI4P 5-kinases direct PtdIns(4,5)P2 towards alternative regulatory functions in tobacco pollen tubes","volume":"2","author":"Stenzel","year":"2012","journal-title":"Front. Plant Sci."},{"key":"B42","doi-asserted-by":"publisher","first-page":"e55277","DOI":"10.1371\/journal.pone.0055277","article-title":"Cyclic nucleotide gated channels 7 and 8 are essential for male reproductive fertility","volume":"8","author":"Tunc-Ozdemir","year":"2013","journal-title":"PLoS ONE"},{"key":"B43","doi-asserted-by":"publisher","first-page":"665","DOI":"10.4161\/psb.6.5.14423","article-title":"Localization of Arabidopsis SYP125 syntaxin in the plasma membrane sub-apical and distal zones of growing pollen tubes","volume":"6","author":"Ul-Rehman","year":"2011","journal-title":"Plant Signal. Behav."},{"key":"B44","doi-asserted-by":"publisher","first-page":"e5744","DOI":"10.1371\/journal.pone.0005744","article-title":"Lifeact-mEGFP reveals a dynamic apical F-Actin network in tip growing plant cells","volume":"4","author":"Vidali","year":"2009","journal-title":"PLoS ONE"},{"key":"B45","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1093\/mp\/ssr011","article-title":"Vacuolar sorting receptor (VSR) proteins reach the plasma membrane in germinating pollen tubes","volume":"4","author":"Wang","year":"2011","journal-title":"Mol. Plant"},{"key":"B46","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.1016\/j.celrep.2013.03.010","article-title":"SNARE proteins synaptobrevin, SNAP-25, and syntaxin are involved in rapid and slow endocytosis at synapses","volume":"3","author":"Xu","year":"2013","journal-title":"Cell Rep."},{"key":"B47","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1016\/j.pbi.2013.10.013","article-title":"Exocyst complexes multiple functions in plant cells secretory pathways","volume":"16","author":"Z\u00e1rsk\u00fd","year":"2013","journal-title":"Curr Opin. Plant Biol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"95","DOI":"10.3389\/fpls.2012.00095","article-title":"Evolutionary and structural perspectives of plant cyclic nucleotide-gated cation channel","volume":"3","author":"Zelman","year":"2012","journal-title":"Front. Plant Sci."},{"key":"B49","doi-asserted-by":"publisher","first-page":"4031","DOI":"10.1105\/tpc.110.076760","article-title":"Phosphoinositides regulate clathrin-dependent endocytosis at the tip of pollen tubes in Arabidopsis and tobacco","volume":"22","author":"Zhao","year":"2010","journal-title":"Plant Cell"},{"key":"B50","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1093\/jxb\/ern007","article-title":"Vesicle trafficking dynamics and visualization of zones of exocytosis and endocytosis in tobacco pollen tubes","volume":"59","author":"Zonia","year":"2008","journal-title":"J. Exp. Bot."}],"container-title":["Frontiers in Plant Science"],"original-title":[],"deposited":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T18:34:58Z","timestamp":1653244498000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/Article\/10.3389\/fpls.2015.00816\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,6]]},"references-count":50,"URL":"https:\/\/doi.org\/10.3389\/fpls.2015.00816","relation":{},"ISSN":["1664-462X"],"issn-type":[{"type":"electronic","value":"1664-462X"}],"subject":[],"published":{"date-parts":[[2015,10,6]]}}}