{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T14:12:15Z","timestamp":1774879935342,"version":"3.50.1"},"reference-count":48,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Psychiatry"],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The quality of the relationship between persons with dementia and family carers influences health and quality-of-life outcomes. Little is known regarding those at higher risk of experiencing a decline in relationship quality, who could potentially benefit the most from interventions. We aimed to identify these risk profiles and explore the underlying factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We applied a latent profile analysis to relationship quality data from a 1-year follow-up of 350 dyads of persons with dementia and their informal carers from the Actifcare cohort in eight European countries. Assessments included sociodemographic, clinical, functional, psychosocial and quality-of-life measures. Relationship quality was assessed with the Positive Affect Index. A discriminant analysis explored factors influencing the risk profiles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were two relationship quality profiles among persons with dementia (gradually decreasing, 74.0%; low but improving, 26%) and two among carers (steadily poor, 57.7%; consistently positive, 42.3%). The \u2018gradually decreasing\u2019 profile (persons with dementia) was related to their levels of dependence and unmet needs, along with carers\u2019 social distress and negative feelings, lower baseline RQ and sense of coherence. The \u2018steadily poor\u2019 profile (carers) was influenced by their social distress and negative feelings, lower sense of coherence and perceived social support. These two predominant profiles showed significant decreases in quality-of-life over one year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Specific profiles of persons with dementia and their carers are at risk of worse relationship quality trajectories. By considering modifiable related factors (e.g., carers\u2019 stress), our findings can help develop tailored, effective interventions.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fpsyt.2024.1394665","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T04:23:06Z","timestamp":1726028586000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Addressing relationship quality of people with dementia and their family carers: which profiles require most support?"],"prefix":"10.3389","volume":"15","author":[{"given":"Maria J.","family":"Marques","sequence":"first","affiliation":[]},{"given":"Bob","family":"Woods","sequence":"additional","affiliation":[]},{"given":"Hannah","family":"Jelley","sequence":"additional","affiliation":[]},{"given":"Liselot","family":"Kerpershoek","sequence":"additional","affiliation":[]},{"given":"Louise","family":"Hopper","sequence":"additional","affiliation":[]},{"given":"Kate","family":"Irving","sequence":"additional","affiliation":[]},{"given":"Anja","family":"Bieber","sequence":"additional","affiliation":[]},{"given":"Astrid","family":"Stephan","sequence":"additional","affiliation":[]},{"given":"Anders","family":"Sk\u00f6ldunger","sequence":"additional","affiliation":[]},{"given":"Britt\u2010Marie","family":"Sj\u00f6lund","sequence":"additional","affiliation":[]},{"given":"Geir","family":"Selbaek","sequence":"additional","affiliation":[]},{"given":"Janne","family":"R\u00f8svik","sequence":"additional","affiliation":[]},{"given":"Orazio","family":"Zanetti","sequence":"additional","affiliation":[]},{"given":"Daniel M.","family":"Portolani","sequence":"additional","affiliation":[]},{"given":"Jo\u00e3o","family":"Mar\u00f4co","sequence":"additional","affiliation":[]},{"given":"Niels","family":"Janssen","sequence":"additional","affiliation":[]},{"given":"Eva Y.L.","family":"Tan","sequence":"additional","affiliation":[]},{"given":"Marjolein","family":"de Vugt","sequence":"additional","affiliation":[]},{"given":"Frans","family":"Verhey","sequence":"additional","affiliation":[]},{"given":"Manuel","family":"Gon\u00e7alves-Pereira","sequence":"additional","affiliation":[]}],"member":"1965","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1037\/amp0000103","article-title":"Advancing social connection as a public health priority in the United States","volume":"72","author":"Holt-Lunstad","year":"2017","journal-title":"Am Psychol"},{"key":"B2","volume-title":"World Alzheimer report 2015: the global impact of dementia - an analysis of prevalence, incidence, cost and trends","author":"Prince","year":"2015"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(21)00249-8\/ATTACHMENT\/60E03FD1-38B2-4B40-A91D-9AFDDA22B45E\/MMC1.PDF","article-title":"Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019","volume":"7","author":"Nichols","year":"2022","journal-title":"Lancet Public Health"},{"key":"B4","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1080\/13607863.2012.678482","article-title":"Caregivers\u2019 relationship closeness with the person with dementia predicts both positive and negative outcomes for carers\u2019 physical health and psychological well-being","volume":"16","author":"Fauth","year":"2012","journal-title":"Aging Ment Health"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1093\/geronb\/gbp052","article-title":"Caregiver-recipient closeness and symptom progression in alzheimer disease. 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