{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:37:45Z","timestamp":1787315865364,"version":"build-2736575974"},"reference-count":21,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T00:00:00Z","timestamp":1734307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Young Minds"],"abstract":"<jats:p>Throughout human history, we have witnessed several major breakthroughs in science and technology that have transformed our society, such as the Industrial Revolution and the Internet Revolution. The next revolution is already underway, made possible by a technology I co-discovered that allows scientists to change the genes of many organisms and plants. This powerful technology, called CRISPR, could improve human health, help crops grow better, and fight climate change. CRISPR could even influence human evolution. In this article, I will explain how CRISPR works, my discovery of a specific CRISPR system called CRISPR-Cas9, and the current and future uses of this technology. Finally, I will discuss some of the ethical concerns around using CRISPR tools and the actions scientists and societies should take to ensure responsible and impactful application of CRISPR technology.<\/jats:p>","DOI":"10.3389\/frym.2024.1063878","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T04:18:09Z","timestamp":1734322689000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["The CRISPR Revolution: Can We Change Genes for the Better?"],"prefix":"10.3389","volume":"12","author":[{"given":"Jennifer A.","family":"Doudna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1038\/nrmicro1793","article-title":"CRISPR\u2014a widespread system that provides acquired resistance against phages in bacteria and archaea","volume":"6","author":"Sorek","year":"2008","journal-title":"Nat. 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