{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T06:09:47Z","timestamp":1772431787271,"version":"3.50.1"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Solid oral tumors represent approximately 6% of malignant neoplasms in dogs, with melanoma, squamous cell carcinoma, and fibrosarcoma identified as the most prevalent types. This case-control study examined internal and external factors associated with their development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Owners of 80 dogs with oral tumors and 95 healthy controls completed a structured epidemiological questionnaire. Univariate and multivariate analyses were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Significant associations were identified regarding age, weight, reproductive status, dietary habits, and environmental exposures, such as barbecue smoke and professional dental cleaning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>These findings suggest potential risk factors, though the study\u2019s observational design requires cautious interpretation. Further investigation through prospective studies is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fvets.2026.1738835","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T05:21:24Z","timestamp":1772428884000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Risk factors associated with solid oral tumors in dogs: a case\u2013control study in S\u00e3o Paulo, Brazil"],"prefix":"10.3389","volume":"13","author":[{"given":"Marcella Collaneri","family":"Carrilho","sequence":"first","affiliation":[{"name":"Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo","place":["S\u00e3o Paulo, Brazil"]}]},{"given":"Katia","family":"Pinello","sequence":"additional","affiliation":[{"name":"Epidemiology Unit (EPIUnit), Institute of Public Health of the University of Porto (ISPUP)","place":["Porto, Portugal"]}]},{"given":"Helena Sofia","family":"Salgueiro","sequence":"additional","affiliation":[{"name":"Epidemiology Unit (EPIUnit), Institute of Public Health of the University of Porto (ISPUP)","place":["Porto, Portugal"]}]},{"given":"Laura","family":"Sichero","sequence":"additional","affiliation":[{"name":"Center for Translational Research in Oncology, Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo-ICESP, Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo FMUSP HC","place":["S\u00e3o Paulo, SP, Brazil"]}]},{"given":"Denner Santos","family":"dos Anjos","sequence":"additional","affiliation":[{"name":"Eletro-Onkovet Service","place":["Franca, SP, Brazil"]}]},{"given":"Guilherme","family":"da Silva Rogerio","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo","place":["S\u00e3o Paulo, Brazil"]}]},{"given":"Andrigo Barbosa","family":"de Nardi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinic and Surgery, Universidade Estadual Paulista (UNESP)","place":["Jaboticabal, Brazil"]}]},{"given":"Maria Lucia Zaidan","family":"Dagli","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental and Comparative Oncology, School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo","place":["S\u00e3o Paulo, Brazil"]}]}],"member":"1965","published-online":{"date-parts":[[2026,3,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5380\/avs.v7i2.3977","article-title":"Preval\u00eancia de neoplasias e modalidades de tratamentos em c\u00e3es, atendidos no hospital veterin\u00e1rio da Universidade Federal do Paran\u00e1","volume":"7","author":"De Nardi","year":"2002","journal-title":"Arch Vet Sci"},{"key":"ref2","volume-title":"Withrow and MacEwen's small animal clinical 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