{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T10:29:59Z","timestamp":1789295399719,"version":"build-2803163510"},"reference-count":25,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2004,9,30]],"date-time":"2004-09-30T00:00:00Z","timestamp":1096502400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Ten new azo Schiff bases 5a-h and 7a-b were prepared in excellent yields via the condensation of different aromatic amines and a new azoaldehyde, 2-hydroxy-3- methoxy-5-(4-methoxyphenylazo)benzaldehyde (4) by two different methods. All new compounds were tested against five microorganisms: Staphylococcus aureus (Gram positive and methicillin resistant), Bacillus subtilis (Gram positive), Kelebsiella pneumonia, Pseudomonas aeruginosa and Escherichia coli (all Gram negative). Compounds 4, 5a, 5c, 5d and 5g were moderately active against Staphylococcus aureus and Bacillus subtilis. Compound 7b was highly active against Bacillus subtilis and moderately active against Staphylococcus aureus. Other compounds were inactive against these strains of bacteria. The antifungal activities of these compounds were also tested against eight different fungal species. None of them were active against the fungi species tested.<\/jats:p>","DOI":"10.3390\/91000815","type":"journal-article","created":{"date-parts":[[2008,10,25]],"date-time":"2008-10-25T13:32:11Z","timestamp":1224941531000},"page":"815-824","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":139,"title":["Synthesis of Novel Azo Schiff Bases and Their Antibacterial and Antifungal Activities"],"prefix":"10.3390","volume":"9","author":[{"given":"A.  A.","family":"Jarrahpour","sequence":"first","affiliation":[{"name":"Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Motamedifar","sequence":"additional","affiliation":[{"name":"Department of Bacteriology and Virology, Shiraz Medical School, Shiraz University Medical Science, Shiraz 71345, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Pakshir","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Mycology, Shiraz Medical School, Shiraz University Medical Science, Shiraz 71345, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Hadi","sequence":"additional","affiliation":[{"name":"Department of Bacteriology and Virology, Shiraz Medical School, Shiraz University Medical Science, Shiraz 71345, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Zarei","sequence":"additional","affiliation":[{"name":"Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2004,9,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Venturini, A., and Gonzalez, J.J. (2002). J. Org. Chem., 67, 9089\u20139092.","DOI":"10.1021\/jo026188h"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Taggi, A.E., Hafez, A.M., Wack, H., Young, B., Ferraris, D., and Lectka, T.J. (2002). J. Am. Chem. Soc., 124, 6626\u20136635.","DOI":"10.1021\/ja0258226"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Delpiccolo, C.M.L., and Mata, E.G. (2002). Tetrahedron: Asymmetry, 13, 905\u2013910.","DOI":"10.1016\/S0957-4166(02)00214-8"},{"key":"ref_4","first-page":"474","article-title":"Indian Chem","volume":"78","author":"More","year":"2001","journal-title":"J. Indian Chem. Soc."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Pandeya, S.N., Sriram, D., Nath, G., and De Clercq, E. (1999). Il Farmaco, 54, 624\u2013628.","DOI":"10.1016\/S0014-827X(99)00075-0"},{"key":"ref_6","unstructured":"Baseer, M.A., Jadhav, V.D., Phule, R.M., Archana, Y.V., and Vibhute, Y.B. (2000). Orient. J. Chem., 16, 553\u2013556."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"El-Masry, A.H., Fahmy, H.H., and Abdelwahed, S.H.A. (2000). Molecules, 5, 1429\u20131438.","DOI":"10.3390\/51201429"},{"key":"ref_8","unstructured":"Karia, F.D., and Parsania, P.H. (1999). Asian J. Chem., 11, 991\u2013995."},{"key":"ref_9","unstructured":"Kabeer, A.S., Baseer, M.A., and Mote, N.A. (2001). Asian J. Chem., 13, 496\u2013500."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Singh, W.M., and Dash, B.C. (1988). Pesticides, 22, 33\u201337.","DOI":"10.1177\/153857448802200104"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Wang, P-H., Keck, J.G., Lien, E.J., and Lai, M.M.C.J. (1990). J. Med. Chem., 33, 608\u2013614.","DOI":"10.1021\/jm00164a023"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Das, A., Trousdale, M.D., Ren, S., and Lien, E.J. (1999). Antiviral Res, 44, 201\u2013208.","DOI":"10.1016\/S0166-3542(99)00070-4"},{"key":"ref_13","unstructured":"Desai, S.B., Desai, P.B., and Desai, K.R. (2001). Hetrocycl. Commun., 7, 83\u201390."},{"key":"ref_14","unstructured":"Pathak, P., Jolly, V.S., and Sharma, K.P. (2000). Orient. J. Chem., 16, 161\u2013162."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Kuz\u2019min, V.E., Lozitsky, V.P., Kamalov, G.L., Lozitskaya, R.N., Zheltvay, A.I., Fedtchouk, A.S., and Kryzhanovsky, D.N. (2000). Acta Biochim. Polon., 47, 867\u2013876.","DOI":"10.18388\/abp.2000_4005"},{"key":"ref_16","unstructured":"Phatak, P., Jolly, V.S., and Sharma, K.P. (2000). Orient. J. Chem., 16, 493\u2013494."},{"key":"ref_17","unstructured":"Das, B.P., Choudhury, R.T., Das, K.G., Choudhury, D.N., and Choudhury, B. (1994). Chem. Environ. Res., 3, 19\u201323."},{"key":"ref_18","unstructured":"Samadhiya, S., and Halve, A. (2001). Orient. J. Chem., 17, 119\u2013122."},{"key":"ref_19","unstructured":"Jolly, V.S., Pathak, P., and Jain, R. (1993). J. Indian Chem. Soc., 70, 505\u2013507."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Halve, A., and Goyal, A. (1996). Orient. J. Chem., 12, 87\u201388.","DOI":"10.1159\/000189926"},{"key":"ref_21","unstructured":"Furniss, B.S., Hannaferd, A.J., Rogers, V., Smith, P.W.G., and Tatchell, A.R. (1981). Vogel\u2019sTextbook of Practical Organic Chemistry, Longman, Inc.. [4th ed.]."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Jarrahpour, A.A., Esmaeilbeig, A.R., and Zarei, M. (2004). Molbank, M371.","DOI":"10.3390\/M371"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Matsui, S., Hashimoto, Y., and Saigo, K. (1998). Synthesis, 1161\u20131166.","DOI":"10.1055\/s-1998-2117"},{"key":"ref_24","unstructured":"Forbes, B.A., Sham, D.F., and Weissfeld, A.S. (2002). Bailey and Scott\u2018s Diagnostic Microbiology, Mosby, Inc.. [11th ed.]."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Rex, J.H., Pfaller, M.I., Walsh, T.J., Chaturvdei, V., Espinel-Ingroff, A., Ghannoum, M.A., Gosey, L.L., Odds, F.C., Rinaldi, M.G., Sheehan, D.G., and Warnock, D.W. (2001). Clin. Microbiol. Rev., 14, 643\u2013658.","DOI":"10.1128\/CMR.14.4.643-658.2001"}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/9\/10\/815\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T22:26:07Z","timestamp":1760221567000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/9\/10\/815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9,30]]},"references-count":25,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2004,10]]}},"alternative-id":["91000815"],"URL":"https:\/\/doi.org\/10.3390\/91000815","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,9,30]]}}}