{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T10:55:55Z","timestamp":1774263355865,"version":"3.50.1"},"reference-count":49,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T00:00:00Z","timestamp":1774137600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Algorithms"],"abstract":"<jats:p>The analysis of brain data through electroencephalography (EEG) has become essential in neuroscience, affective computing, and brain\u2013computer interfaces. Recent work associates EEG features with artificial neurotransmitter models, simulating emotions and rational\u2013emotional decision-making using complexity theory. However, current methods face limitations: (1) linear temporal representations lacking memory and anticipation, (2) limited contextual adaptation, (3) difficulty with paradoxical affective states, and (4) absence of ethical reasoning in decision-making. We present a framework based on Sophimatics, using complex time (t=treal+i\u22c5timag\u2208C) where treal represents chronology and timag encodes experiential dimensions including memory depth and anticipatory imagination. The Super Time Cognitive Neural Network (STCNN) architecture enables the parallel processing of objective time sequences and subjective cognitive experiences. Our Sophimatics-assisted EEG analysis achieves: (1) two-dimensional temporal coherence integrating past experiences and future projections, (2) context-sensitive adaptation via ontological knowledge graphs, (3) interpretable symbolic reasoning compatible with clinical psychology, (4) mechanisms for resolving affective paradoxes, and (5) ethical constraints ensuring value-based decision-making. Across three case studies (emotion recognition, meditation-induced transitions, and brain\u2013computer interface decision support), integrated Sophimatics models outperform traditional machine learning (15\u201322% accuracy improvement) and complexity theory models (8\u201314% improvement), while offering greater cognitive richness and immunity to incomplete data. Results establish a post-generative AI framework with computational wisdom: relationally interactive, ethically informed, and temporally consistent with human cognitive and affective life. The framework outlines paths toward next-generation neuromorphic systems achieving genuine understanding beyond pattern recognition.<\/jats:p>","DOI":"10.3390\/a19030237","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T09:48:42Z","timestamp":1774259322000},"page":"237","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["From Complexity Theory to Computational Wisdom: Enhancing EEG\u2013Neurotransmitter Models Through Sophimatics for Brain Data Analysis"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3119-4608","authenticated-orcid":false,"given":"Gerardo","family":"Iovane","sequence":"first","affiliation":[{"name":"Department of Computer Science, University of Salerno, 84084 Fisciano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Iovane","sequence":"additional","affiliation":[{"name":"Liceo Scientifico Statale Francesco Severi, 84100 Salerno, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,22]]},"reference":[{"key":"ref_1","unstructured":"Niedermeyer, E., and da Silva, F.L. 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