{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T14:16:26Z","timestamp":1781532986392,"version":"3.54.5"},"reference-count":46,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T00:00:00Z","timestamp":1775952000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003482","name":"Hebei Provincial Department of Education","doi-asserted-by":"publisher","award":["ZD2022102"],"award-info":[{"award-number":["ZD2022102"]}],"id":[{"id":"10.13039\/501100003482","id-type":"DOI","asserted-by":"publisher"}]},{"award":["ZD2022102"],"award-info":[{"award-number":["ZD2022102"]}],"id":[{"id":"https:\/\/ror.org\/01jkyjd96","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Algorithms"],"abstract":"<jats:p>Medical images commonly exhibit low contrast, weak boundaries, and complex textures. In addition, significant semantic differences exist between deep-level semantic features and shallow-level detail features, posing challenges for multi-scale feature fusion in terms of detail preservation and structural consistency. To address these issues, a frequency-enhanced and bidirectional feature-guided segmentation network (FBNet) is proposed. The network comprises two core components. The frequency-based enhancement (FBE) module employs the Fast Fourier Transform and applies adaptive modulation to the amplitude spectrum through a content-aware gating mechanism, enhancing detail expression and inter-structural contrast. The Bidirectional Guided Feature Fusion module (BGF) enables bidirectional interaction between shallow and deep features. Additionally, the Structure and Edge Awareness (SEA) module is constructed using directional and variance attention mechanisms to achieve collaborative optimization of structural modeling and edge perception. Experiments on four medical image segmentation datasets show that, compared to the second-best method, FBNet achieves improvements of 2.12, 1.57, 1.37, and 1.56 percentage points on the mIoU metric and 1.54, 1.11, 0.84, and 1.03 percentage points on the mDice metric.<\/jats:p>","DOI":"10.3390\/a19040303","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T08:49:02Z","timestamp":1776070142000},"page":"303","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Research on Medical Image Segmentation Based on Frequency-Domain Enhancement and Edge Awareness"],"prefix":"10.3390","volume":"19","author":[{"given":"Jiamin","family":"Li","sequence":"first","affiliation":[{"name":"College of Artificial Intelligence, North China University of Science and Technology, Tangshan 063210, China"},{"name":"The Hebei Key Laboratory of Industrial Intelligent Perception, Tangshan 063210, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazhi","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Artificial Intelligence, North China University of Science and Technology, Tangshan 063210, China"},{"name":"The Hebei Key Laboratory of Industrial Intelligent Perception, Tangshan 063210, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6508-2308","authenticated-orcid":false,"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"College of Artificial Intelligence, North China University of Science and Technology, Tangshan 063210, China"},{"name":"The Hebei Key Laboratory of Industrial Intelligent Perception, Tangshan 063210, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1109\/TMI.2020.3035253","article-title":"CA-Net: Comprehensive attention convolutional neural networks for explainable medical image segmentation","volume":"40","author":"Gu","year":"2020","journal-title":"IEEE Trans. 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