{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T14:20:47Z","timestamp":1766067647218,"version":"build-2065373602"},"reference-count":60,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T00:00:00Z","timestamp":1671408000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BDCC"],"abstract":"<jats:p>Patients, hospitals, sensors, researchers, providers, phones, and healthcare organisations are producing enormous amounts of data in both the healthcare and drug detection sectors. The real challenge in these sectors is to find, investigate, manage, and collect information from patients in order to make their lives easier and healthier, not only in terms of formulating new therapies and understanding diseases, but also to predict the results at earlier stages and make effective decisions. The volumes of data available in the fields of pharmacology, toxicology, and pharmaceutics are constantly increasing. These increases are driven by advances in technology, which allow for the analysis of ever-larger data sets. Big Data (BD) has the potential to transform drug development and safety testing by providing new insights into the effects of drugs on human health. However, harnessing this potential involves several challenges, including the need for specialised skills and infrastructure. In this survey, we explore how BD approaches are currently being used in the pharmacology, toxicology, and pharmaceutics fields; in particular, we highlight how researchers have applied BD in pharmacology, toxicology, and pharmaceutics to address various challenges and establish solutions. A comparative analysis helps to trace the implementation of big data in the fields of pharmacology, toxicology, and pharmaceutics. Certain relevant limitations and directions for future research are emphasised. The pharmacology, toxicology, and pharmaceutics fields are still at an early stage of BD adoption, and there are many research challenges to be overcome, in order to effectively employ BD to address specific issues.<\/jats:p>","DOI":"10.3390\/bdcc6040161","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T06:58:29Z","timestamp":1671433109000},"page":"161","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["A Survey on Big Data in Pharmacology, Toxicology and Pharmaceutics"],"prefix":"10.3390","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2724-0744","authenticated-orcid":false,"given":"Krithika","family":"Latha Bhaskaran","sequence":"first","affiliation":[{"name":"School of Information Technology and Engineering, Vellore Institute of Technology, Vellore 632014, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8826-2405","authenticated-orcid":false,"given":"Richard Sakyi","family":"Osei","sequence":"additional","affiliation":[{"name":"Information and Communication Technology Department, Faculty of Applied Science and Technology, Dr. Hilla Limann Technical University, Wa P.O. Box 553, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evans","family":"Kotei","sequence":"additional","affiliation":[{"name":"Computer Science Department, Faculty of Applied Science, Kumasi Campus, Kumasi Technical University, Kumasi 00233, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric Yaw","family":"Agbezuge","sequence":"additional","affiliation":[{"name":"Computer Science Department, Faculty of Applied Science, Kumasi Campus, Kumasi Technical University, Kumasi 00233, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4122-6164","authenticated-orcid":false,"given":"Carlos","family":"Ankora","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Faculty of Applied Sciences and Technology, Ho Technical University, Ho P.O. Box HP 217, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2161-7435","authenticated-orcid":false,"given":"Ernest D.","family":"Ganaa","sequence":"additional","affiliation":[{"name":"Information and Communication Technology Department, Faculty of Applied Science and Technology, Dr. Hilla Limann Technical University, Wa P.O. Box 553, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/S0165-6147(97)01051-1","article-title":"What is pharmacology? A discussion","volume":"18","author":"Laurence","year":"1997","journal-title":"Trends Pharmacol. Sci."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1053\/bean.2003.0270","article-title":"What is toxicology and how does toxicity occur?","volume":"17","year":"2003","journal-title":"Best Pract. Res. 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