{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T07:41:48Z","timestamp":1775202108656,"version":"3.50.1"},"reference-count":41,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T00:00:00Z","timestamp":1673308800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Southern Federal University","award":["Priority 2030"],"award-info":[{"award-number":["Priority 2030"]}]},{"name":"Southern Federal University","award":["075-15-2021-1363"],"award-info":[{"award-number":["075-15-2021-1363"]}]},{"name":"Ministry of Science and Higher Education of the Russian Federation","award":["Priority 2030"],"award-info":[{"award-number":["Priority 2030"]}]},{"name":"Ministry of Science and Higher Education of the Russian Federation","award":["075-15-2021-1363"],"award-info":[{"award-number":["075-15-2021-1363"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BDCC"],"abstract":"<jats:p>Microfluidic devices have opened new opportunities for functional material chemical synthesis in a few applications. The screening of microfluidic synthesis processes is an urgent task of the experimental process in terms of automation and intellectualization. This study proposes a methodology and software for extracting the morphological and dynamic characteristics of generated monodisperse droplets from video data streams obtained from a digital microscope. For this purpose, the paper considers an approach to generating an extended feature space characterizing the process of droplet generation using a microfluidic device based on the creation of synthetic image datasets. YOLOv7 was used as an algorithm for detecting objects in the images. When training this algorithm, the values in the test dataset mAP@0.5 0.996 were obtained. The algorithms proposed for image processing and analysis implement the basic functionality to extract the morphological and dynamic characteristics of monodisperse droplets in the synthesis process. Laboratory validation and verification of the software demonstrated high results of the identification of key characteristics of the monodisperse droplets generated by the microfluidic device with the average deviation from the real values not exceeding 8%.<\/jats:p>","DOI":"10.3390\/bdcc7010007","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T04:45:58Z","timestamp":1673412358000},"page":"7","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Online Microfluidic Droplets Characterization Using Microscope Data Intelligent Analysis"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1260-8676","authenticated-orcid":false,"given":"Oleg O.","family":"Kartashov","sequence":"first","affiliation":[{"name":"The Smart Materials Research Institute, Southern Federal University, 178\/24 Sladkova, 344090 Rostov-on-Don, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8172-8666","authenticated-orcid":false,"given":"Sergey V.","family":"Chapek","sequence":"additional","affiliation":[{"name":"The Smart Materials Research Institute, Southern Federal University, 178\/24 Sladkova, 344090 Rostov-on-Don, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7925-6302","authenticated-orcid":false,"given":"Dmitry S.","family":"Polyanichenko","sequence":"additional","affiliation":[{"name":"The Smart Materials Research Institute, Southern Federal University, 178\/24 Sladkova, 344090 Rostov-on-Don, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grigory I.","family":"Belyavsky","sequence":"additional","affiliation":[{"name":"The Smart Materials Research Institute, Southern Federal University, 178\/24 Sladkova, 344090 Rostov-on-Don, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7918-453X","authenticated-orcid":false,"given":"Alexander A.","family":"Alexandrov","sequence":"additional","affiliation":[{"name":"The Smart Materials Research Institute, Southern Federal University, 178\/24 Sladkova, 344090 Rostov-on-Don, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6167-7942","authenticated-orcid":false,"given":"Maria A.","family":"Butakova","sequence":"additional","affiliation":[{"name":"The Smart Materials Research Institute, Southern Federal University, 178\/24 Sladkova, 344090 Rostov-on-Don, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander V.","family":"Soldatov","sequence":"additional","affiliation":[{"name":"The Smart Materials Research Institute, Southern Federal University, 178\/24 Sladkova, 344090 Rostov-on-Don, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"27560","DOI":"10.1039\/D0RA04566G","article-title":"Droplet microfluidics: Fundamentals and its advanced applications","volume":"10","author":"Sohrabi","year":"2020","journal-title":"RSC Adv."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"032004","DOI":"10.1088\/2632-959X\/abcca6","article-title":"Microfluidic devices for synthesizing nanomaterials\u2014A review","volume":"1","author":"Kulkarni","year":"2020","journal-title":"Nano Express"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"041301","DOI":"10.1063\/5.0100206","article-title":"Microfluidic synthesis as a new route to produce novel functional materials","volume":"16","author":"Xie","year":"2022","journal-title":"Biomicrofluidics"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e1600567","DOI":"10.1126\/sciadv.1600567","article-title":"Combinatorial microfluidic droplet engineering for biomimetic material synthesis","volume":"2","author":"Bawazer","year":"2016","journal-title":"Sci. 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