{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T17:37:41Z","timestamp":1774633061718,"version":"3.50.1"},"reference-count":32,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T00:00:00Z","timestamp":1691971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computation"],"abstract":"<jats:p>The construction of a mathematical model of a complicated system is often associated with the evaluation of inputs\u2019 (arguments, factors) influence on the output (response), the identification of important relationships between the variables used, and reduction of the model by decreasing the number of its inputs. These tasks are related to the problems of Sensitivity Analysis of mathematical models. The author proposes an alternative approach based on applying Analysis of Finite Fluctuations that uses the Lagrange mean value theorem to estimate the contribution of changes to the variables of a function to the output change. The article investigates the presented approach on an example of a class of fully connected neural network models. As a result of Sensitivity Analysis, a set of sensitivity measures for each input is obtained. For their averaging, it is proposed to use a point-and-interval estimation algorithm using Tukey\u2019s weighted average. The comparison of the described method with the computation of Sobol\u2019s indices is given; the consistency of the proposed method is shown. The computational robustness of the procedure for finding sensitivity measures of inputs is investigated. Numerical experiments are carried out on the neuraldat data set of the NeuralNetTools library of the R data processing language and on data of the healthcare services provided in the Lipetsk region.<\/jats:p>","DOI":"10.3390\/computation11080159","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T10:20:14Z","timestamp":1692008414000},"page":"159","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Sensitivity Analysis of Mathematical Models"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0866-1124","authenticated-orcid":false,"given":"Anton","family":"Sysoev","sequence":"first","affiliation":[{"name":"Department of Applied Mathematics, Lipetsk State Technical University, Moskovskaya Str., 30, RU-398055 Lipetsk, Russia"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Saltelli, A., Ratto, M., Andres, T., Campolongo, F., Cariboni, J., Gatelli, D., Saisana, M., and Tarantola, S. 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