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Tables are an attractive knowledge source in various applications, including knowledge graph engineering. However, a lack of understanding of the semantic structure and meaning of their content may reduce the effectiveness of this process. Hence, the restoration of tabular semantics and the development of knowledge graphs based on semantically annotated tabular data are highly relevant tasks that have attracted a lot of attention in recent years. We propose a hybrid approach using heuristics and machine learning methods for the semantic annotation of relational tabular data and knowledge graph populations with specific entities extracted from the annotated tables. This paper discusses the main stages of the approach, its implementation, and performance testing. We also consider three case studies for the development of domain-specific knowledge graphs in the fields of industrial safety inspection, labor market analysis, and university activities. The evaluation results revealed that the application of our approach can be considered the initial stage for the rapid filling of domain-specific knowledge graphs based on tabular data.<\/jats:p>","DOI":"10.3390\/computation11090175","type":"journal-article","created":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T09:59:31Z","timestamp":1693907971000},"page":"175","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Knowledge Graph Engineering Based on Semantic Annotation of Tables"],"prefix":"10.3390","volume":"11","author":[{"given":"Nikita","family":"Dorodnykh","sequence":"first","affiliation":[{"name":"Matrosov Institute for System Dynamics and Control Theory, Siberian Branch of Russian Academy of Sciences (ISDCT SB RAS), Irkutsk 664033, Russia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9089-5730","authenticated-orcid":false,"given":"Aleksandr","family":"Yurin","sequence":"additional","affiliation":[{"name":"Matrosov Institute for System Dynamics and Control Theory, Siberian Branch of Russian Academy of Sciences (ISDCT SB RAS), Irkutsk 664033, Russia"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1145\/3447772","article-title":"Knowledge Graphs","volume":"54","author":"Hogan","year":"2021","journal-title":"ACM Comput. 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