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The fourth-order compact difference scheme is adopted for approximations of derivatives and interpolations in the incompressible Navier\u2013Stokes equations. The pressure Poisson equation is efficiently solved by the fast Fourier transform (FFT). The framework of approximate factorization significantly simplifies the implementation of the semi-implicit time advancing with a high-order compact scheme. Benchmark tests demonstrate the high accuracy of the proposed numerical method. Secondly, by applying the proposed numerical method, we compute turbulent channel flows at low and moderate Reynolds numbers by direct numerical simulation (DNS) and large eddy simulation (LES). It is found that the predictions of turbulence statistics and especially energy spectra can be obviously improved by adopting the high-order scheme rather than the traditional second-order central difference scheme.<\/jats:p>","DOI":"10.3390\/computation6020031","type":"journal-article","created":{"date-parts":[[2018,4,11]],"date-time":"2018-04-11T12:16:50Z","timestamp":1523449010000},"page":"31","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Application of High-Order Compact Difference Scheme in the Computation of Incompressible Wall-Bounded Turbulent Flows"],"prefix":"10.3390","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2505-5433","authenticated-orcid":false,"given":"Ruifeng","family":"Hu","sequence":"first","affiliation":[{"name":"Research Center for Applied Mechanics, School of Mechano-Electronic Engineering, Xidian University, Xi\u2019an 710071, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Limin","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Mechanics on Disaster and Environment in Western China (Lanzhou University), Ministry of Education, Lanzhou 730000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Mechanics on Disaster and Environment in Western China (Lanzhou University), Ministry of Education, Lanzhou 730000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Mechanics on Disaster and Environment in Western China (Lanzhou University), Ministry of Education, Lanzhou 730000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojing","family":"Zheng","sequence":"additional","affiliation":[{"name":"Research Center for Applied Mechanics, School of Mechano-Electronic Engineering, Xidian University, Xi\u2019an 710071, China"},{"name":"Key Laboratory of Mechanics on Disaster and Environment in Western China (Lanzhou University), Ministry of Education, Lanzhou 730000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,4,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1146\/annurev.fl.28.010196.000401","article-title":"New trends in large-eddy simulations of turbulence","volume":"28","author":"Lesieur","year":"1996","journal-title":"Annu. 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