{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T13:57:49Z","timestamp":1784296669012,"version":"3.55.0"},"reference-count":34,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Suranaree University of Technology (SUT)","award":["195622"],"award-info":[{"award-number":["195622"]}]},{"name":"Thailand Science Research and Innovation (TSRI)","award":["195622"],"award-info":[{"award-number":["195622"]}]},{"name":"National Science, Research and Innovation Fund (NSRF)","award":["195622"],"award-info":[{"award-number":["195622"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computers"],"abstract":"<jats:p>The growing challenges in healthcare services, such as hospital congestion and a persistent shortage of medical personnel, significantly impede effective service delivery. This particularly presents significant challenges for the continuous monitoring of patients with chronic diseases. In comparison, Internet of Things (IoT) based telemonitoring systems offer a promising solution to alleviate these challenges. However, transmitting sensitive and confidential patient health data requires a strong focus on end-to-end security. This includes securing sensitive data within the patient\u2019s home network, during internet transmission, at the endpoint system, and managing sensitive data. In this study, we propose a secure and scalable architecture for a remote health monitoring system that integrates telemedicine technology with the IoT. The proposed solution included a portable remote health monitoring device, an IoT Gateway appliance (IoT GW) in the patient\u2019s home, and an IoT Application Gateway Endpoint (App GW Endpoint) on a cloud infrastructure. A secure communication channel was established by implementing a multi-layered security protocol stack that uses HTTPS over Quick UDP Internet Connection (QUIC), with a focus on optimal security and compatibility, prioritizing cipher suites for data confidentiality and device authentication. The cloud architecture is designed based on the Well-Architected Framework principles to ensure security, high availability, and scalability. Our study shows that storing patient health information is reliable and efficient. Furthermore, the results for processing and transmission times clearly demonstrate that the additional encryption mechanisms have a negligible effect on data transmission latency, while significantly improving security.<\/jats:p>","DOI":"10.3390\/computers14090357","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T12:25:57Z","timestamp":1756470357000},"page":"357","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Integration of Cloud-Based Central Telemedicine System and IoT Device Networks"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3808-0029","authenticated-orcid":false,"given":"Parin","family":"Sornlertlamvanich","sequence":"first","affiliation":[{"name":"School of Computer Engineering, Institute of Engineering, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chatdanai","family":"Phakaket","sequence":"additional","affiliation":[{"name":"SoftwareOne Co., Ltd., Bangkok 10330, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panya","family":"Hantula","sequence":"additional","affiliation":[{"name":"Department of Computer Engineering, Faculty of Engineering and Technology, Rajamangala University of Technology Isan, Nakhon Ratchasima 30000, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1862-0588","authenticated-orcid":false,"given":"Sarunya","family":"Kanjanawattana","sequence":"additional","affiliation":[{"name":"School of Computer Engineering, Institute of Engineering, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuntawut","family":"Kaoungku","sequence":"additional","affiliation":[{"name":"School of Computer Engineering, Institute of Engineering, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2620-930X","authenticated-orcid":false,"given":"Komsan","family":"Srivisut","sequence":"additional","affiliation":[{"name":"School of Computer Engineering, Institute of Engineering, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Takabayashi, K., Tanaka, H., and Sakakibara, K. 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