{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T15:31:41Z","timestamp":1781710301818,"version":"3.54.5"},"reference-count":30,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2016,10,31]],"date-time":"2016-10-31T00:00:00Z","timestamp":1477872000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computers"],"abstract":"<jats:p>This paper surveys the available system architectures for cyber-physical systems. Several candidate architectures are examined using a series of essential qualities for cyber-physical systems for healthcare. Next, diagrams detailing the expected functionality of infusion pumps in two of the architectures are analyzed. The STRIDE Threat Model is then used to decompose each to determine possible security issues and how they can be addressed. Finally, a comparison of the major security issues in each architecture is presented to help determine which is most adaptable to meet the security needs of cyber-physical systems in healthcare.<\/jats:p>","DOI":"10.3390\/computers5040027","type":"journal-article","created":{"date-parts":[[2016,10,31]],"date-time":"2016-10-31T11:09:46Z","timestamp":1477912186000},"page":"27","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["A Security Analysis of Cyber-Physical Systems Architecture for Healthcare"],"prefix":"10.3390","volume":"5","author":[{"given":"Darren","family":"Seifert","sequence":"first","affiliation":[{"name":"Department of Computer Science, University of North Dakota, Grand Forks, ND 58201, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7593-9624","authenticated-orcid":false,"given":"Hassan","family":"Reza","sequence":"additional","affiliation":[{"name":"Department of Computer Science, University of North Dakota, Grand Forks, ND 58201, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2016,10,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1109\/MDT.2010.142","article-title":"Cyberphysical Systems: Workload Modeling and Design Optimization","volume":"28","author":"Marculescu","year":"2011","journal-title":"IEEE Design Test Comput."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s11761-011-0083-x","article-title":"A survey on service-oriented middleware for wireless sensor networks","volume":"5","author":"Mohamed","year":"2011","journal-title":"Serv. 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