{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T16:51:31Z","timestamp":1779295891712,"version":"3.51.4"},"reference-count":14,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T00:00:00Z","timestamp":1560124800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["project FKZ 031A147, GO-Bio"],"award-info":[{"award-number":["project FKZ 031A147, GO-Bio"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB 1002 Project C3"],"award-info":[{"award-number":["SFB 1002 Project C3"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB 937 Project A18"],"award-info":[{"award-number":["SFB 937 Project A18"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010447","name":"Deutsches Zentrum f\u00fcr Herz-Kreislaufforschung","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/100010447","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Data"],"abstract":"<jats:p>We present CaosDB, a Research Data Management System (RDMS) designed to ensure seamless integration of inhomogeneous data sources and repositories of legacy data in a FAIR way. Its primary purpose is the management of data from biomedical sciences, both from simulations and experiments during the complete research data lifecycle. An RDMS for this domain faces particular challenges: research data arise in huge amounts, from a wide variety of sources, and traverse a highly branched path of further processing. To be accepted by its users, an RDMS must be built around workflows of the scientists and practices and thus support changes in workflow and data structure. Nevertheless, it should encourage and support the development and observation of standards and furthermore facilitate the automation of data acquisition and processing with specialized software. The storage data model of an RDMS must reflect these complexities with appropriate semantics and ontologies while offering simple methods for finding, retrieving, and understanding relevant data. We show how CaosDB responds to these challenges and give an overview of its data model, the CaosDB Server and its easy-to-learn CaosDB Query Language. We briefly discuss the status of the implementation, how we currently use CaosDB, and how we plan to use and extend it.<\/jats:p>","DOI":"10.3390\/data4020083","type":"journal-article","created":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T11:39:47Z","timestamp":1560166787000},"page":"83","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["CaosDB\u2014Research Data Management for Complex, Changing, and Automated Research Workflows"],"prefix":"10.3390","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4022-432X","authenticated-orcid":false,"given":"Timm","family":"Fitschen","sequence":"first","affiliation":[{"name":"Max Planck Institute for Dynamics and Self-Organization, 37077 G\u00f6ttingen, Germany"},{"name":"Institute for the Dynamics of Complex Systems, Georg-August-Universit\u00e4t, 37077 G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4124-9649","authenticated-orcid":false,"given":"Alexander","family":"Schlemmer","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Dynamics and Self-Organization, 37077 G\u00f6ttingen, Germany"},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site G\u00f6ttingen, 37075 G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7846-6375","authenticated-orcid":false,"given":"Daniel","family":"Hornung","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Dynamics and Self-Organization, 37077 G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5549-578X","authenticated-orcid":false,"given":"Henrik","family":"tom W\u00f6rden","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Dynamics and Self-Organization, 37077 G\u00f6ttingen, Germany"},{"name":"Institute for the Dynamics of Complex Systems, Georg-August-Universit\u00e4t, 37077 G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3058-1435","authenticated-orcid":false,"given":"Ulrich","family":"Parlitz","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Dynamics and Self-Organization, 37077 G\u00f6ttingen, Germany"},{"name":"Institute for the Dynamics of Complex Systems, Georg-August-Universit\u00e4t, 37077 G\u00f6ttingen, Germany"},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site G\u00f6ttingen, 37075 G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7214-8125","authenticated-orcid":false,"given":"Stefan","family":"Luther","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Dynamics and Self-Organization, 37077 G\u00f6ttingen, Germany"},{"name":"Institute for the Dynamics of Complex Systems, Georg-August-Universit\u00e4t, 37077 G\u00f6ttingen, Germany"},{"name":"German Center for Cardiovascular Research (DZHK), Partner Site G\u00f6ttingen, 37075 G\u00f6ttingen, Germany"},{"name":"Institute of Pharmacology and Toxicology, University Medical Center G\u00f6ttingen, 37075 G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,6,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Nelson, E.K., Piehler, B., Eckels, J., Rauch, A., Bellew, M., Hussey, P., Ramsay, S., Nathe, C., Lum, K., and Krouse, K. 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