{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:27:35Z","timestamp":1760243255776,"version":"build-2065373602"},"reference-count":35,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2014,4,14]],"date-time":"2014-04-14T00:00:00Z","timestamp":1397433600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Entropy"],"abstract":"<jats:p>Interference, in wireless networks, is a central phenomenon when multiple uncoordinated links share a common communication medium. The study of the interference channel was initiated by Shannon in 1961 and since then this problem has been thoroughly elaborated at the Information theoretic level but its characterization still remains an open issue. When multiple uncoordinated links share a common medium the effect of interference is a crucial limiting factor for network performance. In this work, using cross layer cooperative communication techniques, we study how to compensate interference in the context of wireless biomedical networks, where many links transferring biomedical or other health related data may be formed and suffer from all other interfering transmissions, to allow successful receptions and improve the overall network performance. We define the interference limited communication range to be the critical communication region around a receiver, with a number of surrounding interfering nodes, within which a successful communication link can be formed. Our results indicate that we can achieve more successful transmissions by adapting the transmission rate and power, to the path loss exponent, and the selected mode of the underline communication technique allowing interference mitigation and when possible lower power consumption and increase achievable transmission rates.<\/jats:p>","DOI":"10.3390\/e16042085","type":"journal-article","created":{"date-parts":[[2014,4,14]],"date-time":"2014-04-14T12:54:41Z","timestamp":1397480081000},"page":"2085-2104","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Cross Layer Interference Management in Wireless  Biomedical Networks"],"prefix":"10.3390","volume":"16","author":[{"given":"Emmanouil","family":"Spanakis","sequence":"first","affiliation":[{"name":"Computational Medicine Laboratory (CML), Institute of Computer Science (ICS), Foundation for Research and Technology (FORTH), N. Plastira 100, Vassilika Vouton, GR-700 13, Heraklion, Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vangelis","family":"Sakkalis","sequence":"additional","affiliation":[{"name":"Computational Medicine Laboratory (CML), Institute of Computer Science (ICS), Foundation for Research and Technology (FORTH), N. Plastira 100, Vassilika Vouton, GR-700 13, Heraklion, Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kostas","family":"Marias","sequence":"additional","affiliation":[{"name":"Computational Medicine Laboratory (CML), Institute of Computer Science (ICS), Foundation for Research and Technology (FORTH), N. Plastira 100, Vassilika Vouton, GR-700 13, Heraklion, Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apostolos","family":"Traganitis","sequence":"additional","affiliation":[{"name":"Telecommunications and Networks Laboratory (TNL), Institute of Computer Science (ICS), Foundation for Research and Technology (FORTH), and Computer Science Department (CSD), University of Crete (UOC), GR-700 13, Heraklion, Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2014,4,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1080\/19371910902911206","article-title":"An Evolutionary Examination of Telemedicine: A Health and Computer-Mediated Communication Perspective","volume":"25","author":"Breen","year":"2010","journal-title":"Soc. Work Public Health"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Galarraga, M., Serrano, L., Martinez, I., de Toledo, P., and Reynolds, M. (2007, January 23\u201326). Telemonitoring Systems Interoperability Challenge: An Updated Review of the Applicability of ISO\/IEEE 11073 Standards for Interoperability in Telemonitoring. Lyon, France.","DOI":"10.1109\/IEMBS.2007.4353761"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Abreu, C., and Mendes, P. (2013, January 20\u201323). Wireless sensor networks for biomedical applications. Braga, Portugal.","DOI":"10.1109\/ENBENG.2013.6518413"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Laskovski, A.N. (2011). Biomedical Engineering, Trends in Electronics, Communications and Software, InTech.","DOI":"10.5772\/549"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.3390\/s140101598","article-title":"Ontology-Driven Monitoring of Patient\u2019s Vital Signs Enabling Personalized Medical Detection and Alert","volume":"14","author":"Hristoskova","year":"2014","journal-title":"Sensors"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"11435","DOI":"10.3390\/s120911435","article-title":"Enhancing Health Care Delivery through Ambient Intelligence Applications","volume":"12","author":"Kartakis","year":"2012","journal-title":"Sensors"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"93","DOI":"10.2217\/bmm.10.121","article-title":"Applied strategies towards EEG\/MEG biomarker identification in clinical and cognitive research","volume":"5","author":"Sakkalis","year":"2011","journal-title":"Biomark. Med"},{"key":"ref_8","unstructured":"Pelegris, P., Banitsas, K., Orbach, T., and Marias, K. (September, January 31). A novel method to detect Heart Beat Rate using a mobile phone. Buenos Aires, Argentina."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1089\/tmj.2005.11.63","article-title":"The Current State of Telemonitoring: A Comment on the Literature Telemedicine and e-Health","volume":"11","author":"Meystre","year":"2005","journal-title":"Telemed. e-Health"},{"key":"ref_10","first-page":"49","article-title":"Recent Advances in Wireless Sensor Networks for Health Monitoring","volume":"15","author":"Choi","year":"2010","journal-title":"Int. J. Intell. Control Syst"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1109\/MAP.2013.6735479","article-title":"Propagation Models for Body Area Networks: A Survey and New Outlook","volume":"55","author":"Smith","year":"2010","journal-title":"IEEE Antennas Propag. Mag"},{"key":"ref_12","unstructured":"Javaid, N., Khan, N.A., Shakir, M., Khan, M.A., Bouk, S.H., and Khan, Z.A. (2013). Ubiquitous HealthCare in Wireless Body Area Networks\u2014A Survey. arXiv:1303.2062[cs.NI]."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1109\/TITB.2010.2047507","article-title":"An EMI-Aware Prioritized Wireless Access Scheme for e-Health Applications in Hospital Environments","volume":"14","author":"Phunchongharn","year":"2010","journal-title":"IEEE Trans. Inf. Technol. Biomed"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"11196","DOI":"10.3390\/s130911196","article-title":"Cognitive Radio Wireless Sensor Networks: Applications, Challenges and Research Trends","volume":"13","author":"Joshi","year":"2013","journal-title":"Sensors"},{"key":"ref_15","unstructured":"Chiarugi, F., Trypakis, D., and Spanakis, E.G. (2004, January 1\u20133). Problems and Solutions for Storing and Sharing Data from Medical Devices in eHealth Applications. Berlin, Germany."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.2196\/ijmr.2193","article-title":"Diabetes Management Using Modern Information and Communication Technologies and New Care Models","volume":"1","author":"Spanakis","year":"2012","journal-title":"Interact. J. Med. Res"},{"key":"ref_17","unstructured":"Spanakis, E.G., Lelis, P., Chiarugi, F., Chronaki, C., and Tsiknakis, M. (2005, January 20\u201325). R&D challenges in developing an ambient intelligence eHealth platform. Prague, Czech Republic."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Spat, S., H\u00f6ll, B., Beck, B., Chiarugi, F., Kontogiannis, V., Spanakis, E.G., Manousos, D., and Pieber, T. (2011, January 5\u20137). A Mobile Android-based Application for in-hospital Glucose Management in compliance with the Medical Device Directive for Software. Kos Island, Greece.","DOI":"10.1007\/978-3-642-29734-2_29"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Spanakis, E.G., and Voyiatzis, A.G. (2012, January 21\u201323). DAPHNE: A Disruption-Tolerant Application Proxy for e-Health Network Environments. Paris, France.","DOI":"10.1007\/978-3-642-37893-5_10"},{"key":"ref_20","unstructured":"Traganitis, A.P., Spanakis, E.G., and Orphanoudakis, S.C. M-Health: Emerging Mobile Health Systems, Springer."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1109\/MCOM.2003.1235598","article-title":"Cross-layer design for wireless networks","volume":"41","author":"Shakkottai","year":"2003","journal-title":"IEEE Commun. Mag"},{"key":"ref_22","unstructured":"Charafeddine, M., Sezgin, A., and Paulrajm, A. (2007, January 26\u201328). Rate Region Frontiers for n-user Interference Channel with Interference as Noise. Monticello, IL, USA."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1023\/B:WINE.0000028543.41559.ed","article-title":"Interference in Wireless Multi-Hop Ad-Hoc Networks and Its Effect on Network Capacity","volume":"10","author":"Hekmat","year":"2004","journal-title":"Wirel. Netw"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1109\/SURV.2010.032710.00096","article-title":"Modeling Interference in Wireless Ad Hoc Networks","volume":"12","author":"Cardieri","year":"2010","journal-title":"IEEE Commun. Surv. Tutor"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1109\/TWC.2009.070961","article-title":"Many-to-many communication for mobile ad hoc networks","volume":"8","author":"Sadjadpour","year":"2009","journal-title":"IEEE Trans. Wirel. Commun"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Pappas, N., Kountouris, M., and Ephremides, A. (2013, January 9\u201313). The stability region of the two-user interference channel. Sevilla, Spain.","DOI":"10.1109\/ITW.2013.6691293"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1109\/TIT.2009.2021380","article-title":"Gaussian Interference Networks: Sum Capacity in the Low-Interference Regime and New Outer Bounds on the Capacity Region","volume":"55","author":"Annapureddy","year":"2009","journal-title":"IEEE Trans. Inf. Theory"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1109\/TIT.1975.1055432","article-title":"A case where interference does not reduce capacity (Corresp.)","volume":"21","author":"Carleial","year":"1975","journal-title":"IEEE Trans. Inf. Theory"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1109\/18.825799","article-title":"The capacity of wireless networks","volume":"46","author":"Gupta","year":"2000","journal-title":"IEEE Trans. Inf. Theory"},{"key":"ref_30","unstructured":"Rekha, M., Buehrer, R.M., and Jeffrey, H.R. (2006, January 5). Impact of Exclusion Region and Spreading in Spectrum-sharing Ad hoc Networks. Boston, MA, USA."},{"key":"ref_31","unstructured":"Spanakis, E.G., Traganitis, A.P., and Ephremides, A. (2009, January 10\u201312). Rate Region and Power Considerations in a simple 2 \u00d7 2 Interference Channel. Volos, Greece."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Latr\u00e9, B., Braem, B., Moerman, I., Blondia, C., and Demeester, P. (2011). A survey on wireless body area networks. Wirel. Netw, 17.","DOI":"10.1007\/s11276-010-0252-4"},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Guraliuc, A., Serra, A.A., Nepa, P., Manara, G., Potorti, F., and Barsocchi, P. (2009, January 1\u20135). Body posture\/activity detection: Path loss characterization for 2.4 GHz on-body wireless sensors. Charleston, SC, USA.","DOI":"10.1109\/APS.2009.5171661"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Robert, C.P., and Casella, G. (2004). Monte Carlo Statistical Methods, Springer.","DOI":"10.1007\/978-1-4757-4145-2"},{"key":"ref_35","unstructured":"Rappaport, T.S. (2002). Wireless Communications, Principles and Practice, Prentice Hall PTR."}],"container-title":["Entropy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1099-4300\/16\/4\/2085\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:10:15Z","timestamp":1760217015000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1099-4300\/16\/4\/2085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,14]]},"references-count":35,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,4]]}},"alternative-id":["e16042085"],"URL":"https:\/\/doi.org\/10.3390\/e16042085","relation":{},"ISSN":["1099-4300"],"issn-type":[{"type":"electronic","value":"1099-4300"}],"subject":[],"published":{"date-parts":[[2014,4,14]]}}}