{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:19:29Z","timestamp":1782951569055,"version":"3.54.5"},"reference-count":42,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T00:00:00Z","timestamp":1521763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Entropy"],"abstract":"<jats:p>Nanopores have become a subject of interest in the scientific community due to their potential uses in nanometer-scale laboratory and research applications, including infectious disease diagnostics and DNA sequencing. Additionally, they display behavioral similarity to molecular and cellular scale physiological processes. Recent advances in information theory have made it possible to probe the information dynamics of nonlinear stochastic dynamical systems, such as autonomously fluctuating nanopore systems, which has enhanced our understanding of the physical systems they model. We present the results of local (LER) and specific entropy rate (SER) computations from a simulation study of an autonomously fluctuating nanopore system. We learn that both metrics show increases that correspond to fluctuations in the nanopore current, indicating fundamental changes in information generation surrounding these fluctuations.<\/jats:p>","DOI":"10.3390\/e20040221","type":"journal-article","created":{"date-parts":[[2018,3,26]],"date-time":"2018-03-26T03:43:29Z","timestamp":1522035809000},"page":"221","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Information Dynamics of a Nonlinear Stochastic Nanopore System"],"prefix":"10.3390","volume":"20","author":[{"given":"Claire","family":"Gilpin","sequence":"first","affiliation":[{"name":"Department of Physics and Astronomy, University of California-Irvine, Irvine, CA 92697-4575, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4624-3951","authenticated-orcid":false,"given":"David","family":"Darmon","sequence":"additional","affiliation":[{"name":"Department of Military and Emergency Medicine, Uniformed Services University, Bethesda, MD 20814, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuzanna","family":"Siwy","sequence":"additional","affiliation":[{"name":"Department of Physics and Astronomy, University of California-Irvine, Irvine, CA 92697-4575, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Martens","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of California-Irvine, Irvine, CA 92697-2025, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,3,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"6170","DOI":"10.1021\/acs.jpcc.7b00258","article-title":"Solid-State Ionic Diodes Demonstrated in Conical Nanopores","volume":"121","author":"Plett","year":"2017","journal-title":"J. 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