{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:07:32Z","timestamp":1760242052501,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T00:00:00Z","timestamp":1544659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Science Foundation of China","doi-asserted-by":"publisher","award":["61876101","61472231"],"award-info":[{"award-number":["61876101","61472231"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Entropy"],"abstract":"<jats:p>As a non-invasive diagnostic tool, Magnetic Resonance Imaging (MRI) has been widely used in the field of brain imaging. The classification of MRI brain image conditions poses challenges both technically and clinically, as MRI is primarily used for soft tissue anatomy and can generate large amounts of detailed information about the brain conditions of a subject. To classify benign and malignant MRI brain images, we propose a new method. Discrete wavelet transform (DWT) is used to extract wavelet coefficients from MRI images. Then, Tsallis entropy with DNA genetic algorithm (DNA-GA) optimization parameters (called DNAGA-TE) was used to obtain entropy characteristics from DWT coefficients. At last, DNA-GA optimized support vector machine (called DNAGA-KSVM) with radial basis function (RBF) kernel, is applied as a classifier. In our experimental procedure, we use two kinds of images to validate the availability and effectiveness of the algorithm. One kind of data is the Simulated Brain Database and another kind of image is real MRI images which downloaded from Harvard Medical School website. Experimental results demonstrate that our method (DNAGA-TE+KSVM) obtained better classification accuracy.<\/jats:p>","DOI":"10.3390\/e20120964","type":"journal-article","created":{"date-parts":[[2018,12,14]],"date-time":"2018-12-14T03:58:17Z","timestamp":1544759897000},"page":"964","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Classification of MRI Brain Images Using DNA Genetic Algorithms Optimized Tsallis Entropy and Support Vector Machine"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4899-6316","authenticated-orcid":false,"given":"Wenke","family":"Zang","sequence":"first","affiliation":[{"name":"Business School, Shandong Normal University, Jinan 250014, China"}]},{"given":"Zehua","family":"Wang","sequence":"additional","affiliation":[{"name":"Business School, Shandong Normal University, Jinan 250014, China"}]},{"given":"Dong","family":"Jiang","sequence":"additional","affiliation":[{"name":"Business School, Shandong Normal University, Jinan 250014, China"}]},{"given":"Xiyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Business School, Shandong Normal University, Jinan 250014, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4119-0042","authenticated-orcid":false,"given":"Zhenni","family":"Jiang","sequence":"additional","affiliation":[{"name":"Business School, Shandong Normal University, Jinan 250014, China"}]}],"member":"1968","published-online":{"date-parts":[[2018,12,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.media.2006.12.002","article-title":"A Dirichlet process mixture model for brain MRI tissue classification","volume":"11","year":"2007","journal-title":"Med. 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