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We studied the differences in PE and SC in broadband signals and their decomposition into frequency bands (   \u03b4   ,    \u03b8   ,    \u03b1    and    \u03b2   ), considering two modalities: (i) raw time series obtained from the magnetometers and (ii) a reconstruction into cortical sources or regions of interest (ROIs). We conducted our analyses at three levels: (i) at the group level we compared SC in each frequency band and modality between groups; (ii) at the individual level we compared how the [PE, SC] plane differs in each modality; and (iii) at the local level we explored differences in scalp and cortical space. We recovered classical results that considered only broadband signals and found a nontrivial pattern of alterations in each frequency band, showing that SC does not necessarily decrease in AD or MCI.<\/jats:p>","DOI":"10.3390\/e22010116","type":"journal-article","created":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T04:27:09Z","timestamp":1579494429000},"page":"116","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Permutation Entropy and Statistical Complexity in Mild Cognitive Impairment and Alzheimer\u2019s Disease: An Analysis Based on Frequency Bands"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8016-7836","authenticated-orcid":false,"given":"Ignacio","family":"Echegoyen","sequence":"first","affiliation":[{"name":"Laboratory of Biological Networks, Centre for Biomedical Technology, Universidad Polit\u00e9cnica de Madrid (UPM), 28223 Madrid, Spain"},{"name":"Complex Systems Group, Rey Juan Carlos University, 28933 Madrid, Spain"},{"name":"Grupo Interdisciplinar de Sistemas Complejos (GISC), 28911 Madrid, Spain"}]},{"given":"David","family":"L\u00f3pez-Sanz","sequence":"additional","affiliation":[{"name":"Laboratory of Cognitive and Computational Neuroscience, Centre for Biomedical Technology, Universidad Polit\u00e9cnica de Madrid (UPM), 28223 Madrid, Spain"},{"name":"Department of Experimental Psychology, Complutense University of Madrid, 28223 Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3365-8189","authenticated-orcid":false,"given":"Johann H.","family":"Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Grupo Interdisciplinar de Sistemas Complejos (GISC), 28911 Madrid, Spain"},{"name":"Biomedical Engineering Department, Universidad de los Andes, Bogot\u00e1 111711, Colombia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3195-0071","authenticated-orcid":false,"given":"Fernando","family":"Maest\u00fa","sequence":"additional","affiliation":[{"name":"Laboratory of Cognitive and Computational Neuroscience, Centre for Biomedical Technology, Universidad Polit\u00e9cnica de Madrid (UPM), 28223 Madrid, Spain"},{"name":"Department of Experimental Psychology, Complutense University of Madrid, 28223 Madrid, Spain"},{"name":"Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, 28029 Zaragoza, Spain"}]},{"given":"Javier M.","family":"Buld\u00fa","sequence":"additional","affiliation":[{"name":"Laboratory of Biological Networks, Centre for Biomedical Technology, Universidad Polit\u00e9cnica de Madrid (UPM), 28223 Madrid, Spain"},{"name":"Complex Systems Group, Rey Juan Carlos University, 28933 Madrid, Spain"},{"name":"Grupo Interdisciplinar de Sistemas Complejos (GISC), 28911 Madrid, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2020,1,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Alzheimer\u2019s Association (2016). 2016 Alzheimer\u2019s disease facts and figures. 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