{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:18:21Z","timestamp":1771028301584,"version":"3.50.1"},"reference-count":55,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T00:00:00Z","timestamp":1592352000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["DPI2017-84280-R"],"award-info":[{"award-number":["DPI2017-84280-R"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["RTC-2017-6516-1"],"award-info":[{"award-number":["RTC-2017-6516-1"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["0378_AD_EEGWA_2_P"],"award-info":[{"award-number":["0378_AD_EEGWA_2_P"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["0702_MIGRAINEE_2_E"],"award-info":[{"award-number":["0702_MIGRAINEE_2_E"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005053","name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Bioingenier\u00eda, Biomateriales y Nanomedicina","doi-asserted-by":"publisher","award":["CB19\/01\/00012"],"award-info":[{"award-number":["CB19\/01\/00012"]}],"id":[{"id":"10.13039\/501100005053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Entropy"],"abstract":"<jats:p>The reference standard to diagnose pediatric Obstructive Sleep Apnea (OSA) syndrome is an overnight polysomnographic evaluation. When polysomnography is either unavailable or has limited availability, OSA screening may comprise the automatic analysis of a minimum number of signals. The primary objective of this study was to evaluate the complementarity of airflow (AF) and oximetry (SpO2) signals to automatically detect pediatric OSA. Additionally, a secondary goal was to assess the utility of a multiclass AdaBoost classifier to predict OSA severity in children. We extracted the same features from AF and SpO2 signals from 974 pediatric subjects. We also obtained the 3% Oxygen Desaturation Index (ODI) as a common clinically used variable. Then, feature selection was conducted using the Fast Correlation-Based Filter method and AdaBoost classifiers were evaluated. Models combining ODI 3% and AF features outperformed the diagnostic performance of each signal alone, reaching 0.39 Cohens\u2019s kappa in the four-class classification task. OSA vs. No OSA accuracies reached 81.28%, 82.05% and 90.26% in the apnea\u2013hypopnea index cutoffs 1, 5 and 10 events\/h, respectively. The most relevant information from SpO2 was redundant with ODI 3%, and AF was complementary to them. Thus, the joint analysis of AF and SpO2 enhanced the diagnostic performance of each signal alone using AdaBoost, thereby enabling a potential screening alternative for OSA in children.<\/jats:p>","DOI":"10.3390\/e22060670","type":"journal-article","created":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T13:11:32Z","timestamp":1592399492000},"page":"670","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Assessment of Airflow and Oximetry Signals to Detect Pediatric Sleep Apnea-Hypopnea Syndrome Using AdaBoost"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5540-6778","authenticated-orcid":false,"given":"Jorge","family":"Jim\u00e9nez-Garc\u00eda","sequence":"first","affiliation":[{"name":"Biomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1237-3424","authenticated-orcid":false,"given":"Gonzalo C.","family":"Guti\u00e9rrez-Tobal","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Bioingenier\u00eda, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4037-0351","authenticated-orcid":false,"given":"Mar\u00eda","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Bioingenier\u00eda, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3332-1057","authenticated-orcid":false,"given":"Leila","family":"Kheirandish-Gozal","sequence":"additional","affiliation":[{"name":"Department of Child Health, The University of Missouri School of Medicine, Columbia, MO 65212, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8628-4563","authenticated-orcid":false,"given":"Adri\u00e1n","family":"Mart\u00edn-Montero","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1027-2395","authenticated-orcid":false,"given":"Daniel","family":"\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Bioingenier\u00eda, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain"},{"name":"Sleep-Ventilation Unit, Pneumology Service, R\u00edo Hortega University Hospital, 47012 Valladolid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4554-2167","authenticated-orcid":false,"given":"F\u00e9lix","family":"del Campo","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Bioingenier\u00eda, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain"},{"name":"Sleep-Ventilation Unit, Pneumology Service, R\u00edo Hortega University Hospital, 47012 Valladolid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8195-6036","authenticated-orcid":false,"given":"David","family":"Gozal","sequence":"additional","affiliation":[{"name":"Department of Child Health, The University of Missouri School of Medicine, Columbia, MO 65212, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9915-2570","authenticated-orcid":false,"given":"Roberto","family":"Hornero","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red en Bioingenier\u00eda, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2020,6,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1586\/ers.11.7","article-title":"Obstructive sleep apnea syndrome in children","volume":"5","author":"Tauman","year":"2011","journal-title":"Expert Rev. 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