{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T10:43:32Z","timestamp":1776509012281,"version":"3.51.2"},"reference-count":19,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T00:00:00Z","timestamp":1735171200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad de Buenos Aires","award":["UBACyT 20020130100485BA"],"award-info":[{"award-number":["UBACyT 20020130100485BA"]}]},{"name":"Universidad de Buenos Aires","award":["MINCyT PICT 2145 2016"],"award-info":[{"award-number":["MINCyT PICT 2145 2016"]}]},{"name":"Universidad de Buenos Aires","award":["PIP 2014-2016 112-20130100552CO"],"award-info":[{"award-number":["PIP 2014-2016 112-20130100552CO"]}]},{"name":"Universidad de Buenos Aires","award":["I263"],"award-info":[{"award-number":["I263"]}]},{"name":"Agencia","award":["UBACyT 20020130100485BA"],"award-info":[{"award-number":["UBACyT 20020130100485BA"]}]},{"name":"Agencia","award":["MINCyT PICT 2145 2016"],"award-info":[{"award-number":["MINCyT PICT 2145 2016"]}]},{"name":"Agencia","award":["PIP 2014-2016 112-20130100552CO"],"award-info":[{"award-number":["PIP 2014-2016 112-20130100552CO"]}]},{"name":"Agencia","award":["I263"],"award-info":[{"award-number":["I263"]}]},{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","award":["UBACyT 20020130100485BA"],"award-info":[{"award-number":["UBACyT 20020130100485BA"]}]},{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","award":["MINCyT PICT 2145 2016"],"award-info":[{"award-number":["MINCyT PICT 2145 2016"]}]},{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","award":["PIP 2014-2016 112-20130100552CO"],"award-info":[{"award-number":["PIP 2014-2016 112-20130100552CO"]}]},{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","award":["I263"],"award-info":[{"award-number":["I263"]}]},{"name":"Universidad Nacional de la Plata","award":["UBACyT 20020130100485BA"],"award-info":[{"award-number":["UBACyT 20020130100485BA"]}]},{"name":"Universidad Nacional de la Plata","award":["MINCyT PICT 2145 2016"],"award-info":[{"award-number":["MINCyT PICT 2145 2016"]}]},{"name":"Universidad Nacional de la Plata","award":["PIP 2014-2016 112-20130100552CO"],"award-info":[{"award-number":["PIP 2014-2016 112-20130100552CO"]}]},{"name":"Universidad Nacional de la Plata","award":["I263"],"award-info":[{"award-number":["I263"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Entropy"],"abstract":"<jats:p>Myocardial ischaemia is a decompensation of the oxygen supply and demand ratio, often caused by coronary atherosclerosis. During the initial stage of ischaemia, the electrical activity of the heart is disrupted, increasing the risk of malignant arrhythmias. The aim of this study is to understand the differential behaviour of the ECG during occlusion of both the left anterior descending (LAD) and right anterior coronary artery (RCA), respectively, using spatio-temporal quantifiers from information theory. A standard 12-lead ECG was recorded for each patient in the database. The control condition was obtained initially. Then, a percutaneous transluminal coronary angioplasty procedure (PTCA), which encompassed the occlusion\/reperfusion period, was performed. To evaluate information quantifiers, the Bandt and Pompe permutation method was used to estimate the probability distribution associated with the electrocardiographic vector modulus. Subsequently, we analysed the positioning in the H\u00d7C causal plane for the control and ischaemia. In LAD occlusion, decreased entropy and increased complexity can be seen, i.e., the behaviour is more predictable with an increase in the degree of complexity of the system. RCA occlusion had the opposite effects, i.e., the phenomenon is less predictable and exhibits a lower degree of organisation. Finally, both entropy and complexity decrease during the reperfusion phase in LAD and RCA cases.<\/jats:p>","DOI":"10.3390\/e27010008","type":"journal-article","created":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T21:13:18Z","timestamp":1735247598000},"page":"8","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Spatio-Temporal Analysis of Acute Myocardial Ischaemia Based on Entropy\u2013Complexity Plane"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1572-4322","authenticated-orcid":false,"given":"Esteban R.","family":"Valverde","sequence":"first","affiliation":[{"name":"Grupo de Sistema Cardiovascular, Instituto de Ingenier\u00eda Biom\u00e9dica (IIBM), Facultad de Ingenier\u00eda, Universidad de Buenos Aires, Buenos Aires C1063, Argentina"},{"name":"Grupo de Neurociencia de Sistemas, Instituto de Fisiolog\u00eda y Biof\u00edsica \u201cBernardo Houssay\u201d (IFIBIO-Houssay), Departamento de Ciencias Fisiol\u00f3gicas, Facultad de Medicina, CONICET-Universidad de Buenos Aires, Buenos Aires C1121, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2337-2187","authenticated-orcid":false,"given":"Victoria","family":"Vampa","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias B\u00e1sicas, Facultad de Ingenier\u00eda, Universidad Nacional de La Plata, La Plata B1900, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1288-2528","authenticated-orcid":false,"given":"Osvaldo A.","family":"Rosso","sequence":"additional","affiliation":[{"name":"Instituto de F\u00edsica, Universidade Federal de Alagoas (UFAL), Macei\u00f3 57072-970, Brazil"},{"name":"Instituto de F\u00edsica La Plata (IFLP), CONICET-Universidad Nacional de La Plata, La Plata B1900, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5548-7528","authenticated-orcid":false,"given":"Pedro D.","family":"Arini","sequence":"additional","affiliation":[{"name":"Grupo de Sistema Cardiovascular, Instituto de Ingenier\u00eda Biom\u00e9dica (IIBM), Facultad de Ingenier\u00eda, Universidad de Buenos Aires, Buenos Aires C1063, Argentina"},{"name":"Grupo de Investigaci\u00f3n en Cardiose\u00f1ales, Instituto Argentino de Matem\u00e1tica \u201cAlberto P. Calder\u00f3n\u201d (IAM), CONICET, Buenos Aires C1425, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1109\/10.846692","article-title":"Wavelet time entropy, T wave morphology and myocardial ischaemia","volume":"47","author":"Lemire","year":"2000","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Farahabadi, E., Farahabadi, A., Rabbani, H., Dehnavi, A.M., and Mahjoob, M.P. (2010, January 24\u201328). An entropy-based method for ischaemia diagnosis using ECG signal in wavelet domain. 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Electrocardiol."}],"container-title":["Entropy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1099-4300\/27\/1\/8\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T17:00:36Z","timestamp":1760115636000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1099-4300\/27\/1\/8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,26]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1]]}},"alternative-id":["e27010008"],"URL":"https:\/\/doi.org\/10.3390\/e27010008","relation":{},"ISSN":["1099-4300"],"issn-type":[{"value":"1099-4300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,26]]}}}