{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T01:55:51Z","timestamp":1782698151429,"version":"3.54.5"},"reference-count":68,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Future Internet"],"abstract":"<jats:p>The blending of human and mechanical capabilities has become a reality in the realm of Industry 4.0. Enterprises are encouraged to design frameworks capable of harnessing the power of human and technological resources to enhance the era of Artificial Intelligence (AI). Over the past decade, AI technologies have transformed the competitive landscape, particularly during the pandemic. Consequently, the job market, at an international level, is transforming towards the integration of suitably skilled people in cutting edge technologies, emphasizing the need to focus on the upcoming super-smart society known as Society 5.0. The concept of a Humachine builds on the notion that humans and machines have a common future that capitalizes on the strengths of both humans and machines. Therefore, the aim of this paper is to identify the capabilities and distinguishing characteristics of both humans and machines, laying the groundwork for improving human\u2013machine interaction (HMI).<\/jats:p>","DOI":"10.3390\/fi15050162","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T01:33:40Z","timestamp":1682645620000},"page":"162","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":150,"title":["The Future of the Human\u2013Machine Interface (HMI) in Society 5.0"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7923-7363","authenticated-orcid":false,"given":"Dimitris","family":"Mourtzis","sequence":"first","affiliation":[{"name":"Laboratory for Manufacturing Systems and Automation, Department of Mechanical Engineering and Aeronautics, University of Patras, 26504 Rio Patras, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1191-4935","authenticated-orcid":false,"given":"John","family":"Angelopoulos","sequence":"additional","affiliation":[{"name":"Laboratory for Manufacturing Systems and Automation, Department of Mechanical Engineering and Aeronautics, University of Patras, 26504 Rio Patras, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3829-8247","authenticated-orcid":false,"given":"Nikos","family":"Panopoulos","sequence":"additional","affiliation":[{"name":"Laboratory for Manufacturing Systems and Automation, Department of Mechanical Engineering and Aeronautics, University of Patras, 26504 Rio Patras, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jmsy.2022.09.017","article-title":"Industry 5.0: Prospect and retrospect","volume":"65","author":"Leng","year":"2022","journal-title":"J. Manuf. Syst."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.jmsy.2022.07.010","article-title":"Industry 5.0 and Society 5.0\u2014Comparison, complementation and co-evolution","volume":"64","author":"Huang","year":"2022","journal-title":"J. Manuf. Syst."},{"key":"ref_3","unstructured":"Di Marino, C., Rega, A., Vitolo, F., and Patalano, S. (2022). Advances on Mechanics, Design Engineering and Manufacturing IV: Proceedings of the International Joint Conference on Mechanics, Design Engineering & Advanced Manufacturing, JCM 2022, Ischia, Italy, 1\u20133 June 2022, Springer International Publishing."},{"key":"ref_4","unstructured":"Mourtzis, D. (2021). Design and Operation of Production Networks for Mass Personalization in the Era of Cloud Technology, Elsevier."},{"key":"ref_5","unstructured":"Firyaguna, F., John, J., Khyam, M.O., Pesch, D., Armstrong, E., Claussen, H., and Poor, H.V. (2022). Towards industry 5.0: Intelligent reflecting surface (irs) in smart manufacturing. arXiv."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Sanders, N.R., and Wood, J.D. (2019). The Humachine: Humankind, Machines, and the Future of Enterprise, Routledge.","DOI":"10.4324\/9780429001178"},{"key":"ref_7","unstructured":"Mourtzis, D., Angelopoulos, J., and Panopoulos, N. (2019, January 18\u201321). From industry 4.0 to society 4.0: Identifying challenges and opportunities. Proceedings of the International Conference on Computers and Industrial Engineering, CIE, Beijing, China."},{"key":"ref_8","unstructured":"UNESCO (2023, March 31). Japan Pushing Ahead with Society 5.0 to Overcome Chronic Social Challenges. UNESCO Science Report: Towards 2030. Available online: https:\/\/www.unesco.org\/en\/articles\/japan-pushing-ahead-society-5."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Mourtzis, D., Angelopoulos, J., and Panopoulos, N. (2022). A Literature Review of the Challenges and Opportunities of the Transition from Industry 4.0 to Society 5.0. Energies, 15.","DOI":"10.3390\/en15176276"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1080\/00207543.2022.2118892","article-title":"The Industry 5.0 framework: Viability-based integration of the resilience, sustainability, and human-centricity perspectives","volume":"61","author":"Ivanov","year":"2022","journal-title":"Int. J. Prod. Res."},{"key":"ref_11","unstructured":"Saadati, Z., and Barenji, R.V. (2022). Industry 4.0: Technologies, Applications, and Challenges, Springer Nature."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1089\/omi.2017.0194","article-title":"Birth of industry 5.0: Making sense of big data with artificial intelligence, \u201cthe internet of things\u201d and next-generation technology policy","volume":"22","author":"Hekim","year":"2018","journal-title":"Omics J. Integr. Biol."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Aslam, F., Aimin, W., Li, M., and Ur Rehman, K. (2020). Innovation in the era of IoT and industry 5.0: Absolute innovation management (AIM) framework. Information, 11.","DOI":"10.3390\/info11020124"},{"key":"ref_14","first-page":"100257","article-title":"Industry 5.0: A survey on enabling technologies and potential applications","volume":"26","author":"Maddikunta","year":"2022","journal-title":"J. Ind. Inf. Integr."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.jmsy.2022.11.004","article-title":"Human centric platforms for personalized value creation in metaverse","volume":"65","author":"Mourtzis","year":"2022","journal-title":"J. Manuf. Syst."},{"key":"ref_16","unstructured":"Sar\u0131ipek, D.B., and Peluso, P. (2022). Society 5.0 A New Challenge to Humankind\u2019s Future, Okur Yazar Association."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Mourtzis, D., Angelopoulos, J., and Panopoulos, N. (2023). Blockchain Integration in the Era of Industrial Metaverse. Appl. Sci., 13.","DOI":"10.3390\/app13031353"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"S\u00e1, M.J., Santos, A.I., Serpa, S., and Miguel, F.C. (2021). Digitainability\u2014Digital competences post-COVID-19 for a sustainable society. Sustainability, 13.","DOI":"10.3390\/su13179564"},{"key":"ref_19","unstructured":"Ciobanu, A.C., and Me\u0219ni\u021b\u0103, G. (2022, January 24\u201325). AI Ethics for Industry 5.0\u2014From Principles to Practice. Proceedings of the Workshop of I-ESA, Valencia, Spain."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Rojas, C.N., Pe\u00f1afiel, G.A.A., Buitrago, D.F.L., and Romero, C.A.T. (2021). Society 5.0: A Japanese concept for a superintelligent society. Sustainability, 13.","DOI":"10.3390\/su13126567"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"47630","DOI":"10.1007\/s11356-023-25543-2","article-title":"The role of Society 5.0 in achieving sustainable development: A spherical fuzzy set approach","volume":"30","author":"Alimohammadlou","year":"2023","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_22","unstructured":"Martynov, V.V., Shavaleeva, D.N., and Zaytseva, A.A. (2019). 2019 International Conference \u201cQuality Management, Transport and Information Security, Information Technologies\u201d (IT&QM&IS), IEEE."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"107460","DOI":"10.1016\/j.ijpe.2019.07.033","article-title":"Science, technology and innovation ecosystem transformation toward society 5.0","volume":"220","author":"Fukuda","year":"2020","journal-title":"Int. J. Prod. Econ."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Mourtzis, D., Angelopoulos, J., and Panopoulos, N. (2022). A Teaching Factory Paradigm for Personalized Perception of Education based on Extended Reality (XR). SSRN Electron. J.","DOI":"10.2139\/ssrn.4071876"},{"key":"ref_25","unstructured":"(2023, March 31). Intelligent Machines\u2014Humachines, From the Editor in Chief John Benditt. MIT Technology Review, 1 May 1999. Available online: https:\/\/www.technologyreview.com\/1999\/05\/01\/275799\/humachines\/."},{"key":"ref_26","unstructured":"(2023, March 31). Oxford English Dictionary. \u201cMachine\u201d. Available online: https:\/\/www.oxfordlearnersdictionaries.com\/definition\/english\/machine_1."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1080\/00207543.2019.1636321","article-title":"Simulation in the design and operation of manufacturing systems: State of the art and new trends","volume":"58","author":"Mourtzis","year":"2020","journal-title":"Int. J. Prod. Res."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s11192-009-0146-3","article-title":"Software survey: VOSviewer, a computer program for bibliometric mapping","volume":"84","author":"Waltman","year":"2010","journal-title":"Scientometrics"},{"key":"ref_29","first-page":"1","article-title":"Human-computer interaction for development: The past, present, and future","volume":"5","author":"Ho","year":"2009","journal-title":"Inf. Technol. Int. Dev."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1109\/JPROC.2002.801449","article-title":"Integrating perceptual and cognitive modeling for adaptive and intelligent human-computer interaction","volume":"90","author":"Duric","year":"2002","journal-title":"Proc. IEEE"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1207\/S15327051HCI1701_1","article-title":"The scope and importance of human interruption in human-computer interaction design","volume":"17","author":"McFarlane","year":"2002","journal-title":"Hum. Comput. Interact."},{"key":"ref_32","unstructured":"Romero, D., Stahre, J., Wuest, T., Noran, O., Bernus, P., Fast-Berglund, \u00c5., and Gorecky, D. (2016, January 29\u201331). Towards an operator 4.0 typology: A human-centric perspective on the fourth industrial revolution technologies. Proceedings of the International Conference on Computers and Industrial Engineering (CIE46), Tianjin, China."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"43","DOI":"10.36897\/jme\/147160","article-title":"Operator 5.0: A survey on enabling technologies and a framework for digital manufacturing based on extended reality","volume":"22","author":"Mourtzis","year":"2022","journal-title":"J. Mach. Eng."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Jeon, M. (2017). Emotions and affect in human factors and human\u2013computer interaction: Taxonomy, theories, approaches, and methods. Emot. Affect. Hum. Factors Hum. Comput. Interact., 3\u201326.","DOI":"10.1016\/B978-0-12-801851-4.00001-X"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"012024","DOI":"10.1088\/1742-6596\/1577\/1\/012024","article-title":"Collaborative decision-making for human-technology interaction-a case study using an automated water bottling plant","volume":"1577","author":"Coetzer","year":"2020","journal-title":"J. Phys. Conf. Ser."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1108\/LHT-02-2020-0043","article-title":"Augmented intelligence technology. The ethical and practical problems of its implementation in libraries","volume":"39","year":"2021","journal-title":"Libr. Hi Tech"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1016\/j.procs.2022.01.385","article-title":"Artificial Intelligence or Augmented Intelligence? Impact on our lives, rights and ethics","volume":"200","author":"Petrillo","year":"2022","journal-title":"Procedia Comput. Sci."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"100677","DOI":"10.1109\/ACCESS.2021.3096662","article-title":"Human-Augmented Prescriptive Analytics with Interactive Multi-Objective Reinforcement Learning","volume":"9","author":"Lepenioti","year":"2021","journal-title":"IEEE Access"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"104646","DOI":"10.1016\/j.bspc.2023.104646","article-title":"Mixed reality-based brain computer interface system using an adaptive bandpass filter: Application to remote control of mobile manipulator","volume":"83","author":"Li","year":"2023","journal-title":"Biomed. Signal Process. Control."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1109\/86.847819","article-title":"Brain-computer interfaces based on the steady-state visual-evoked response","volume":"8","author":"Middendorf","year":"2000","journal-title":"IEEE Trans. Rehabil. Eng."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Kubacki, A. (2021). Use of Force Feedback Device in a Hybrid Brain-Computer Interface Based on SSVEP, EOG and Eye Tracking for Sorting Items. Sensors, 21.","DOI":"10.3390\/s21217244"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.cogr.2022.07.002","article-title":"A Survey of Quantum Computing Hybrid Applications with Brain-Computer Interface","volume":"2","author":"Huang","year":"2022","journal-title":"Cogn. Robot."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Liu, L., Wen, B., Wang, M., Wang, A., Zhang, J., Zhang, Y., Le, S., Zhang, L., and Kang, X. (2023, January 20\u201322). Implantable Brain-Computer Interface Based On Printing Technology. Proceedings of the 2023 11th International Winter Conference on Brain-Computer Interface (BCI), Gangwon, Republic of Korea.","DOI":"10.1109\/BCI57258.2023.10078643"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Mu, W., Fang, T., Wang, P., Wang, J., Wang, A., Niu, L., Bin, J., Liu, L., Zhang, J., and Jia, J. (2022, January 21\u201323). EEG Channel Selection Methods for Motor Imagery in Brain Computer Interface. Proceedings of the 2022 10th International Winter Conference on Brain-Computer Interface (BCI), Gangwon-do, Republic of Korea.","DOI":"10.1109\/BCI53720.2022.9734929"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Cho, J.H., Jeong, J.H., Kim, M.K., and Lee, S.W. (2021, January 22\u201324). Towards Neurohaptics: Brain-computer interfaces for decoding intuitive sense of touch. Proceedings of the 2021 9th International Winter Conference on Brain-Computer Interface (BCI), Gangwon, Republic of Korea.","DOI":"10.1109\/BCI51272.2021.9385331"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1109\/JSEN.2020.3017491","article-title":"Data analytics in steady-state visual evoked potential-based brain\u2013computer interface: A review","volume":"21","author":"Zhang","year":"2020","journal-title":"IEEE Sens. J."},{"key":"ref_47","unstructured":"Bussmann, S. (1998, January 15\u201317). An agent-oriented architecture for holonic manufacturing control. Proceedings of the First International Workshop on IMS, Lausanne, Switzerland."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.jmsy.2020.01.002","article-title":"A human-in-the-loop manufacturing control architecture for the next generation of production systems","volume":"54","author":"Cimini","year":"2020","journal-title":"J. Manuf. Syst."},{"key":"ref_49","unstructured":"Frank, M., Roehrig, P., and Pring, B. (2017). What to Do When Machines Do Everything: How to Get ahead in a World of AI, Algorithms, Bots, and Big Data, John Wiley & Sons. Available online: https:\/\/books.google.gr\/books."},{"key":"ref_50","first-page":"114","article-title":"Collaborative intelligence: Humans and AI are joining forces","volume":"96","author":"Wilson","year":"2018","journal-title":"Harv. Bus. Rev."},{"key":"ref_51","unstructured":"Gill, H. (2008, January 18\u201320). From vision to reality: Cyber-physical systems. Proceedings of the HCSS National Workshop on New Research Directions for High Confidence Transportation CPS: Automotive, Aviation, and Rail, Washington, DC, USA."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1016\/j.procir.2021.11.284","article-title":"A smart IoT platform for oncology patient diagnosis based on ai: Towards the human digital twin","volume":"104","author":"Mourtzis","year":"2021","journal-title":"Procedia CIRP"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s42454-022-00041-x","article-title":"A unified view of a human digital twin","volume":"4","author":"Miller","year":"2022","journal-title":"Hum. Intell. Syst. Integr."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2100228","DOI":"10.1002\/aisy.202100228","article-title":"Artificial intelligence-enabled sensing technologies in the 5G\/internet of things era: From virtual reality\/augmented reality to the digital twin","volume":"4","author":"Zhang","year":"2022","journal-title":"Adv. Intell. Syst."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Lin, Y., Chen, L., Ali, A., Nugent, C., Ian, C., Li, R., Gao, D., Wang, H., Wang, Y., and Ning, H. (2022). Human Digital Twin: A Survey. arXiv.","DOI":"10.21203\/rs.3.rs-2369073\/v1"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Casadei, R., Pianini, D., Viroli, M., and Weyns, D. (2022). Digital twins, virtual devices, and augmentations for self-organising cyber-physical collectives. Appl. Sci., 12.","DOI":"10.3390\/app12010349"},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Prendinger, H., Lester, J., and Ishizuka, M. (2022). Intelligent Virtual Agents. IVA 2008, Springer.","DOI":"10.1007\/978-3-540-85483-8"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"169","DOI":"10.31887\/DCNS.2020.22.2\/lvalmaggia","article-title":"Virtual reality as a clinical tool in mental health research and practice","volume":"22","author":"Bell","year":"2020","journal-title":"Dialogues Clin. Neurosci."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Boulos, M.N.K., and Zhang, P. (2021). Digital Twins: From Personalised Medicine to Precision Public Health. J. Pers. Med., 11.","DOI":"10.3390\/jpm11080745"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"26637","DOI":"10.1109\/ACCESS.2020.2971576","article-title":"Human digital twin for fitness management","volume":"8","author":"Barricelli","year":"2020","journal-title":"IEEE Access"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"758099","DOI":"10.3389\/frobt.2021.758099","article-title":"A modular digital twinning framework for safety assurance of collaborative robotics","volume":"8","author":"Douthwaite","year":"2021","journal-title":"Front. Robot. AI"},{"key":"ref_62","unstructured":"Ravid, B.Y., and Aharon-Gutman, M. (2022). The Social Digital Twin: The Social Turn in the Field of Smart Cities. Environ. Plan. B Urban Anal. City Sci."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1177\/08854122221137861","article-title":"Developing human-centered urban digital twins for community infrastructure resilience: A research agenda","volume":"38","author":"Ye","year":"2023","journal-title":"J. Plan. Lit."},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Singh, M., Fuenmayor, E., Hinchy, E.P., Qiao, Y., Murray, N., and Devine, D. (2021). Digital twin: Origin to future. Appl. Syst. Innov., 4.","DOI":"10.3390\/asi4020036"},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Ayd\u0131n, N., and Erdem, O.A. (2022, January 15\u201316). A Research on the New Generation Artificial Intelligence Technology Generative Pretraining Transformer 3. Proceedings of the 2022 3rd International Informatics and Software Engineering Conference (IISEC), Ankara, Turkey.","DOI":"10.1109\/IISEC56263.2022.9998298"},{"key":"ref_66","unstructured":"OpenAI (2023). GPT-4 Technical Report. arXiv."},{"key":"ref_67","unstructured":"Ayd\u0131n, \u00d6. (2022). Emerging Computer Technologies 2, \u0130zmir Akademi Dernegi."},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Lund, B.D., and Wang, T. (2023). Chatting about ChatGPT: How may AI and GPT impact academia and libraries?. Libr. Hi Tech News.","DOI":"10.1108\/LHTN-01-2023-0009"}],"container-title":["Future Internet"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1999-5903\/15\/5\/162\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:24:46Z","timestamp":1760124286000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1999-5903\/15\/5\/162"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,27]]},"references-count":68,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5]]}},"alternative-id":["fi15050162"],"URL":"https:\/\/doi.org\/10.3390\/fi15050162","relation":{},"ISSN":["1999-5903"],"issn-type":[{"value":"1999-5903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,27]]}}}