{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T03:36:53Z","timestamp":1782877013911,"version":"3.54.5"},"reference-count":11,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T00:00:00Z","timestamp":1410134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Informatics"],"abstract":"<jats:p>Decision support tools exist for oncologic follow up. Their main interest is to help physicians improve their oncologic readings but this theoretical benefit has to be quantified by concrete evidence. The purpose of the study was to evaluate and quantify the impact of using dedicated software on RECIST readings. A comparison was made between RECIST readings without dedicated application vs. readings using dedicated software (Myrian\u00ae XL-Onco, Intrasense, France) with specific functionalities such as 3D elastic target matching and automated calculation of tumoral response. A retrospective database of 40 patients who underwent a CT scan follow up was used (thoracic\/abdominal lesions). The reading panel was composed of two radiologists. Reading times, intra\/inter-operator reproducibility of measurements and RECIST response misclassifications were evaluated. On average, reading time was reduced by 49.7% using dedicated software. A more important saving was observed for lung lesions evaluations (63.4% vs. 36.1% for hepatic targets). Inter and intra-operator reproducibility of measurements was excellent for both reading methods. Using dedicated software prevented misclassifications on 10 readings out of 120  (eight due to calculation errors). The use of dedicated oncology software optimises RECIST evaluation by decreasing reading times significantly and avoiding response misclassifications due to manual calculation errors or approximations.<\/jats:p>","DOI":"10.3390\/informatics1020160","type":"journal-article","created":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T10:27:26Z","timestamp":1410172046000},"page":"160-173","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["How Using Dedicated Software Can Improve RECIST Readings"],"prefix":"10.3390","volume":"1","author":[{"given":"Amandine","family":"Ren\u00e9","sequence":"first","affiliation":[{"name":"University of Montpellier I & II\/Intrasense SA, Montpellier 34000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Aufort","sequence":"additional","affiliation":[{"name":"Medical Imaging Service, Clinique du Parc, Castelnau-Le-Lez 34170, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Medical Imaging Service, Clinique du Parc, Castelnau-Le-Lez 34170, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Daures","sequence":"additional","affiliation":[{"name":"University of Montpellier I, Epidemiology Biostatistics and Public Health, IURC,  Montpellier 34000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Chemouny","sequence":"additional","affiliation":[{"name":"Intrasense, SA, 1231 Avenue du Mondial 98, Montpellier 34000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Bonnel","sequence":"additional","affiliation":[{"name":"Intrasense, SA, 1231 Avenue du Mondial 98, Montpellier 34000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Gallix","sequence":"additional","affiliation":[{"name":"Department of Radiology, McGill University, Montr\u00e9al, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2014,9,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ejca.2008.10.026","article-title":"New response evaluation criteria in solid tumours: Revised RECIST guideline (Version 1.1)","volume":"45","author":"Eisenhauer","year":"2009","journal-title":"Eur. J. Cancer"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"509","DOI":"10.3109\/02841861003705794","article-title":"Interobserver and intraobserver variability in the response evaluation of cancer therapy according to RECIST and WHO-criteria","volume":"49","author":"Suzuki","year":"2010","journal-title":"Acta Oncol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3507","DOI":"10.1200\/JCO.1997.15.12.3507","article-title":"Response rate accuracy in oncology trials: Reasons for interobserver variability. Groupe Fran\u00e7ais d\u2019Immunoth\u00e9rapie of the F\u00e9d\u00e9ration Nationale des Centres de Lutte Contre le Cancer","volume":"15","author":"Thiesse","year":"1997","journal-title":"J. Clin. Oncol."},{"key":"ref_4","first-page":"399","article-title":"Tool support to enable evaluation of the clinical response to treatment","volume":"2008","author":"Levy","year":"2008","journal-title":"AMIA Ann. Symp. Proc."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3348\/kjr.2011.12.2.145","article-title":"A computer-aided diagnosis for evaluating lung nodules on chest CT: The current status and perspective","volume":"12","author":"Goo","year":"2011","journal-title":"Korean J. Radiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"618","DOI":"10.2214\/AJR.12.10136","article-title":"Consistency and Efficiency of CT Analysis of Metastatic Disease: Semi-automated Lesion Management Application Within a PACS","volume":"201","author":"Folio","year":"2013","journal-title":"Am. J. Roentgenol."},{"key":"ref_7","unstructured":"Williams, J.C. (1988, January 5\u20139). A data-based method for assessing and reducing human error to improve operational performance. Proceedings of the Conference Record for 1988 IEEE Fourth Conference on Human Factors and Power Plants, Monterey, CA, USA."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1136\/qshc.4.2.80","article-title":"Understanding adverse events: Human factors","volume":"4","author":"Reason","year":"1995","journal-title":"Qual. Health Care"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/jnci\/92.3.205","article-title":"New guidelines to evaluate the response to treatment in solid tumors","volume":"92","author":"Therasse","year":"2000","journal-title":"J. Natl. Cancer Inst."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Chaudet, H., and Anceaux, F. (2013). Informatique m\u00e9dicale, e-Sant\u00e9, Springer.","DOI":"10.1016\/S1773-035X(13)71877-X"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"851","DOI":"10.2214\/ajr.167.4.8819370","article-title":"Analysis of interobserver and intraobserver variability in CT tumor measurements","volume":"167","author":"Hopper","year":"1996","journal-title":"Am. J. Roentgenol."}],"container-title":["Informatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9709\/1\/2\/160\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:15:41Z","timestamp":1760217341000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9709\/1\/2\/160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,8]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,9]]}},"alternative-id":["informatics1020160"],"URL":"https:\/\/doi.org\/10.3390\/informatics1020160","relation":{},"ISSN":["2227-9709"],"issn-type":[{"value":"2227-9709","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,8]]}}}