{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:11:39Z","timestamp":1760058699596,"version":"build-2065373602"},"reference-count":18,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:00:00Z","timestamp":1745366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Informatics"],"abstract":"<jats:p>(1) Background: Mixed Reality (MR) technology, such as the HoloLens, offers a novel approach to preoperative education. This study evaluates its feasibility and effectiveness in improving patient comprehension and comfort during informed consent for pancreatoduodenectomy. (2) Methods: A single-center, randomized, controlled pilot study was conducted between February and May 2023. Patients recommended for pancreatoduodenectomy were randomized into a control group receiving standard education or an intervention group using the HoloLens. Pre- and post-intervention surveys assessed patient understanding and comfort. (3) Results: Nineteen patients participated (8 HoloLens, 11 control). Both groups showed improved comprehension post-intervention, but only the HoloLens group demonstrated a statistically significant increase (Z = \u22122.524, p = 0.012). MR users had a greater understanding of surgical steps compared to controls, and 75% of participants in both groups reported high comfort levels with the surgery. MR integration was feasible and did not disrupt clinical workflow. (4) Conclusions: These findings suggest that MR can enhance preoperative education for complex procedures. However, limitations include the small sample size and single-center design, necessitating larger studies to confirm its broader applicability. MR-based education represents a promising tool to improve patient engagement and comprehension in surgical decision making.<\/jats:p>","DOI":"10.3390\/informatics12020042","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T03:43:37Z","timestamp":1745379817000},"page":"42","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Enhanced Preoperative Pancreatoduodenectomy Patient Education Using Mixed Reality Technology: A Randomized Controlled Pilot Study"],"prefix":"10.3390","volume":"12","author":[{"given":"Jessica","family":"Heard","sequence":"first","affiliation":[{"name":"Department of Surgery, Methodist Richardson Medical Center, 2805, Richardson, TX 75082, USA"}]},{"given":"Paul","family":"Murdock","sequence":"additional","affiliation":[{"name":"Burnett School of Medicine, Texas Christian University, Fort Worth, TX 76104, USA"}]},{"given":"Juan","family":"Malo","sequence":"additional","affiliation":[{"name":"Department of Surgery, Methodist Richardson Medical Center, 2805, Richardson, TX 75082, USA"}]},{"given":"Joseph","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Surgery, Methodist Richardson Medical Center, 2805, Richardson, TX 75082, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1305-1520","authenticated-orcid":false,"given":"Sourodip","family":"Mukharjee","sequence":"additional","affiliation":[{"name":"Department of Surgery, Methodist Richardson Medical Center, 2805, Richardson, TX 75082, USA"}]},{"given":"Rohan","family":"Jeyarajah","sequence":"additional","affiliation":[{"name":"Department of Surgery, Methodist Richardson Medical Center, 2805, Richardson, TX 75082, USA"},{"name":"Burnett School of Medicine, Texas Christian University, Fort Worth, TX 76104, USA"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00423-019-01762-5","article-title":"Mortality and postoperative complications after different types of surgical reconstruction following pancreaticoduodenectomy\u2014A systematic review with meta-analysis","volume":"404","author":"Schorn","year":"2019","journal-title":"Langenbecks Arch. 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