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Our Smart, Transformative, EHR-based Approaches to Revolutionizing the Intensive Care Unit (STELAR ICU) consists of a framework of five best practices that make optimal use of objective data to guide clinicians caring for the sickest patients in our quaternary center. Our strategy has relied on an accessible data infrastructure, standardizing without protocolizing care, using technology to increase patient contact and time spent at the bedside, continuously re-evaluating performance in real-time, and acknowledging uncertainty by using electronic data to provide probabilistic weight to clinical decision-making. These strategies blur the lines between research and quality improvement, with the aim of achieving truly stellar patient outcomes.<\/jats:p>","DOI":"10.3390\/informatics5030037","type":"journal-article","created":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T11:47:41Z","timestamp":1536320861000},"page":"37","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The STELAR ICU: Leveraging Electronic Health Record Data to Foster Research and Optimize Patient Care"],"prefix":"10.3390","volume":"5","author":[{"given":"Christopher M.","family":"Horvat","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, University of Pittsburgh School of Medicine\/UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA"},{"name":"Division of Pediatric Health Informatics, University of Pittsburgh School of Medicine\/UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA 15224, USA"},{"name":"Department of Pediatrics, University of Pittsburgh School of Medicine\/UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA 15224, USA"}]},{"given":"Srinivasan","family":"Suresh","sequence":"additional","affiliation":[{"name":"Division of Pediatric Health Informatics, University of Pittsburgh School of Medicine\/UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA 15224, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0806-8005","authenticated-orcid":false,"given":"Robert S. B.","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, University of Pittsburgh School of Medicine\/UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA"},{"name":"Department of Pediatrics, University of Pittsburgh School of Medicine\/UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA 15224, USA"}]}],"member":"1968","published-online":{"date-parts":[[2018,9,7]]},"reference":[{"unstructured":"(2016, November 13). Introduction Meaningful Use CDC, Available online: http:\/\/www.cdc.gov\/ehrmeaningfuluse\/introduction.html.","key":"ref_1"},{"unstructured":"Olsen, L., Aisner, D., McGinnis, J.M., and Institute of Medicine (U.S.) (2007). The Learning Healthcare System: Workshop Summary, National Academies Press.","key":"ref_2"},{"unstructured":"(2018, August 30). Learning Health Systems, Available online: https:\/\/www.ahrq.gov\/professionals\/systems\/learning-health-systems\/index.html.","key":"ref_3"},{"doi-asserted-by":"crossref","unstructured":"Horvat, C.M., Ismail, H.M., Au, A.K., Garibaldi, L., Siripong, N., Kantawala, S., Aneja, R.K., Hupp, D.S., Kochanek, P.M., and Clark, R.S.B. (2018, September 06). Presenting Predictors and Temporal Trends of Treatment-Related Outcomes in Diabetic Ketoacidosis. Available online: https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/pedi.12663.","key":"ref_4","DOI":"10.1111\/pedi.12663"},{"doi-asserted-by":"crossref","unstructured":"Dhillon, N.K., Francis, S.E., Tatum, J.M., Keller, M., Barmparas, G., Gewertz, B.L., Gewertz, M.D., and Ley, E.J.M.D. (2018, July 31). Adverse Effects of Computers during Bedside Rounds in a Critical Care Unit. 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