{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:04:21Z","timestamp":1783461861188,"version":"3.55.0"},"reference-count":75,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Serbian Ministry of Science, Technological Development, and Innovations","award":["451-03-137\/2025-03\/ 200122"],"award-info":[{"award-number":["451-03-137\/2025-03\/ 200122"]}]},{"name":"Insights Lab at Penn State Great Valley","award":["451-03-137\/2025-03\/ 200122"],"award-info":[{"award-number":["451-03-137\/2025-03\/ 200122"]}]},{"name":"COMET centre ABC\u2014Austrian Blockchain Center by BMK, BMDW, and the provinces of Vienna, Lower Austria, and Vorarlberg","award":["451-03-137\/2025-03\/ 200122"],"award-info":[{"award-number":["451-03-137\/2025-03\/ 200122"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCP"],"abstract":"<jats:p>Artificial intelligence (AI) agents are increasingly shaping vital sectors of society, including healthcare, education, supply chains, and finance. As their influence grows, AI alignment research plays a pivotal role in ensuring these systems are trustworthy, transparent, and aligned with human values. Leveraging blockchain technology, proven over the past decade in enabling transparent, tamper-resistant distributed systems, offers significant potential to strengthen AI alignment. However, despite its potential, the current AI alignment literature has yet to systematically explore the effectiveness of blockchain in facilitating secure and ethical behavior in AI agents. While existing systematic literature reviews (SLRs) in AI alignment address various aspects of AI safety and AI alignment, this SLR specifically examines the gap at the intersection of AI alignment, blockchain, and ethics. To address this gap, this SLR explores how blockchain technology can overcome the limitations of existing AI alignment approaches. We searched for studies containing keywords from AI, blockchain, and ethics domains in the Scopus database, identifying 7110 initial records on 28 May 2024. We excluded studies which did not answer our research questions and did not discuss the thematic intersection between AI, blockchain, and ethics to a sufficient extent. The quality of the selected studies was assessed on the basis of their methodology, clarity, completeness, and transparency, resulting in a final number of 46 included studies, the majority of which were journal articles. Results were synthesized through quantitative topic analysis and qualitative analysis to identify key themes and patterns. The contributions of this paper include the following: (i) presentation of the results of an SLR conducted to identify, extract, evaluate, and synthesize studies on the symbiosis of AI alignment, blockchain, and ethics; (ii) summary and categorization of the existing benefits and challenges in incorporating blockchain for AI alignment within the context of ethics; (iii) development of a framework that will facilitate new research activities; and (iv) establishment of the state of evidence with in-depth assessment. The proposed blockchain-based AI alignment framework in this study demonstrates that integrating blockchain with AI alignment can substantially enhance robustness, promote public trust, and facilitate ethical compliance in AI systems.<\/jats:p>","DOI":"10.3390\/jcp5030050","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T10:25:34Z","timestamp":1753784734000},"page":"50","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Is Blockchain the Future of AI Alignment? Developing a Framework and a Research Agenda Based on a Systematic Literature Review"],"prefix":"10.3390","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7967-2843","authenticated-orcid":false,"given":"Alexander","family":"Neulinger","sequence":"first","affiliation":[{"name":"Research Institute for Cryptoeconomics, Vienna University of Economics and Business, Geb\u00e4ude AR, 6.OG, Perspektivstra\u00dfe 4, 1020 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4781-4470","authenticated-orcid":false,"given":"Lukas","family":"Sparer","sequence":"additional","affiliation":[{"name":"Research Institute for Cryptoeconomics, Vienna University of Economics and Business, Geb\u00e4ude AR, 6.OG, Perspektivstra\u00dfe 4, 1020 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4246-3479","authenticated-orcid":false,"given":"Maryam","family":"Roshanaei","sequence":"additional","affiliation":[{"name":"Information Technology, Cybersecurity Analytics and Operations, Penn State Abington, The Pennsylvania State University, University Park, PA 16802, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6704-353X","authenticated-orcid":false,"given":"Dragutin","family":"Ostoji\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Science, Department of Mathematics and Informatics, University of Kragujevac, 34000 Kraljevo, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7787-2441","authenticated-orcid":false,"given":"Jainil","family":"Kakka","sequence":"additional","affiliation":[{"name":"Engineering Department, Penn State Great Valley, The Pennsylvania State University, University Park, PA 16802, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7477-1973","authenticated-orcid":false,"given":"Du\u0161an","family":"Ramljak","sequence":"additional","affiliation":[{"name":"Engineering Department, Penn State Great Valley, The Pennsylvania State University, University Park, PA 16802, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.35882\/jeeemi.v4i1.1","article-title":"Artificial intelligence: A review of progress and prospects in medicine and healthcare","volume":"4","author":"Mishra","year":"2022","journal-title":"J. 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