{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T03:45:57Z","timestamp":1777347957842,"version":"3.51.4"},"reference-count":119,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Imaging"],"abstract":"<jats:p>Dual-energy CT (DECT) imaging has broadened the potential of CT imaging by offering multiple postprocessing datasets with a single acquisition at more than one energy level. DECT shows profound capabilities to improve diagnosis based on its superior material differentiation and its quantitative value. However, the potential of dual-energy imaging remains relatively untapped, possibly due to its intricate workflow and the intrinsic technical limitations of DECT. Knowing the clinical advantages of dual-energy imaging and recognizing its limitations and pitfalls is necessary for an appropriate clinical use. The aims of this paper are to review the physical and technical bases of DECT acquisition and analysis, to discuss the advantages and limitations of DECT in different clinical scenarios, to review the technical constraints in material labeling and quantification, and to evaluate the cutting-edge applications of DECT imaging, including artificial intelligence, qualitative and quantitative imaging biomarkers, and DECT-derived radiomics and radiogenomics.<\/jats:p>","DOI":"10.3390\/jimaging10070154","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T05:03:07Z","timestamp":1719378187000},"page":"154","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["What to Expect (and What Not) from Dual-Energy CT Imaging Now and in the Future?"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9494-9783","authenticated-orcid":false,"given":"Roberto","family":"Garc\u00eda-Figueiras","sequence":"first","affiliation":[{"name":"Department of Radiology, Hospital Cl\u00ednico Universitario de Santiago, Choupana, 15706 Santiago de Compostela, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9702-0451","authenticated-orcid":false,"given":"Laura","family":"Oleaga","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Clinic, C. de Villarroel, 170, 08036 Barcelona, Spain"}]},{"given":"Jordi","family":"Broncano","sequence":"additional","affiliation":[{"name":"HT M\u00e9dica, 14012 C\u00f3rdoba, Spain"}]},{"given":"Gonzalo","family":"Tard\u00e1guila","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Ribera Povisa, R\u00faa de Salamanca, 5, Vigo, 36211 Pontevedra, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2732-6161","authenticated-orcid":false,"given":"Gabriel","family":"Fern\u00e1ndez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Grupo Recoletas, 47007 Valladolid, Spain"}]},{"given":"Eliseo","family":"Va\u00f1\u00f3","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Universitario Nuestra Se\u00f1ora, del Rosario, C. del Pr\u00edncipe de Vergara, 53, 28006 Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1999-141X","authenticated-orcid":false,"given":"Elo\u00edsa","family":"Santos-Armentia","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Ribera Povisa, R\u00faa de Salamanca, 5, Vigo, 36211 Pontevedra, Spain"}]},{"given":"Ramiro","family":"M\u00e9ndez","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Universitario Nuestra Se\u00f1ora, del Rosario, C. del Pr\u00edncipe de Vergara, 53, 28006 Madrid, Spain"},{"name":"Department of Radiology, Hospital Universitario Cl\u00ednico San Carlos, Calle del Prof Mart\u00edn Lagos, 28040 Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9358-3396","authenticated-orcid":false,"given":"Antonio","family":"Luna","sequence":"additional","affiliation":[{"name":"HT M\u00e9dica, 14012 C\u00f3rdoba, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1369-2988","authenticated-orcid":false,"given":"Sandra","family":"Baleato-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Cl\u00ednico Universitario de Santiago, Choupana, 15706 Santiago de Compostela, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.rcl.2023.05.002","article-title":"Dual-Energy Computed Tomography: Technological Considerations","volume":"61","author":"Chung","year":"2023","journal-title":"Radiol. 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