{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:14:43Z","timestamp":1760242483119,"version":"build-2065373602"},"reference-count":21,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2017,9,27]],"date-time":"2017-09-27T00:00:00Z","timestamp":1506470400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Imaging"],"abstract":"<jats:p>In medical image processing, evaluating the variations of lesion volume plays a major role in many medical applications. It helps radiologists to follow-up with patients and examine the effects of therapy. Several approaches have been proposed to meet with medical expectations. The present work comes within this context. We present a new approach based on the local dissimilarity volume (LDV) that is a 3D representation of the local dissimilarity map (LDM). This map presents a useful means to compare two images, offering a localization of information. We proved the effectiveness of this method (LDV) compared to medical techniques used by radiologists. The result of simulations shows that we can quantify lesion volume by using the LDV method, which is an efficient way to calculate and localize the volume variation of anomalies. It allowed a time savings with the compete satisfaction of an expert during the medical treatment.<\/jats:p>","DOI":"10.3390\/jimaging3040041","type":"journal-article","created":{"date-parts":[[2017,9,27]],"date-time":"2017-09-27T10:52:25Z","timestamp":1506509545000},"page":"41","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Towards a Novel Approach for Tumor Volume Quantification"],"prefix":"10.3390","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7256-6367","authenticated-orcid":false,"given":"Amina","family":"Kharbach","sequence":"first","affiliation":[{"name":"LSE2I Laboratory, National School of Applied Sciences, Mohammed First University, 60000 Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benaissa","family":"Bellach","sequence":"additional","affiliation":[{"name":"LSE2I Laboratory, National School of Applied Sciences, Mohammed First University, 60000 Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Rahmoune","sequence":"additional","affiliation":[{"name":"LSE2I Laboratory, National School of Applied Sciences, Mohammed First University, 60000 Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Rahmoun","sequence":"additional","affiliation":[{"name":"LSE2I Laboratory, National School of Applied Sciences, Mohammed First University, 60000 Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanane","family":"Kacem","sequence":"additional","affiliation":[{"name":"LSE2I Laboratory, National School of Applied Sciences, Mohammed First University, 60000 Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2017,9,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Loening, A.M., and Gambhir, S.S. 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