{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:59:14Z","timestamp":1760237954807,"version":"build-2065373602"},"reference-count":40,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2020,7,4]],"date-time":"2020-07-04T00:00:00Z","timestamp":1593820800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005765","name":"Universidade de Lisboa","doi-asserted-by":"publisher","award":["PhD grant"],"award-info":[{"award-number":["PhD grant"]}],"id":[{"id":"10.13039\/501100005765","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia \u2013 Portugal","award":["SFRH\/BD\/135733\/2018","FCT-IBEB Strategic Project UIDB\/00645\/2020"],"award-info":[{"award-number":["SFRH\/BD\/135733\/2018","FCT-IBEB Strategic Project UIDB\/00645\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Imaging"],"abstract":"<jats:p>3D volume rendering may represent a complementary option in the visualization of Digital Breast Tomosynthesis (DBT) examinations by providing an understanding of the underlying data at once. Rendering parameters directly influence the quality of rendered images. The purpose of this work is to study the influence of two of these parameters (voxel dimension in z direction and sampling distance) on DBT rendered data. Both parameters were studied with a real phantom and one clinical DBT data set. The voxel size was changed from 0.085 \u00d7 0.085 \u00d7 1.0 mm3 to 0.085 \u00d7 0.085 \u00d7 0.085 mm3 using ten interpolation functions available in the Visualization Toolkit library (VTK) and several sampling distance values were evaluated. The results were investigated at 90\u00ba using volume rendering visualization with composite technique. For phantom quantitative analysis, degree of smoothness, contrast-to-noise ratio, and full width at half maximum of a Gaussian curve fitted to the profile of one disk were used. Additionally, the time required for each visualization was also recorded. Hamming interpolation function presented the best compromise in image quality. The sampling distance values that showed a better balance between time and image quality were 0.025 mm and 0.05 mm. With the appropriate rendering parameters, a significant improvement in rendered images was achieved.<\/jats:p>","DOI":"10.3390\/jimaging6070064","type":"journal-article","created":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T03:19:27Z","timestamp":1594005567000},"page":"64","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Optimization of Breast Tomosynthesis Visualization through 3D Volume Rendering"],"prefix":"10.3390","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1931-294X","authenticated-orcid":false,"given":"Ana M.","family":"Mota","sequence":"first","affiliation":[{"name":"Instituto de Biof\u00edsica e Engenharia Biom\u00e9dica, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"}]},{"given":"Matthew J.","family":"Clarkson","sequence":"additional","affiliation":[{"name":"Department of Medical Physics and Biomedical Engineering and the Centre for Medical Image Computing, University College London, London WC1E 6BT, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5247-4011","authenticated-orcid":false,"given":"Pedro","family":"Almeida","sequence":"additional","affiliation":[{"name":"Instituto de Biof\u00edsica e Engenharia Biom\u00e9dica, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8048-7896","authenticated-orcid":false,"given":"Nuno","family":"Matela","sequence":"additional","affiliation":[{"name":"Instituto de Biof\u00edsica e Engenharia Biom\u00e9dica, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2020,7,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ejca.2018.07.005","article-title":"Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018","volume":"103","author":"Ferlay","year":"2018","journal-title":"Eur. 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