{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T14:14:45Z","timestamp":1766067285815,"version":"build-2065373602"},"reference-count":76,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2021,2,11]],"date-time":"2021-02-11T00:00:00Z","timestamp":1613001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Imaging"],"abstract":"<jats:p>Multiparametric prostate magnetic resonance imaging (mpMRI) is widely used as a triage test for men at a risk of prostate cancer. However, the traditional role of mpMRI was confined to prostate cancer staging. Radiomics is the quantitative extraction and analysis of minable data from medical images; it is emerging as a promising tool to detect and categorize prostate lesions. In this paper we review the role of radiomics applied to prostate mpMRI in detection and localization of prostate cancer, prediction of Gleason score and PI-RADS classification, prediction of extracapsular extension and of biochemical recurrence. We also provide a future perspective of artificial intelligence (machine learning and deep learning) applied to the field of prostate cancer.<\/jats:p>","DOI":"10.3390\/jimaging7020034","type":"journal-article","created":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T16:12:10Z","timestamp":1613146330000},"page":"34","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Radiomics and Prostate MRI: Current Role and Future Applications"],"prefix":"10.3390","volume":"7","author":[{"given":"Giuseppe","family":"Cutaia","sequence":"first","affiliation":[{"name":"Section of Radiology, BiND, University Hospital \u201cPaolo Giaccone\u201d, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"La Tona","sequence":"additional","affiliation":[{"name":"Section of Radiology, BiND, University Hospital \u201cPaolo Giaccone\u201d, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9290-6103","authenticated-orcid":false,"given":"Albert","family":"Comelli","sequence":"additional","affiliation":[{"name":"Ri.Med Foundation, Via Bandiera 11, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0350-1794","authenticated-orcid":false,"given":"Federica","family":"Vernuccio","sequence":"additional","affiliation":[{"name":"Section of Radiology, BiND, University Hospital \u201cPaolo Giaccone\u201d, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Agnello","sequence":"additional","affiliation":[{"name":"Section of Radiology, BiND, University Hospital \u201cPaolo Giaccone\u201d, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4088-2020","authenticated-orcid":false,"given":"Cesare","family":"Gagliardo","sequence":"additional","affiliation":[{"name":"Section of Radiology, BiND, University Hospital \u201cPaolo Giaccone\u201d, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"Salvaggio","sequence":"additional","affiliation":[{"name":"Section of Radiology, BiND, University Hospital \u201cPaolo Giaccone\u201d, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natale","family":"Quartuccio","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Unit, ARNAS Ospedali Civico, Di Cristina e Benfratelli, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Letterio","family":"Sturiale","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Unit, ARNAS Ospedali Civico, Di Cristina e Benfratelli, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7189-1731","authenticated-orcid":false,"given":"Alessandro","family":"Stefano","sequence":"additional","affiliation":[{"name":"Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), 90015 Cefal\u00f9, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3420-0986","authenticated-orcid":false,"given":"Mauro","family":"Calamia","sequence":"additional","affiliation":[{"name":"Section of Radiology, BiND, University Hospital \u201cPaolo Giaccone\u201d, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaspare","family":"Arnone","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Unit, ARNAS Ospedali Civico, Di Cristina e Benfratelli, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Midiri","sequence":"additional","affiliation":[{"name":"Section of Radiology, BiND, University Hospital \u201cPaolo Giaccone\u201d, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2465-1185","authenticated-orcid":false,"given":"Giuseppe","family":"Salvaggio","sequence":"additional","affiliation":[{"name":"Section of Radiology, BiND, University Hospital \u201cPaolo Giaccone\u201d, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,11]]},"reference":[{"key":"ref_1","first-page":"130","article-title":"Radiomica e intelligenza artificiale: Nuove frontiere in medicina [Radiomics and artificial intelligence: New frontiers in medicine]","volume":"111","author":"Vernuccio","year":"2020","journal-title":"Recenti Prog. 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