{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T19:46:26Z","timestamp":1776973586426,"version":"3.51.4"},"reference-count":58,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T00:00:00Z","timestamp":1635292800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/M011089\/1"],"award-info":[{"award-number":["EP\/M011089\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/T028270\/1"],"award-info":[{"award-number":["EP\/T028270\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Imaging"],"abstract":"<jats:p>High spatio-angular resolution diffusion MRI (dMRI) has been shown to provide accurate identification of complex neuronal fiber configurations, albeit, at the cost of long acquisition times. We propose a method to recover intra-voxel fiber configurations at high spatio-angular resolution relying on a 3D kq-space under-sampling scheme to enable accelerated acquisitions. The inverse problem for the reconstruction of the fiber orientation distribution (FOD) is regularized by a structured sparsity prior promoting simultaneously voxel-wise sparsity and spatial smoothness of fiber orientation. Prior knowledge of the spatial distribution of white matter, gray matter, and cerebrospinal fluid is also leveraged. A minimization problem is formulated and solved via a stochastic forward\u2013backward algorithm. Simulations and real data analysis suggest that accurate FOD mapping can be achieved from severe kq-space under-sampling regimes potentially enabling high spatio-angular resolution dMRI in the clinical setting.<\/jats:p>","DOI":"10.3390\/jimaging7110226","type":"journal-article","created":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T22:00:23Z","timestamp":1635372023000},"page":"226","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fast Fiber Orientation Estimation in Diffusion MRI from kq-Space Sampling and Anatomical Priors"],"prefix":"10.3390","volume":"7","author":[{"given":"Marica","family":"Pesce","sequence":"first","affiliation":[{"name":"Institute of Sensors Signals and Systems (ISSS), Heriot-Watt University, Edinburgh EH14 4AS, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Audrey","family":"Repetti","sequence":"additional","affiliation":[{"name":"Institute of Sensors Signals and Systems (ISSS), Heriot-Watt University, Edinburgh EH14 4AS, UK"},{"name":"Department of Actuarial Mathematics & Statistics (AMS), Heriot-Watt University, Edinburgh EH14 4AS, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Aur\u00eda","sequence":"additional","affiliation":[{"name":"Signal Processing Lab (LTS5), \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, CH-1015 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Daducci","sequence":"additional","affiliation":[{"name":"Department of Computer Science, University of Verona, 37134 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Philippe","family":"Thiran","sequence":"additional","affiliation":[{"name":"Signal Processing Lab (LTS5), \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, CH-1015 Lausanne, Switzerland"},{"name":"Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne, CH-1011 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Wiaux","sequence":"additional","affiliation":[{"name":"Institute of Sensors Signals and Systems (ISSS), Heriot-Watt University, Edinburgh EH14 4AS, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,27]]},"reference":[{"key":"ref_1","unstructured":"Jara, H. 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