{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T15:12:28Z","timestamp":1787325148049,"version":"3.56.0"},"reference-count":130,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JSAN"],"abstract":"<jats:p>This paper investigates the integration of distributed computing and edge Artificial Intelligence (edge AI) as foundational enablers of sixth-generation (6G) mobile networks. Through a systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, encompassing over 200 peer-reviewed papers, architectural proposals, and standardization documents retrieved from IEEE Xplore, Scopus, Web of Science, MDPI, arXiv, ITU-R, 3GPP, and ETSI, this study provides a structured computational analysis of architectural approaches that integrate distributed computing paradigms and edge AI as core enablers of 6G. The analysis examines the evolution from cloud-centric to edge-centric computing, key edge AI techniques\u2014including Federated Learning (FL), Split Learning (SL), and edge-adapted Large AI Models (LAMs)\u2014and their role in enabling intelligent orchestration, resource optimization, and context-aware services. The comparative analysis demonstrates that edge computing architectures reduce end-to-end latency by 85\u201395% relative to cloud-centric deployments (under conditions of MEC servers within 1 km and 5G NR fronthaul), while federated learning with gradient compression achieves communication overhead reductions of up to 99% under IID data distributions and stable channel conditions. The results indicate that the tight integration of distributed computing and edge AI enhances network responsiveness, scalability, and adaptability, while also revealing persistent challenges related to orchestration complexity, resource constraints, security, and interoperability. The study concludes that holistic computational architectures and AI-native design principles are essential for the effective realization of 6G networks and for guiding future research and standardization efforts.<\/jats:p>","DOI":"10.3390\/jsan15030044","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T17:18:16Z","timestamp":1780679896000},"page":"44","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Computational Architectures for 6G Networks: Integrating Distributed Computing and Edge Artificial Intelligence"],"prefix":"10.3390","volume":"15","author":[{"given":"Evelio","family":"Astaiza Hoyos","sequence":"first","affiliation":[{"name":"Electronic Engineering Program, Faculty of Engineering, University of Quind\u00edo, Armenia 630004, Quind\u00edo, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8101-3764","authenticated-orcid":false,"given":"H\u00e9ctor Fabio","family":"Berm\u00fadez-Orozco","sequence":"additional","affiliation":[{"name":"Electronic Engineering Program, Faculty of Engineering, University of Quind\u00edo, Armenia 630004, Quind\u00edo, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9144-8016","authenticated-orcid":false,"given":"Nasly Cristina","family":"Rodr\u00edguez-Idrobo","sequence":"additional","affiliation":[{"name":"Occupational Health and Safety Program, Faculty of Health Sciences, University of Quind\u00edo, Armenia 630004, Quind\u00edo, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1109\/ACCESS.2024.3521579","article-title":"6G: The Intelligent Network of Everything\u2014A Comprehensive Vision, Survey, and Tutorial","volume":"13","author":"Pennanen","year":"2024","journal-title":"IEEE Access"},{"key":"ref_2","unstructured":"Chen, S., Liang, Y.-C., Sun, S., Kang, S., Cheng, W., and Peng, M. 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