{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:21:01Z","timestamp":1762917661708,"version":"build-2065373602"},"reference-count":50,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2016,3,10]],"date-time":"2016-03-10T00:00:00Z","timestamp":1457568000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Micromachines"],"abstract":"<jats:p>The use of a centrifugal microfluidic platform is an alternative to classical chromatographic procedures for radiochemistry. An ion-exchange support with respect to the in situ light-addressable process of elaboration is specifically designed to be incorporated as a radiochemical sample preparation module in centrifugal microsystem devices. This paper presents a systematic study of the synthesis of the polymeric porous monolith poly(ethylene glycol methacrylate-co-allyl methacrylate) used as a solid-phase support and the versatile and robust photografting process of the monolith based on thiol-ene click chemistry. The polymerization reaction is investigated, varying the formulation of the polymerisable mixture. The robustness of the stationary phase was tested in concentrated nitric acid. Thanks to their unique \u201ceasy-to-use\u201d features, centrifugal microfluidic platforms are potential successful candidates for the downscaling of chromatographic separation of radioactive samples (automation, multiplexing, easy integration in glove-boxes environment, and low cost of maintenance).<\/jats:p>","DOI":"10.3390\/mi7030045","type":"journal-article","created":{"date-parts":[[2016,3,10]],"date-time":"2016-03-10T10:53:48Z","timestamp":1457607228000},"page":"45","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Photochemical Synthesis and Versatile Functionalization Method of a Robust Porous Poly(ethylene glycol methacrylate-co-allyl methacrylate) Monolith Dedicated to Radiochemical Separation in a Centrifugal Microfluidic Platform"],"prefix":"10.3390","volume":"7","author":[{"given":"Marion","family":"Losno","sequence":"first","affiliation":[{"name":"Den\u2014Service d\u2019Etudes Analytiques et de R\u00e9activit\u00e9 des Surfaces (SEARS), CEA, Universit\u00e9 Paris-Saclay, F-91191 Gif sur Yvette, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Ferrante","sequence":"additional","affiliation":[{"name":"MMBM Group, Institut Curie Research Center, CNRS UMR 168, F-75005 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9","family":"Brennetot","sequence":"additional","affiliation":[{"name":"Den\u2014Service d\u2019Etudes Analytiques et de R\u00e9activit\u00e9 des Surfaces (SEARS), CEA, Universit\u00e9 Paris-Saclay, F-91191 Gif sur Yvette, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9r\u00f4me","family":"Varlet","sequence":"additional","affiliation":[{"name":"Den\u2014Service d\u2019Etudes Analytiques et de R\u00e9activit\u00e9 des Surfaces (SEARS), CEA, Universit\u00e9 Paris-Saclay, F-91191 Gif sur Yvette, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9cile","family":"Blanc","sequence":"additional","affiliation":[{"name":"Den\u2014Service d\u2019Etudes Analytiques et de R\u00e9activit\u00e9 des Surfaces (SEARS), CEA, Universit\u00e9 Paris-Saclay, F-91191 Gif sur Yvette, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Grenut","sequence":"additional","affiliation":[{"name":"Den\u2014Service d\u2019Etude du Comportement des Radionucl\u00e9ides (SECR), CEA, Universit\u00e9 Paris-Saclay, F-91191 Gif sur Yvette, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etienne","family":"Amblard","sequence":"additional","affiliation":[{"name":"Den\u2014Service d\u2019Etude du Comportement des Radionucl\u00e9ides (SECR), CEA, Universit\u00e9 Paris-Saclay, F-91191 Gif sur Yvette, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phanie","family":"Descroix","sequence":"additional","affiliation":[{"name":"MMBM Group, Institut Curie Research Center, CNRS UMR 168, F-75005 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clarisse","family":"Mariet","sequence":"additional","affiliation":[{"name":"Den\u2014Service d\u2019Etudes Analytiques et de R\u00e9activit\u00e9 des Surfaces (SEARS), CEA, Universit\u00e9 Paris-Saclay, F-91191 Gif sur Yvette, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2016,3,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/0003-2670(93)85194-O","article-title":"Separation and preconcentration of actinides from acidic media by extraction chromatography","volume":"281","author":"Horwitz","year":"1993","journal-title":"Anal. 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