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This study presents an exploratory evaluation of a virtual puppet system that enables real-time interaction by synchronously transmitting a human model\u2019s movements, facial gestures, and voice to a digital avatar. The system was personalized using each participant\u2019s restricted interests (RIs), identified through a clinical triangulation process involving therapist input, caregiver reports, and observation. After an initial technical validation with 16 neurotypical children, the system was evaluated in a proof-of-concept sample of 11 children with ASD (7 in an experimental group exposed to RI-based personalization and 4 in a control group interacting with a standard interface). Data sources included eye tracking and therapist-completed observational questionnaires. Across sessions, descriptive patterns in gaze fixation and therapist reports suggested that RI-based personalization may help sustain attention to the screen and support engagement with the therapeutic environment relative to non-personalized interaction. Heatmap patterns further indicated that children under the personalized condition visually explored RI-related elements within the scene. This study provides evidence of technical and procedural feasibility and generates hypotheses for future research.<\/jats:p>","DOI":"10.3390\/mti10060065","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:58:38Z","timestamp":1780473518000},"page":"65","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Personalizing Live Avatar Interaction for Children with ASD Through Restricted Interests: A Feasibility Study"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3327-2347","authenticated-orcid":false,"given":"Luis Fernando","family":"Guerrero-V\u00e1squez","sequence":"first","affiliation":[{"name":"Telecommunications and Telematics Research Group (GITEL), Universidad Polit\u00e9cnica Salesiana, Cuenca EC010103, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4802-607X","authenticated-orcid":false,"given":"Mart\u00edn","family":"L\u00f3pez-Nores","sequence":"additional","affiliation":[{"name":"atlanTTic Research Center for Telecommunication Technologies, University of Vigo, 36310 Vigo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1945-207X","authenticated-orcid":false,"given":"Henry J.","family":"Jara-Quito","sequence":"additional","affiliation":[{"name":"Telecommunications and Telematics Research Group (GITEL), Universidad Polit\u00e9cnica Salesiana, Cuenca EC010103, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7449-866X","authenticated-orcid":false,"given":"Dalila M.","family":"Gonz\u00e1lez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Telecommunications and Telematics Research Group (GITEL), Universidad Polit\u00e9cnica Salesiana, Cuenca EC010103, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9994-6063","authenticated-orcid":false,"given":"Jack Fernando","family":"Bravo-Torres","sequence":"additional","affiliation":[{"name":"Telecommunications and Telematics Research Group (GITEL), Universidad Polit\u00e9cnica Salesiana, Cuenca EC010103, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"7767","DOI":"10.3390\/ijerph110807767","article-title":"Technologies as Support Tools for Persons with Autistic Spectrum Disorder: A Systematic Review","volume":"11","year":"2014","journal-title":"Int. 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