{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T16:47:02Z","timestamp":1783183622424,"version":"3.54.6"},"reference-count":55,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T00:00:00Z","timestamp":1642032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Network"],"abstract":"<jats:p>Due to the rapid change of population structure, leading to lower birth rates and quick aging rates, the demand for blood supply is increasing significantly. In most countries, blood quality and origin are managed by blood management information systems, such as national authorities. Nevertheless, the traditional system has limitations in this field, such as a lack of detailed blood information, making it challenging to manage blood quality, supply, and demand. Hence, to solve these issues, this paper proposes a blockchain-based system called BloodChain, an improved system to support blood information management, providing more detailed information about blood, such as blood consumption and disposal. BloodChain exploits private blockchain techniques with a limited number of relatively fast and reliable participants, making them suitable for B2B (Business to Business) transactions. In this paper, we also develop a proposed system based on the architecture of Hyperledger Fabric. The evaluation of BloodChain is performed in several scenarios to prove our proposed model\u2019s effectiveness.<\/jats:p>","DOI":"10.3390\/network2010002","type":"journal-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T03:14:03Z","timestamp":1642130043000},"page":"21-35","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["BloodChain: A Blood Donation Network Managed by Blockchain Technologies"],"prefix":"10.3390","volume":"2","author":[{"given":"Hai Trieu","family":"Le","sequence":"first","affiliation":[{"name":"Department of Information Technology, Can Tho University of Technology, Can Tho City 900000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tran Thanh Lam","family":"Nguyen","sequence":"additional","affiliation":[{"name":"VNPT Information Technology Company, Ho Chi Minh City 700000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuan Anh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"School of Information and Communication Technology, Hanoi University of Science and Technology, Ha Noi 100000, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan Son","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Theoretical and Applied Sciences, University of Insubria, Via Ravasi 2, 21100 Varese, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7402-4166","authenticated-orcid":false,"given":"Nghia","family":"Duong-Trung","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Biotechnologie, Technische Universit\u00e4t Berlin, Stra\u00dfe des 17. Juni 135, 10623 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,13]]},"reference":[{"key":"ref_1","unstructured":"Nakamoto, S. (2021, November 25). Bitcoin: A Peer-to-Peer Electronic Cash System. Bitcoin.org. Disponible. Available online: https:\/\/bitcoin.org\/en\/bitcoin-paper."},{"key":"ref_2","first-page":"677","article-title":"Assuring Non-fraudulent Transactions in Cash on Delivery by Introducing Double Smart Contracts","volume":"10","author":"Le","year":"2019","journal-title":"Int. J. Adv. Comput. Sci. Appl."},{"key":"ref_3","first-page":"590","article-title":"Introducing multi shippers mechanism for decentralized cash on delivery system","volume":"10","author":"Le","year":"2019","journal-title":"Int. J. Adv. Comput. Sci. Appl."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Ha, X.S., Le, H.T., Metoui, N., and Duong-Trung, N. (2020, January 10\u201313). Dem-cod: Novel access-control-based cash on delivery mechanism for decentralized marketplace. Proceedings of the 2020 IEEE 19th International Conference on Trust, Security and Privacy in Computing and Communications (TrustCom), Guangzhou, China.","DOI":"10.1109\/TrustCom50675.2020.00023"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Ha, X.S., Le, T.H., Phan, T.T., Nguyen, H.H.D., Vo, H.K., and Duong-Trung, N. (2020, January 18\u201320). Scrutinizing trust and transparency in cash on delivery systems. Proceedings of the International Conference on Security, Privacy and Anonymity in Computation, Communication and Storage, Nanjing, China.","DOI":"10.1007\/978-3-030-68851-6_15"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Son, H.X., Le, T.H., Quynh, N.T.T., Huy, H.N.D., Duong-Trung, N., and Luong, H.H. (2020, January 28\u201329). Toward a Blockchain-Based Technology in Dealing with Emergencies in Patient-Centered Healthcare Systems. Proceedings of the International Conference on Mobile, Secure, and Programmable Networking, Paris, France.","DOI":"10.1007\/978-3-030-67550-9_4"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Duong-Trung, N., Son, H.X., Le, H.T., and Phan, T.T. (2020, January 10\u201312). On Components of a Patient-Centered Healthcare System Using Smart Contract. Proceedings of the 2020 4th International Conference on Cryptography, Security and Privacy, Nanjing China.","DOI":"10.1145\/3377644.3377668"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Duong-Trung, N., Son, H.X., Le, H.T., and Phan, T.T. (2020, January 10\u201312). Smart Care: Integrating Blockchain Technology into the Design of Patient-Centered Healthcare Systems. Proceedings of the 2020 4th International Conference on Cryptography, Security and Privacy, ICCSP 2020, Nanjing, China.","DOI":"10.1145\/3377644.3377667"},{"key":"ref_9","unstructured":"Thanh, L.N.T., Nguyen, T.A., Vo, H.K., Luong, H.H., Nguyen, H.T.K., Dao, A.T., and Ha, X.S. (2021, January 24\u201326). Toward a Unique IoT Network via Single Sign-On Protocol and Message Queue. Proceedings of the International Conference on Computer Information Systems and Industrial Management, E\u0142k, Poland."},{"key":"ref_10","first-page":"19","article-title":"UIP2SOP: A Unique IoT Network applying Single Sign-On and Message Queue Protocol","volume":"12","author":"Thanh","year":"2021","journal-title":"Int. J. Adv. Comput. Sci. Appl."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Thanh, L.N.T., Nguyen, T.A., Vo, H.K., Luong, H.H., Tuan, K.N.H., Dao, A.T., and Son, H.X. (2021, January 13\u201316). Toward a Security IoT Platform with High Rate Transmission and Low Energy Consumption. Proceedings of the International Conference on Computational Science and its Applications, Cagliari, Italy.","DOI":"10.1007\/978-3-030-86653-2_47"},{"key":"ref_12","unstructured":"Son, H.X., Nguyen, M.H., and Vo, H.K. (2019). Toward an privacy protection based on access control model in hybrid cloud for healthcare systems. Advances in Intelligent Systems and Computing, Proceedings of the International Joint Conference: 12th International Conference on Computational Intelligence in Security for Information Systems (CISIS 2019) and 10th International Conference on EUropean Transnational Education (ICEUTE 2019), Seville, Spain, 13\u201315 May 2019, Springer."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Thanh, L.N.T., Phien, N.N., Nguyen, T.A., Vo, H.K., Luong, H.H., Anh, T.D., Tuan, K.N.H., and Son, H.X. (2021). IoHT-MBA: An Internet of Healthcare Things (IoHT) Platform based on Microservice and Brokerless Architecture. Int. J. Adv. Comput. Sci. Appl., 12.","DOI":"10.14569\/IJACSA.2021.0120768"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"107661","DOI":"10.1016\/j.cie.2021.107661","article-title":"The healthcare supply chain network design with traceability: A novel algorithm","volume":"161","author":"Hajipour","year":"2021","journal-title":"Comput. Ind. Eng."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"115101","DOI":"10.1016\/j.eswa.2021.115101","article-title":"A blockchain-based system to enhance aircraft parts traceability and trackability for inventory management","volume":"179","author":"Ho","year":"2021","journal-title":"Expert Syst. Appl."},{"key":"ref_16","unstructured":"Emmanuel, J.C. (2017). The Blood Cold Chain, WHO Report."},{"key":"ref_17","first-page":"83","article-title":"The trends for nationwide blood collection and the supply of blood in Korea during 2002\u20132006","volume":"19","author":"Baek","year":"2008","journal-title":"Korean J. Blood Transfus."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13012-020-0965-4","article-title":"Overcoming barriers to evidence-based patient blood management: A restricted review","volume":"15","author":"Delaforce","year":"2020","journal-title":"Implement. Sci."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Ahram, T., Sargolzaei, A., Sargolzaei, S., Daniels, J., and Amaba, B. (2017, January 8\u201310). Blockchain technology innovations. Proceedings of the 2017 IEEE Technology & Engineering Management Conference (TEMSCON), Santa Clara, CA, USA.","DOI":"10.1109\/TEMSCON.2017.7998367"},{"key":"ref_20","unstructured":"Michael, J., Cohn, A., and Butcher, J.R. (2021, December 01). Blockchain Technology. Available online: https:\/\/www.steptoe.com\/images\/content\/1\/7\/v3\/171269\/LIT-FebMar18-Feature-Blockchain.pdf."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Shahriar Hazari, S., and Mahmoud, Q.H. (2020). Improving Transaction Speed and Scalability of Blockchain Systems via Parallel Proof of Work. Future Internet, 12.","DOI":"10.3390\/fi12080125"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Qu, Q., Xu, R., Chen, Y., Blasch, E., and Aved, A. (2021). Enable Fair Proof-of-Work (PoW) Consensus for Blockchains in IoT by Miner Twins (MinT). Future Internet, 13.","DOI":"10.20944\/preprints202111.0006.v1"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Feng, L., Zhang, H., Chen, Y., and Lou, L. (2018). Scalable dynamic multi-agent practical byzantine fault-tolerant consensus in permissioned blockchain. Appl. Sci., 8.","DOI":"10.3390\/app8101919"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Nijsse, J., and Litchfield, A. (2020). A Taxonomy of Blockchain Consensus Methods. Cryptography, 4.","DOI":"10.3390\/cryptography4040032"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Androulaki, E., Barger, A., Bortnikov, V., Cachin, C., Christidis, K., De Caro, A., Enyeart, D., Ferris, C., Laventman, G., and Manevich, Y. (2018, January 23\u201326). Hyperledger fabric: A distributed operating system for permissioned blockchains. Proceedings of the Thirteenth EuroSys Conference, Porto, Portugal.","DOI":"10.1145\/3190508.3190538"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"D\u00edaz-Santiso, J., and Fraga-Lamas, P. (2021). E-Voting System Using Hyperledger Fabric Blockchain and Smart Contracts. Eng. Proc., 7.","DOI":"10.3390\/engproc2021007011"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Kumar, T., Ramani, V., Ahmad, I., Braeken, A., Harjula, E., and Ylianttila, M. (2018, January 17\u201320). Blockchain utilization in healthcare: Key requirements and challenges. Proceedings of the 2018 IEEE 20th International Conference on e-Health Networking, Applications and Services (Healthcom), Ostrava, Czech Republic.","DOI":"10.1109\/HealthCom.2018.8531136"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"de Oliveira, M.T., Reis, L.H., Carrano, R.C., Seixas, F.L., Saade, D.C., Albuquerque, C.V., Fernandes, N.C., Olabarriaga, S.D., Medeiros, D.S., and Mattos, D.M. (2019, January 20\u201324). Towards a blockchain-based secure electronic medical record for healthcare applications. Proceedings of the ICC 2019-2019 IEEE International Conference on Communications (ICC), Shanghai, China.","DOI":"10.1109\/ICC.2019.8761307"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Wilber, K., Vayansky, S., Costello, N., Berdik, D., and Jararweh, Y. (2020, January 14\u201316). A Survey on Blockchain for Healthcare Informatics and Applications. Proceedings of the 2020 7th International Conference on Internet of Things: Systems, Management and Security (IOTSMS), Paris, France.","DOI":"10.1109\/IOTSMS52051.2020.9340232"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"45706","DOI":"10.1109\/ACCESS.2021.3065440","article-title":"Blockchain-based secure healthcare application for diabetic-cardio disease prediction in fog computing","volume":"9","author":"Shynu","year":"2021","journal-title":"IEEE Access"},{"key":"ref_31","unstructured":"Torky, M., and Hassanien, A.E. (2020). COVID-19 blockchain framework: Innovative approach. arXiv."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Kim, D. (2005, January 23\u201326). An integrated supply chain management system: A case study in healthcare sector. Proceedings of the International Conference on Electronic Commerce and Web Technologies, Copenhagen, Denmark.","DOI":"10.1007\/11545163_22"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"9233","DOI":"10.1166\/asl.2017.10061","article-title":"What is supply chain risk management? A review","volume":"23","author":"Shahbaz","year":"2017","journal-title":"Adv. Sci. Lett."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1080\/00207543.2013.878057","article-title":"Effect of firm characteristics, supplier relationships and techniques used on supply chain risk management (SCRM): An empirical investigation on French industrial firms","volume":"52","author":"Lavastre","year":"2014","journal-title":"Int. J. Prod. Res."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s10287-011-0133-z","article-title":"Supply chain network operations management of a blood banking system with cost and risk minimization","volume":"9","author":"Nagurney","year":"2012","journal-title":"Comput. Manag. Sci."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"605","DOI":"10.24874\/IJQR13.03-07","article-title":"A Model For Designing A Blood Supply Chain Network To Earthquake Disasters (Case Study: Tehran City)","volume":"13","author":"Armaghan","year":"2019","journal-title":"Int. J. Qual. Res."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.engappai.2018.03.004","article-title":"Designing and optimizing a sustainable supply chain network for a blood platelet bank under uncertainty","volume":"71","author":"Taleizadeh","year":"2018","journal-title":"Eng. Appl. Artif. Intell."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10479-009-0616-2","article-title":"Better management of blood supply-chain with GIS-based analytics","volume":"185","author":"Delen","year":"2011","journal-title":"Ann. Oper. Res."},{"key":"ref_39","first-page":"71","article-title":"Blockchain technology: Beyond bitcoin","volume":"2","author":"Crosby","year":"2016","journal-title":"Appl. Innov."},{"key":"ref_40","first-page":"3","article-title":"Blockchain in logistics and supply chain: Trick or treat?","volume":"Volume 23","author":"Hackius","year":"2017","journal-title":"Digitalization in Supply Chain Management and Logistics: Smart and Digital Solutions for an Industry 4.0 Environment, Proceedings of the Hamburg International Conference of Logistics (HICL), Hamburg, Germany, 12\u201313 October 2017"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Mettler, M. (2016, January 14\u201317). Blockchain technology in healthcare: The revolution starts here. Proceedings of the 2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom), Munich, Germany.","DOI":"10.1109\/HealthCom.2016.7749510"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Quynh, N.T.T., Son, H.X., Le, T.H., Huy, H.N.D., Vo, K.H., Luong, H.H., Tuan, K.N.H., Anh, T.D., and Duong-Trung, N. (2021, January 13\u201316). Toward a Design of Blood Donation Management by Blockchain Technologies. Proceedings of the International Conference on Computational Science and Its Applications, Cagliari, Italy.","DOI":"10.1007\/978-3-030-87010-2_6"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"H\u00f6lbl, M., Kompara, M., Kami\u0161ali\u0107, A., and Nemec Zlatolas, L. (2018). A systematic review of the use of blockchain in healthcare. Symmetry, 10.","DOI":"10.20944\/preprints201809.0136.v1"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Yaga, D., Mell, P., Roby, N., and Scarfone, K. (2019). Blockchain technology overview. arXiv.","DOI":"10.6028\/NIST.IR.8202"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"W\u00fcst, K., and Gervais, A. (2018, January 20\u201322). Do you need a blockchain?. Proceedings of the 2018 Crypto Valley Conference on Blockchain Technology (CVCBT), Zug, Switzerland.","DOI":"10.1109\/CVCBT.2018.00011"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Pradhan, N.R., Singh, A.P., and Kumar, V. (2021). Blockchain-enabled traceable, transparent transportation system for blood bank. Advances in VLSI, Communication, and Signal Processing, Springer.","DOI":"10.1007\/978-981-15-6840-4_25"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1109\/MSEC.2020.3012059","article-title":"Privacy Regulations, Smart Roads, Blockchain, and Liability Insurance: Putting Technologies to Work","volume":"19","author":"Campanile","year":"2020","journal-title":"IEEE Secur. Priv."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.telpol.2017.09.003","article-title":"Blockchain\u2019s roles in strengthening cybersecurity and protecting privacy","volume":"41","author":"Kshetri","year":"2017","journal-title":"Telecommun. Policy"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3934\/mfc.2018007","article-title":"A survey on security and privacy issues of blockchain technology","volume":"1","author":"Joshi","year":"2018","journal-title":"Math. Found. Comput."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Hoang, N.M., and Son, H.X. (2019, January 19\u201321). A dynamic solution for fine-grained policy conflict resolution. Proceedings of the 3rd International Conference on Cryptography, Security and Privacy, Kuala Lumpur, Malaysia.","DOI":"10.1145\/3309074.3309097"},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Son, H.X., and Hoang, N.M. (2019, January 19\u201321). A novel attribute-based access control system for fine-grained privacy protection. Proceedings of the 3rd International Conference on Cryptography, Security and Privacy, Kuala Lumpur, Malaysia.","DOI":"10.1145\/3309074.3309091"},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Son, H.X., Dang, T.K., and Massacci, F. (2017, January 12\u201315). REW-SMT: A new approach for rewriting xacml request with dynamic big data security policies. Proceedings of the International Conference on Security, Privacy and Anonymity in Computation, Communication and Storage, Guangzhou, China.","DOI":"10.1007\/978-3-319-72389-1_40"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Xuan, S.H., Tran, L.K., Dang, T.K., and Pham, Y.N. (2016, January 23\u201325). Rew-xac: An approach to rewriting request for elastic abac enforcement with dynamic policies. Proceedings of the 2016 International Conference on Advanced Computing and Applications (ACOMP), Tho City, Vietnam.","DOI":"10.1109\/ACOMP.2016.014"},{"key":"ref_54","first-page":"507","article-title":"Towards a fine-grained access control mechanism for privacy protection and policy conflict resolution","volume":"10","author":"Son","year":"2019","journal-title":"Int. J. Adv. Comput. Sci. Appl."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Thi, Q.N.T., Dang, T.K., Van, H.L., and Son, H.X. (2017, January 12\u201325). Using json to specify privacy preserving-enabled attribute-based access control policies. Proceedings of the International Conference on Security, Privacy and Anonymity in Computation, Communication and Storage, Guangzhou, China.","DOI":"10.1007\/978-3-319-72389-1_44"}],"container-title":["Network"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2673-8732\/2\/1\/2\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T14:28:55Z","timestamp":1760365735000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2673-8732\/2\/1\/2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,13]]},"references-count":55,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,3]]}},"alternative-id":["network2010002"],"URL":"https:\/\/doi.org\/10.3390\/network2010002","relation":{},"ISSN":["2673-8732"],"issn-type":[{"value":"2673-8732","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,13]]}}}