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The potential applications of the device were demonstrated by monitoring rheumatoid synovial fibroblasts (RSF) and HepG2 hepatocarcinoma cells in response to chemical and biological treatments. This technology could provide an alternative to conventional end-point assays used in the fields of chemotherapy, toxicology and drug discovery.<\/jats:p>","DOI":"10.3390\/s100403732","type":"journal-article","created":{"date-parts":[[2010,4,13]],"date-time":"2010-04-13T11:15:22Z","timestamp":1271157322000},"page":"3732-3740","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Multiwell Electrochemical Biosensor for Real-Time Monitoring of the Behavioural Changes of Cells in Vitro"],"prefix":"10.3390","volume":"10","author":[{"given":"Daman J.","family":"Adlam","sequence":"first","affiliation":[{"name":"University Dept Medicine, University of Manchester, MRI, Oxford Rd, Manchester, M13 9WL, UK"}]},{"given":"David E.","family":"Woolley","sequence":"additional","affiliation":[{"name":"University Dept Medicine, University of Manchester, MRI, Oxford Rd, Manchester, M13 9WL, UK"}]}],"member":"1968","published-online":{"date-parts":[[2010,4,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1002\/bit.10217","article-title":"Electrochemical monitoring of cell behaviour in vitro: a new technology","volume":"77","author":"Woolley","year":"2002","journal-title":"Biotechnol. 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